"Microglia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The third type of glial cell, along with astrocytes and oligodendrocytes (which together form the macroglia). Microglia vary in appearance depending on developmental stage, functional state, and anatomical location; subtype terms include ramified, perivascular, ameboid, resting, and activated. Microglia clearly are capable of phagocytosis and play an important role in a wide spectrum of neuropathologies. They have also been suggested to act in several other roles including in secretion (e.g., of cytokines and neural growth factors), in immunological processing (e.g., antigen presentation), and in central nervous system development and remodeling.
| Descriptor ID |
D017628
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| MeSH Number(s) |
A08.637.400 A11.650.400
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Microglia".
Below are MeSH descriptors whose meaning is more specific than "Microglia".
This graph shows the total number of publications written about "Microglia" by people in this website by year, and whether "Microglia" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 2 | 3 |
| 2014 | 3 | 1 | 4 |
| 2015 | 3 | 1 | 4 |
| 2016 | 2 | 2 | 4 |
| 2017 | 3 | 2 | 5 |
| 2018 | 3 | 1 | 4 |
| 2019 | 5 | 3 | 8 |
| 2020 | 6 | 5 | 11 |
| 2021 | 4 | 1 | 5 |
| 2022 | 2 | 4 | 6 |
| 2023 | 2 | 8 | 10 |
| 2024 | 3 | 4 | 7 |
| 2025 | 7 | 3 | 10 |
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Below are the most recent publications written about "Microglia" by people in Profiles.
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De novo pathogenic CSF1R variant implicates microglial dysfunction in pathogenesis of febrile infection-related epilepsy syndrome. Epilepsia. 2025 Sep; 66(9):e211-e218.
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TET2-mutant myeloid cells mitigate Alzheimer's disease progression via CNS infiltration and enhanced phagocytosis in mice. Cell Stem Cell. 2025 Aug 07; 32(8):1285-1298.e8.
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Retinal ganglion cell migration and viability requires the kinase LKB1. J Cell Biol. 2025 Jul 07; 224(7).
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A spatio-temporal brain miRNA expression atlas identifies sex-independent age-related microglial driven miR-155-5p increase. Nat Commun. 2025 May 17; 16(1):4588.
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Dampening of Microglial Activation With Nasal Foralumab Administration in Moderate Alzheimer's Disease Dementia. Clin Nucl Med. 2025 Aug 01; 50(8):756-757.
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Inhibition of soluble epoxide hydrolase confers neuroprotection and restores microglial homeostasis in a tauopathy mouse model. Mol Neurodegener. 2025 Apr 23; 20(1):44.
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Immune checkpoint TIM-3 regulates microglia and Alzheimer's disease. Nature. 2025 May; 641(8063):718-731.
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Nasal anti-CD3 monoclonal antibody ameliorates traumatic brain injury, enhances microglial phagocytosis and reduces neuroinflammation via IL-10-dependent Treg-microglia crosstalk. Nat Neurosci. 2025 Mar; 28(3):499-516.
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Benefits of equilibrium between microbiota- and host-derived ligands of the aryl hydrocarbon receptor after stroke in aged male mice. Nat Commun. 2025 Feb 19; 16(1):1767.
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Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy. Sci Transl Med. 2025 Jan 15; 17(781):eadk3690.