An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)

Descriptor ID	D009103
MeSH Number(s)	C10.114.375.500 C10.314.350.500 C20.111.258.250.500
Concept/Terms	Multiple Sclerosis Multiple Sclerosis Sclerosis, Multiple Sclerosis, Disseminated Disseminated Sclerosis MS (Multiple Sclerosis) Multiple Sclerosis, Acute Fulminating Multiple Sclerosis, Acute Fulminating

Below are MeSH descriptors whose meaning is more general than "Multiple Sclerosis".

Below are MeSH descriptors whose meaning is related to "Multiple Sclerosis".

Below are MeSH descriptors whose meaning is more specific than "Multiple Sclerosis".