SOX9 Transcription Factor
"SOX9 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A SOXE transcription factor that plays a critical role in regulating CHONDROGENESIS; OSTEOGENESIS; and male sex determination. Loss of function of the SOX9 transcription factor due to genetic mutations is a cause of CAMPOMELIC DYSPLASIA.
| Descriptor ID |
D055758
|
| MeSH Number(s) |
D12.776.260.719.500.500 D12.776.660.235.400.750.500.500 D12.776.664.235.400.750.500.500 D12.776.930.823.500.500
|
| Concept/Terms |
SOX9 Transcription Factor- SOX9 Transcription Factor
- Transcription Factor, SOX9
- SOX-9 Transcription Factor
- SOX 9 Transcription Factor
- Transcription Factor, SOX-9
|
Below are MeSH descriptors whose meaning is more general than "SOX9 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "SOX9 Transcription Factor".
This graph shows the total number of publications written about "SOX9 Transcription Factor" by people in this website by year, and whether "SOX9 Transcription Factor" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 6 | 6 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 3 | 4 |
| 2012 | 1 | 0 | 1 |
| 2013 | 3 | 2 | 5 |
| 2014 | 2 | 0 | 2 |
| 2015 | 2 | 1 | 3 |
| 2017 | 3 | 0 | 3 |
| 2018 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 3 | 3 |
| 2024 | 1 | 0 | 1 |
| 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "SOX9 Transcription Factor" by people in Profiles.
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Astrocytic Sox9 overexpression in Alzheimer's disease mouse models promotes A? plaque phagocytosis and preserves cognitive function. Nat Neurosci. 2026 Jan; 29(1):88-99.
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Role of Kctd13 in modulating AR and SOX9 expression in different penile cell populations. Andrology. 2025 Jul; 13(5):1201-1212.
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The IFITM5 mutation in osteogenesis imperfecta type V is associated with an ERK/SOX9-dependent osteoprogenitor differentiation defect. J Clin Invest. 2024 Jun 17; 134(15).
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SOX9 Governs Gastric Mucous Neck Cell Identity and Is Required for Injury-Induced Metaplasia. Cell Mol Gastroenterol Hepatol. 2023; 16(3):325-339.
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Inhibitory input directs astrocyte morphogenesis through glial GABABR. Nature. 2023 05; 617(7960):369-376.
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ASO silencing of a glycosyltransferase, Poglut1 , improves the liver phenotypes in mouse models of Alagille syndrome. Hepatology. 2023 11 01; 78(5):1337-1351.
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Sox9 directs divergent epigenomic states in brain tumor subtypes. Proc Natl Acad Sci U S A. 2022 07 19; 119(29):e2202015119.
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Temporospatial regulation of intraflagellar transport is required for the endochondral ossification in mice. Dev Biol. 2022 02; 482:91-100.
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Olfactory bulb astrocytes mediate sensory circuit processing through Sox9 in the mouse brain. Nat Commun. 2021 09 01; 12(1):5230.
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TFEB regulates murine liver cell fate during development and regeneration. Nat Commun. 2020 05 18; 11(1):2461.