Reduced Folate Carrier Protein
"Reduced Folate Carrier Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed folic acid transporter that functions via an antiporter mechanism which is coupled to the transport of organic phosphates.
Descriptor ID |
D058978
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MeSH Number(s) |
D12.776.157.530.450.074.500.299.750 D12.776.157.530.450.162.359 D12.776.157.530.937.622 D12.776.543.550.190.608 D12.776.543.585.450.074.500.224.750 D12.776.543.585.450.162.359 D12.776.543.585.937.743 D23.050.301.500.600.813 D23.050.705.552.600.663
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Concept/Terms |
Reduced Folate Carrier Protein- Reduced Folate Carrier Protein
- SLC19a1 Transporter
- Transporter, SLC19a1
- Folate Transporter 1
- Transporter 1, Folate
- SLC19a1 Protein
- Protein, SLC19a1
- Reduced Folate Carrier
- Carrier, Reduced Folate
- Folate Carrier, Reduced
- Solute Carrier Family 19, Member 1
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Below are MeSH descriptors whose meaning is more general than "Reduced Folate Carrier Protein".
Below are MeSH descriptors whose meaning is more specific than "Reduced Folate Carrier Protein".
This graph shows the total number of publications written about "Reduced Folate Carrier Protein" by people in this website by year, and whether "Reduced Folate Carrier Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
2005 | 0 | 5 | 5 |
2006 | 0 | 1 | 1 |
2008 | 0 | 2 | 2 |
2010 | 1 | 1 | 2 |
2013 | 1 | 0 | 1 |
2014 | 0 | 1 | 1 |
2017 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Reduced Folate Carrier Protein" by people in Profiles.
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Novel immunodeficiency caused by homozygous mutation in solute carrier family 19 member 1, which encodes the reduced folate carrier. Blood. 2023 06 29; 141(26):3226-3230.
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Upregulation of reduced folate carrier by vitamin D enhances brain folate uptake in mice lacking folate receptor alpha. Proc Natl Acad Sci U S A. 2019 08 27; 116(35):17531-17540.
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Regulation of Reduced Folate Carrier (RFC) by Vitamin D Receptor at the Blood-Brain Barrier. Mol Pharm. 2017 11 06; 14(11):3848-3858.
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LRP2 mediates folate uptake in the developing neural tube. J Cell Sci. 2014 May 15; 127(Pt 10):2261-8.
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Using a Bayesian hierarchical model for identifying single nucleotide polymorphisms associated with childhood acute lymphoblastic leukemia risk in case-parent triads. PLoS One. 2013; 8(12):e84658.
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Folate pathway and nonsyndromic cleft lip and palate. Birth Defects Res A Clin Mol Teratol. 2011 Jan; 91(1):50-60.
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Association of folate receptor (FOLR1, FOLR2, FOLR3) and reduced folate carrier (SLC19A1) genes with meningomyelocele. Birth Defects Res A Clin Mol Teratol. 2010 Aug; 88(8):689-94.
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Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer. J Nutr Biochem. 2009 Aug; 20(8):649-55.
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Embryonic development in the reduced folate carrier knockout mouse is modulated by maternal folate supplementation. Birth Defects Res A Clin Mol Teratol. 2008 Jul; 82(7):494-507.
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Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice. J Nutr Biochem. 2007 May; 18(5):305-12.