Sodium-Glucose Transporter 1
"Sodium-Glucose Transporter 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The founding member of the sodium glucose transport proteins. It is predominately expressed in the INTESTINAL MUCOSA of the SMALL INTESTINE.
| Descriptor ID |
D051269
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| MeSH Number(s) |
D12.776.157.530.450.625.437.500 D12.776.157.530.500.750.500 D12.776.157.530.937.696 D12.776.543.585.450.625.562.500 D12.776.543.585.500.750.500 D12.776.543.585.937.821
|
| Concept/Terms |
Sodium-Glucose Transporter 1- Sodium-Glucose Transporter 1
- Sodium Glucose Transporter 1
- SLC5A1 Protein
- Sodium-Glucose Cotransporter 1
- Sodium Glucose Cotransporter 1
- SGLT1 Protein
|
Below are MeSH descriptors whose meaning is more general than "Sodium-Glucose Transporter 1".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Glucose Transporter 1".
This graph shows the total number of publications written about "Sodium-Glucose Transporter 1" by people in this website by year, and whether "Sodium-Glucose Transporter 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sodium-Glucose Transporter 1" by people in Profiles.
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PKCd-mediated SGLT1 upregulation confers the acquired resistance of NSCLC to EGFR TKIs. Oncogene. 2021 Jul; 40(29):4796-4808.
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Intestinal stem cell-derived enteroids from morbidly obese patients preserve obesity-related phenotypes: Elevated glucose absorption and gluconeogenesis. Mol Metab. 2021 02; 44:101129.
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Editing Myosin VB Gene to Create Porcine Model of Microvillus Inclusion Disease, With Microvillus-Lined Inclusions and Alterations in Sodium Transporters. Gastroenterology. 2020 06; 158(8):2236-2249.e9.
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Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk. J Am Coll Cardiol. 2018 10 09; 72(15):1763-1773.
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Loss of MYO5B Leads to Reductions in Na+ Absorption With Maintenance of CFTR-Dependent Cl- Secretion in Enterocytes. Gastroenterology. 2018 12; 155(6):1883-1897.e10.
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Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism. Sci Rep. 2017 06 06; 7(1):2812.
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A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease. Sci Transl Med. 2016 06 01; 8(341):341ra76.
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Taste cell-expressed a-glucosidase enzymes contribute to gustatory responses to disaccharides. Proc Natl Acad Sci U S A. 2016 May 24; 113(21):6035-40.
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Development of sotagliflozin, a dual sodium-dependent glucose transporter 1/2 inhibitor. Diab Vasc Dis Res. 2015 Mar; 12(2):101-10.
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Greater dose-ranging effects on A1C levels than on glucosuria with LX4211, a dual inhibitor of SGLT1 and SGLT2, in patients with type 2 diabetes on metformin monotherapy. Diabetes Care. 2015 Mar; 38(3):431-8.