"Zinc Transporter 8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A zinc efflux transporter highly expressed by ISLET CELLS of the pancreas. It functions in the accumulation of zinc in intracellular vesicles and may be involved in INSULIN maturation and storage processes. Variations in the SLC30A8 gene are associated with susceptibility to DIABETES MELLITUS, TYPE 2.
| Descriptor ID |
D000075703
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| MeSH Number(s) |
D12.776.157.530.450.250.940 D12.776.157.530.937.952 D12.776.543.585.450.250.945 D12.776.543.585.937.975
|
| Concept/Terms |
Zinc Transporter 8- Zinc Transporter 8
- ZnT-8 Protein
- ZnT 8 Protein
- Slc30A8 Protein
- Solute Carrier Family 30 Member 8 Protein
|
Below are MeSH descriptors whose meaning is more general than "Zinc Transporter 8".
Below are MeSH descriptors whose meaning is more specific than "Zinc Transporter 8".
This graph shows the total number of publications written about "Zinc Transporter 8" by people in this website by year, and whether "Zinc Transporter 8" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Zinc Transporter 8" by people in Profiles.
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Can Non-HLA Single Nucleotide Polymorphisms Help Stratify Risk in TrialNet Relatives at Risk for Type 1 Diabetes? J Clin Endocrinol Metab. 2017 08 01; 102(8):2873-2880.
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Dissecting heterogeneity in paediatric Type 1 diabetes: association of TCF7L2 rs7903146 TT and low-risk human leukocyte antigen (HLA) genotypes. Diabet Med. 2017 02; 34(2):286-290.
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DPD epitope-specific glutamic acid decarboxylase (GAD)65 autoantibodies in children with Type 1 diabetes. Diabet Med. 2017 05; 34(5):641-646.
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Immunogenetics of type 1 diabetes mellitus. Mol Aspects Med. 2015 Apr; 42:42-60.
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SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity. J Neurosci. 2014 Oct 15; 34(42):14079-95.
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Islet autoantigens: structure, function, localization, and regulation. Cold Spring Harb Perspect Med. 2012 Aug 01; 2(8).
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No association between the type 2 diabetes mellitus susceptibility gene, SLC30A8 and schizophrenia in a Chinese population. Hum Psychopharmacol. 2012 Jul; 27(4):392-6.
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Prediction and prevention of Type 1 diabetes mellitus. J Diabetes. 2011 Mar; 3(1):48-57.
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Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians. Diabetes. 2008 Aug; 57(8):2226-33.