"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
|
| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
|
| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
|
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 6 | 5 | 11 |
| 1996 | 8 | 8 | 16 |
| 1997 | 3 | 9 | 12 |
| 1998 | 3 | 5 | 8 |
| 1999 | 7 | 6 | 13 |
| 2000 | 4 | 8 | 12 |
| 2001 | 7 | 5 | 12 |
| 2002 | 10 | 20 | 30 |
| 2003 | 7 | 12 | 19 |
| 2004 | 12 | 13 | 25 |
| 2005 | 14 | 17 | 31 |
| 2006 | 12 | 20 | 32 |
| 2007 | 10 | 15 | 25 |
| 2008 | 14 | 11 | 25 |
| 2009 | 10 | 17 | 27 |
| 2010 | 12 | 18 | 30 |
| 2011 | 13 | 16 | 29 |
| 2012 | 16 | 19 | 35 |
| 2013 | 7 | 17 | 24 |
| 2014 | 7 | 13 | 20 |
| 2015 | 11 | 13 | 24 |
| 2016 | 14 | 17 | 31 |
| 2017 | 12 | 24 | 36 |
| 2018 | 5 | 17 | 22 |
| 2019 | 8 | 18 | 26 |
| 2020 | 8 | 18 | 26 |
| 2021 | 8 | 15 | 23 |
| 2022 | 3 | 32 | 35 |
| 2023 | 4 | 18 | 22 |
| 2024 | 7 | 14 | 21 |
| 2025 | 4 | 3 | 7 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Menopause factors and alterations in gut microbiota and insulin homeostasis: A cross-sectional analysis of the microbiome and insulin longitudinal evaluation study (MILES). Diabetes Obes Metab. 2025 Oct; 27(10):5444-5454.
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The Disposition Index in Autoantibody-Positive Individuals at Risk for Type 1 Diabetes. Diabetes. 2025 Jul 01; 74(7):1196-1204.
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Metabolic clearance rate of insulin across the glucose tolerance spectrum by race and ethnicity in youth with obesity. Obesity (Silver Spring). 2025 Jul; 33(7):1365-1374.
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Effect of aerobic or resistance exercise, or both on insulin secretion, ciliary neurotrophic factor, and insulin-like growth factor-1 in dieting older adults with obesity. Clin Nutr. 2025 Aug; 51:50-62.
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Impact of Glucagon-like Peptide-1 Receptor Agonists on Metabolic Health in Liver Transplant Recipients. Transplantation. 2025 09 01; 109(9):e501-e507.
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International Society for Pediatric and Adolescent Diabetes Clinical Practice Consensus Guidelines 2024 Diabetes Technologies: Glucose Monitoring. Horm Res Paediatr. 2024; 97(6):615-635.
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A Glucose Fraction Independent of Insulin Secretion: Implications for Type 1 Diabetes Progression in Autoantibody-Positive Cohorts. Diabetes Technol Ther. 2025 Mar; 27(3):179-186.
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Insulin clearance at randomisation and in response to treatment in youth with type 2 diabetes: a secondary analysis of the TODAY randomised clinical trial. Diabetologia. 2025 Mar; 68(3):676-687.
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International Society for Pediatric and Adolescent Diabetes Clinical Practice Consensus Guidelines 2024: Diabetes Technologies - Insulin Delivery. Horm Res Paediatr. 2024; 97(6):636-662.
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Clinical Prediction Models Combining Routine Clinical Measures Have High Accuracy in Identifying Youth-Onset Type 2 Diabetes Defined by Maintained Endogenous Insulin Secretion: The SEARCH for Diabetes in Youth Study. Diabetes Care. 2024 Dec 01; 47(12):2110-2119.