"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
|
| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
|
| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
|
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 6 | 5 | 11 |
| 1996 | 8 | 7 | 15 |
| 1997 | 3 | 9 | 12 |
| 1998 | 3 | 4 | 7 |
| 1999 | 7 | 6 | 13 |
| 2000 | 4 | 7 | 11 |
| 2001 | 7 | 5 | 12 |
| 2002 | 10 | 20 | 30 |
| 2003 | 7 | 13 | 20 |
| 2004 | 12 | 14 | 26 |
| 2005 | 14 | 17 | 31 |
| 2006 | 12 | 19 | 31 |
| 2007 | 10 | 15 | 25 |
| 2008 | 14 | 10 | 24 |
| 2009 | 10 | 17 | 27 |
| 2010 | 12 | 18 | 30 |
| 2011 | 13 | 16 | 29 |
| 2012 | 16 | 17 | 33 |
| 2013 | 7 | 16 | 23 |
| 2014 | 6 | 13 | 19 |
| 2015 | 10 | 13 | 23 |
| 2016 | 13 | 17 | 30 |
| 2017 | 12 | 19 | 31 |
| 2018 | 5 | 16 | 21 |
| 2019 | 6 | 18 | 24 |
| 2020 | 8 | 16 | 24 |
| 2021 | 8 | 13 | 21 |
| 2022 | 3 | 28 | 31 |
| 2023 | 3 | 18 | 21 |
| 2024 | 6 | 11 | 17 |
| 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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International Society for Pediatric and Adolescent Diabetes Clinical Practice Consensus Guidelines 2024 Diabetes Technologies: Glucose Monitoring. Horm Res Paediatr. 2024; 97(6):615-635.
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A Glucose Fraction Independent of Insulin Secretion: Implications for Type 1 Diabetes Progression in Autoantibody-Positive Cohorts. Diabetes Technol Ther. 2025 Mar; 27(3):179-186.
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Insulin clearance at randomisation and in response to treatment in youth with type 2 diabetes: a secondary analysis of the TODAY randomised clinical trial. Diabetologia. 2025 Mar; 68(3):676-687.
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International Society for Pediatric and Adolescent Diabetes Clinical Practice Consensus Guidelines 2024: Diabetes Technologies - Insulin Delivery. Horm Res Paediatr. 2024; 97(6):636-662.
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Clinical Prediction Models Combining Routine Clinical Measures Have High Accuracy in Identifying Youth-Onset Type 2 Diabetes Defined by Maintained Endogenous Insulin Secretion: The SEARCH for Diabetes in Youth Study. Diabetes Care. 2024 Dec 01; 47(12):2110-2119.
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Noninsulin Diabetes Medications in Hospitalized Children and Adolescents. Crit Care Nurs Clin North Am. 2025 Mar; 37(1):19-33.
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Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome. Nat Commun. 2024 Oct 17; 15(1):8980.
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Random C-Peptide and Islet Antibodies at Onset Predict ? Cell Function Trajectory and Insulin Dependence in Pediatric Diabetes. Endocr Pract. 2024 Dec; 30(12):1149-1157.
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Psychosocial outcomes with the Omnipod? 5 Automated Insulin Delivery System in caregivers of very young children with type 1 diabetes. Diabetes Obes Metab. 2024 Dec; 26(12):5569-5579.
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On the pathogenesis of obesity: causal models and missing pieces of the puzzle. Nat Metab. 2024 Oct; 6(10):1856-1865.