THOMAS KOSTEN

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Psychiatry & Behavioral Sciences
Address2002 HOLCOMBE
vCardDownload vCard
    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Biochemistry and Molecular Pharmacology
    DivisionBiochemistry & Mol Pharmacology

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Neuroscience
    DivisionNeuroscience

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pathology & Immunology
    DivisionPathology


    Collapse Overview 
    Collapse overview
    Following a successful 25 year tenure as professor and chief of Psychiatry at Yale University and VA Connecticut, Dr. Kosten joined the Michael E. DeBakey Veterans Affairs Medical Center (MEDVAMC) in July 2006, bringing over 30 years of exemplary Federal service; the majority of which has been with the Department of Veterans Affairs. Over the period 2006-2011, Dr. Kosten served as the Research Director of the VA national Substance Use Disorders Quality Enhancement Research Initiative (QUERI) program, fully revitalizing a research-to-practice implementation program to provide proven, cutting-edge treatment to improve the lives of veteran populations across the VA health care system. With a joint appointment at Baylor College of Medicine (BCM), Dr. Kosten is the JH Waggoner Chair & Professor of Psychiatry, Pharmacology, Neuroscience and Immunology & Pathology. He is also vice-Chair for Psychiatry and Co-director of the Dan L. Duncan Institute for Clinical and Translational Research (ICTR) at Baylor College of Medicine. His other key appointment is Professor of Epidemiology and of Behavioral Sciences at MD Anderson Cancer Prevention Center. He established the Division of Addictions Psychiatry at Baylor and Yale and directs their NIH Medications Development Center for substance abuse. Since 2015 he has been co-PI of the Dept of Defense Consortium for Pharmacotherapy of Alcoholism and Substance Abuse (PASA) in collaboration with RTI in North Carolina.

    A recognized leader in clinical and translational sciences, Dr. Kosten is a recent past recipient of a Research Scientist Award (1987-2010) from the National Institute of Health (NIH), he has served on national and international review groups for medications and vaccines development in substance abuse, and is credited with the development of several cutting-edge discoveries in medications for addictions. A former Congressional Fellow in the House of Representatives, Dr. Kosten has been a visiting professor over the period 1987-2009 in several US as well as international academic institutions in Germany, Spain, Greece, China and Canada. He is the founding vice-chair for Added Qualifications in Addiction Psychiatry of the American Board of Psychiatry and Neurology. He is a distinguished fellow in the American Psychiatric Association and fellow of the American College of Neuropsychopharmacology, past president of the American Academy of Addiction Psychiatry, and past president of the College on Problems of Drug Dependence (CPDD). He has received several prestigious awards for clinical research and for his work in vaccine pharmacotherapy for drug addictions, particularly in treating cocaine, methamphetamine, and opiate addictions. He is the current Editor for the American Journal on Addictions, past Editor for the American Journal of Drug and Alcohol Abuse, and serves on the board of several notable journals in substance abuse. Additionally, Dr. Kosten retains ongoing recognition in the Best Doctors in America® ranking, an honor reserved by only 5% of the nation’s doctors. As of 2012, for the 12th year in a row, he has been named by U.S. News & World Report as a Top Doc®, ranking him among the top 10% of psychiatrists in the region, and for the 9th consecutive year, in the top 1% of psychiatrists in the field of Addictions Medicine. He is a much sought-after expert both nationally and internationally in the field of addictions with appearances on National Geographic, Discovery Channel, and PBS as well as print, radio, and online publications that include WIRED, NPR, and the Wall Street Journal, among others.

    Dr. Kosten’s recent work includes serving on the National Academy of Sciences, Institute of Medicine (IOM) committee on vaccines for substance abuse. He also served on the recently concluded IOM’s Committee on Prevention, Diagnosis, Treatment, and Management of Substance Use Disorders in the U.S. Armed Forces, a congressional mandate via the National Defense Authorization Act for Fiscal Year 2010 (Public Law 111-84), to conduct an independent study on substance use disorders in the military.

    From his studies in substance dependence, post-traumatic stress disorder, and neuroimaging he has published over 950 papers, books and reviews. His medication contributions include a cocaine and fentanyl vaccines, buprenorphine for opioid dependence, disulfiram for cocaine dependence, vasodilators for cocaine induced cerebral perfusion defects, and combining medications with contingency management for opioid and cocaine dependence.

    Collapse Research 
    Collapse research activities and funding
    R01DA035513     (KOSTEN, THOMAS RICHARD)May 1, 2015 - Mar 31, 2018
    NIH
    Complementary Combination Therapy for Cocaine Dependence
    Role: Principal Investigator

    DP1DA033502     (KOSTEN, THOMAS RICHARD)Sep 30, 2011 - Aug 31, 2017
    NIH
    Human methamphetamine vaccine: Translational Avante Garde Award
    Role: Principal Investigator

    U01DA023898     (ORSON, FRANK M)Aug 1, 2009 - Jul 31, 2012
    NIH
    Developing Immunotherapeutics for Methamphetamine Abuse
    Role: Co-Principal Investigator

    R01DA025223     (KOSTEN, THOMAS RICHARD)Sep 15, 2008 - Jan 31, 2015
    NIH
    Multisite Controlled Trial of Cocaine Vaccine (1of 6) Lead Site/ Houston Treatmen
    Role: Principal Investigator

    U01MH079639     (KOSTEN, THOMAS RICHARD)Mar 1, 2007 - Feb 28, 2011
    NIH
    Tropisetron with Risperidone for Schizophrenia
    Role: Principal Investigator

    R01DA018863     (KOSTEN, THOMAS RICHARD)Sep 28, 2004 - May 31, 2010
    NIH
    Heroin Addiction Treatment: Naltrexone and Lofexidine
    Role: Principal Investigator

    P50DA018197     (KOSTEN, THOMAS RICHARD)Sep 27, 2004 - May 31, 2015
    NIH
    Stimulant Pharmacotherapy: Noradrenergic Targets
    Role: Principal Investigator

    R01DA015477     (ROUNSAVILLE, BRUCE)Sep 27, 2002 - Jun 30, 2007
    NIH
    Cocaine Vaccine for Methadone Maintained Patients
    Role: Co-Principal Investigator

    R13DA013380     (KOSTEN, THOMAS RICHARD)Sep 30, 2000 - Aug 31, 2002
    NIH
    11TH - 15TH ANNUAL MEETINGS AND SYMPOSIA
    Role: Principal Investigator

    K05DA000454     (KOSTEN, THOMAS RICHARD)Apr 1, 2000 - Feb 28, 2011
    NIH
    Comorbidity in Cocaine and Opioid Pharmacotherapy
    Role: Principal Investigator

    P50DA012762     (KOSTEN, THOMAS RICHARD)Sep 30, 1999 - Feb 28, 2005
    NIH
    COCAINE PHARMACOTHERAPIES FOR COMORBID POPULATIONS
    Role: Principal Investigator

    R13DA012147     (KOSTEN, THOMAS RICHARD)Sep 5, 1998 - Aug 31, 2001
    NIH
    9TH/13TH ANNUAL MEETING AND SYMPOSIUM
    Role: Principal Investigator

    U19DA010946     (KOSTEN, THOMAS RICHARD)May 1, 1997 - Dec 31, 2005
    NIH
    THERAPEUTIC COCAINE VACCINE
    Role: Principal Investigator

    P50DA009250     (KOSTEN, THOMAS RICHARD)Sep 30, 1994 - Sep 30, 1999
    NIH
    YALE MEDICATIONS DEVELOPMENT RESEARCH CENTER
    Role: Principal Investigator

    R01DA008754     (AVANTS, SANDRA KELLY)Sep 30, 1993 - Dec 31, 2003
    NIH
    REDUCING HIV RISK IN METHADONE-MAINTAINED PATIENTS
    Role: Co-Principal Investigator

    S15DA008671     (KOSTEN, THOMAS RICHARD)Sep 15, 1993 - Aug 31, 1994
    NIH
    SMALL INSTRUMENTATION GRANT
    Role: Principal Investigator

    C06DA007837     (KOSTEN, THOMAS RICHARD)Sep 30, 1991 - Sep 29, 1994
    NIH
    THE YALE UNIVERSITY SUBSTANCE ABUSE RESEARCH CENTER
    Role: Principal Investigator

    R18DA006190     (KOSTEN, THOMAS RICHARD)Sep 30, 1989 - Aug 31, 1994
    NIH
    REDUCING AIDS RISKS
    Role: Principal Investigator

    R01DA005626     (ROUNSAVILLE, BRUCE)Aug 1, 1988 - May 31, 2007
    NIH
    Pharmacotherapy for opioid and cocaine dependence
    Role: Co-Principal Investigator

    R01DA004505     (KOSTEN, THOMAS RICHARD)Jul 1, 1987 - Jul 31, 1991
    NIH
    PHARMACOTHERAPY OF IV COCAINE USE IN METHADONE PATIENTS
    Role: Principal Investigator

    K02DA000112     (KOSTEN, THOMAS RICHARD)Mar 1, 1987 - Aug 31, 1997
    NIH
    AGONIST TO ANTAGONIST--NEW APPROACHES
    Role: Principal Investigator

    P50DA004060     (KOSTEN, THOMAS RICHARD)Aug 1, 1986 - Nov 30, 2000
    NIH
    CLINICAL RESEARCH CENTER FOR OPIOID AND COCAINE ABUSE
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zhou D, Li X, Wei S, Yu C, Wang D, Li Y, Li J, Liu J, Li S, Zhuang W, Li Y, Luo R, Liu Z, Liu J, Xu Y, Fan J, Zhu G, Xu W, Tang Y, Cho RY, Kosten TR, Zhang XY. Transcranial Direct Current Stimulation Combined With Repetitive Transcranial Magnetic Stimulation for Depression: A Randomized Clinical Trial. JAMA Netw Open. 2024 Nov 04; 7(11):e2444306. PMID: 39535797; PMCID: PMC11561687.
      Citations:    
    2. Bigdeli TB, Chatzinakos C, Bendl J, Barr PB, Venkatesh S, Gorman BR, Clarence T, Genovese G, Iyegbe CO, Peterson RE, Kolokotronis SO, Burstein D, Meyers JL, Li Y, Rajeevan N, Sayward F, Cheung KH, Project Among African-Americans to Explore Risks for Schizophrenia (PAARTNERS), Consortium on the Genomics of Schizophrenia (COGS), Genomic Psychiatry Cohort (GPC) Investigators, DeLisi LE, Kosten TR, Zhao H, Achtyes E, Buckley P, Malaspina D, Lehrer D, Rapaport MH, Braff DL, Pato MT, Fanous AH, Pato CN, PsychAD Consortium, Cooperative Studies Program (CSP) #572, Million Veteran Program (MVP), Huang GD, Muralidhar S, Michael Gaziano J, Pyarajan S, Girdhar K, Lee D, Hoffman GE, Aslan M, Fullard JF, Voloudakis G, Harvey PD, Roussos P. Biological Insights from Schizophrenia-associated Loci in Ancestral Populations. medRxiv. 2024 Aug 28. PMID: 39252912; PMCID: PMC11383513.
      Citations:    
    3. Petrakis IL, Nolen T, Vandergrift N, Hirsch S, Krystal JH, De Vivo M, Sabados J, Pisani E, Newcomb J, Kosten TR. Dexmedetomidine HCL (BXCL501) as a potential treatment for alcohol use disorder and comorbid PTSD: A phase 1b, placebo-controlled crossover laboratory study. Am J Addict. 2024 Aug 16. PMID: 39152094.
      Citations:    Fields:    
    4. Wilkinson AV, Chen B, Swann AC, Graham DP, Nielsen DA, Kosten TR, Loukas A, Mantey DS, Bataineh BS, Harrell MB. Use of cigarettes and e-cigarettes, impulsivity and anxiety: Influences on suicidal ideation among youth and young adults in Texas. Nicotine Tob Res. 2024 Jul 19. PMID: 39028574.
      Citations:    Fields:    
    5. Li X, Liu J, Wei S, Yu C, Wang D, Li Y, Li J, Zhuang W, Luo RC, Li Y, Liu Z, Su Y, Liu J, Xu Y, Fan J, Zhu G, Xu W, Tang Y, Yan H, Cho RY, Kosten TR, Zhou D, Zhang X. Cognitive enhancing effect of rTMS combined with tDCS in patients with major depressive disorder: a double-blind, randomized, sham-controlled study. BMC Med. 2024 Jun 20; 22(1):253. PMID: 38902735; PMCID: PMC11188255.
      Citations:    Fields:    Translation:Humans
    6. Fava M, Stahl SM, Pani L, De Martin S, Cutler AJ, Maletic V, Gorodetzky CW, Vocci FJ, Sapienza FL, Kosten TR, Kr?ger C, Champasa P, O'Gorman C, Guidetti C, Alimonti A, Comai S, Mattarei A, Folli F, Bushnell D, Traversa S, Inturrisi CE, Manfredi PL, Pappagallo M. Efficacy and Safety of Esmethadone (REL-1017) in Patients With Major Depressive Disorder and Inadequate Response to Standard Antidepressants: A Phase 3 Randomized Controlled Trial. J Clin Psychiatry. 2024 Jun 17; 85(3). PMID: 38917366.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    7. Miranda O, Kiehl SM, Qi X, Brannock MD, Kosten T, Ryan ND, Kirisci L, Wang Y, Wang L. Enhancing post-traumatic stress disorder patient assessment: leveraging natural language processing for research of domain criteria identification using electronic medical records. BMC Med Inform Decis Mak. 2024 Jun 04; 24(1):154. PMID: 38835009; PMCID: PMC11151516.
      Citations:    Fields:    Translation:Humans
    8. Pappagallo M, Kosten TR, Gorodetzky CW, Vocci FJ, Sapienza FL, De Martin S, Comai S, Mattarei A, Inturrisi CE, Manfredi PL. Letter to the Editor regarding 'Unique pharmacodynamic properties and low abuse liability of the ?-opioid receptor ligand (S)-methadone'. Mol Psychiatry. 2024 May 28. PMID: 38806691.
      Citations:    Fields:    
    9. Kosten TR. Vaccines as Immunotherapies for Substance Use Disorders. Am J Psychiatry. 2024 May 01; 181(5):362-371. PMID: 38706331.
      Citations: 2     Fields:    Translation:HumansAnimals
    10. Yao Y, Guo D, Lu TS, Liu FL, Huang SH, Diao MQ, Li SX, Zhang XJ, Kosten TR, Shi J, Bao YP, Lu L, Han Y. Efficacy and safety of psychedelics for the treatment of mental disorders: A systematic review and meta-analysis. Psychiatry Res. 2024 May; 335:115886. PMID: 38574699.
      Citations: 2     Fields:    Translation:HumansAnimals
    11. Cinciripini PM, Wetter DW, Wang J, Yu R, Kypriotakis G, Kumar T, Robinson JD, Cui Y, Green CE, Bergen AW, Kosten TR, Scherer SE, Shete S. Deep sequencing of candidate genes identified 14 variants associated with smoking abstinence in an ethnically diverse sample. Sci Rep. 2024 03 16; 14(1):6385. PMID: 38493193; PMCID: PMC10944542.
      Citations:    Fields:    Translation:Humans
    12. Bigdeli TB, Barr PB, Rajeevan N, Graham DP, Li Y, Meyers JL, Gorman BR, Peterson RE, Sayward F, Radhakrishnan K, Natarajan S, Nielsen DA, Wilkinson AV, Malhotra AK, Zhao H, Brophy M, Shi Y, O'Leary TJ, Gleason T, Przygodzki R, Pyarajan S, Muralidhar S, Gaziano JM, Huang GD, Concato J, Siever LJ, DeLisi LE, Kimbrel NA, Beckham JC, Swann AC, Kosten TR, Fanous AH, Cooperative Studies Program (CSP) #572, Aslan M, Harvey PD. Correlates of suicidal behaviors and genetic risk among United States veterans with schizophrenia or bipolar I disorder. Mol Psychiatry. 2024 Aug; 29(8):2399-2407. PMID: 38491344.
      Citations: 4     Fields:    Translation:Humans
    13. Kosten TR, Domingo CB. Highlights and insights from the 34th AAAP Annual Meeting and Scientific Symposium. Am J Addict. 2024 Mar; 33(2):115-116. PMID: 38536074.
      Citations:    Fields:    
    14. Miranda O, Kiehl S, Qi X, Ryan ND, Kirisci L, Brannock MD, Kosten T, Wang Y, Wang L. Enhancing post-traumatic stress disorder patient assessment: Leveraging Natural Language Processing for Research of Domain Criteria Identification using electronic medical records. Res Sq. 2024 Feb 21. PMID: 38464073; PMCID: PMC10925404.
      Citations:    
    15. Barr PB, Bigdeli TB, Meyers JL, Peterson RE, Sanchez-Roige S, Mallard TT, Dick DM, Harden KP, Wilkinson A, Graham DP, Nielsen DA, Swann AC, Lipsky RK, Kosten TR, Aslan M, Harvey PD, Kimbrel NA, Beckham JC, Million Veteran Program (MVP)Cooperative Studies Program (CSP) #572. Correlates of Risk for Disinhibited Behaviors in the Million Veteran Program Cohort. JAMA Psychiatry. 2024 Feb 01; 81(2):188-197. PMID: 37938835; PMCID: PMC10633411.
      Citations:    Fields:    Translation:Humans
    16. Miranda O, Fan P, Qi X, Wang H, Brannock MD, Kosten TR, Ryan ND, Kirisci L, Wang L. DeepBiomarker2: Prediction of Alcohol and Substance Use Disorder Risk in Post-Traumatic Stress Disorder Patients Using Electronic Medical Records and Multiple Social Determinants of Health. J Pers Med. 2024 Jan 14; 14(1). PMID: 38248795; PMCID: PMC10817272.
      Citations: 2     
    17. Miranda O, Fan P, Qi X, Wang H, Brannock MD, Kosten T, Ryan ND, Kirisci L, Wang L. Prediction of adverse events risk in patients with comorbid post-traumatic stress disorder and alcohol use disorder using electronic medical records by deep learning models. Drug Alcohol Depend. 2024 Feb 01; 255:111066. PMID: 38217979; PMCID: PMC10853953.
      Citations:    Fields:    Translation:Humans
    18. Wang D, Tian Y, Chen J, Zhu R, Li J, Zhou H, Chen D, Wang L, Kosten TR, Zhang XY, Kosten TR. Ginkgo biloba for Tardive Dyskinesia and Plasma MnSOD Activity: Association with MnSOD Ala-9Val Variant: A Randomized, Double-blind Trial. Curr Neuropharmacol. 2024; 22(14):2443-2452. PMID: 38919004; PMCID: PMC11451319.
      Citations:    Fields:    Translation:HumansAnimalsCTClinical Trials
    19. Wang DM, Chen DC, Xiu MH, Wang L, Kosten TR, Zhang XY. A double-blind, randomized controlled study of the effects of celecoxib on clinical symptoms and cognitive impairment in patients with drug-na?ve first episode schizophrenia: pharmacogenetic impact of cyclooxygenase-2 functional polymorphisms. Neuropsychopharmacology. 2024 Apr; 49(5):893-902. PMID: 37903861; PMCID: PMC10948781.
      Citations:    Fields:    Translation:Humans
    20. Miranda O, Fan P, Qi X, Wang H, Brannock MD, Kosten T, Ryan ND, Kirisci L, Wang L. Prediction of Adverse Events Risk in Patients with Comorbid Post- Traumatic Stress Disorder and Alcohol Use Disorder Using Electronic Medical Records by Deep Learning Models. Res Sq. 2023 Sep 18. PMID: 37790550; PMCID: PMC10543461.
      Citations:    
    21. Davis LL, Petrakis IL, Pilkinton PD, Nolen T, Vandergrift N, Hirsch S, Norrholm SD, Kosten TR. Comorbid alcohol use disorder and posttraumatic stress disorder: A proof-of-concept randomized placebo-controlled trial of buprenorphine and naltrexone combination treatment. Alcohol Clin Exp Res (Hoboken). 2023 Sep; 47(9):1756-1772. PMID: 37468230.
      Citations:    
    22. Su S, Zhao Y, Zeng N, Liu X, Zheng Y, Sun J, Zhong Y, Wu S, Ni S, Gong Y, Zhang Z, Gao N, Yuan K, Yan W, Shi L, Ravindran AV, Kosten T, Shi J, Bao Y, Lu L. Epidemiology, clinical presentation, pathophysiology, and management of long COVID: an update. Mol Psychiatry. 2023 Oct; 28(10):4056-4069. PMID: 37491461.
      Citations: 5     Fields:    Translation:HumansCells
    23. Barr PB, Bigdeli TB, Meyers JL, Peterson RE, Sanchez-Roige S, Mallard TT, Dick DM, Paige Harden K, Wilkinson A, Graham DP, Nielsen DA, Swann A, Lipsky RK, Kosten T, Aslan M, Harvey PD, Kimbrel NA, Beckham JC. Correlates of Risk for Disinhibited Behaviors in the Million Veteran Program Cohort. medRxiv. 2023 Jul 11. PMID: 37034805; PMCID: PMC10081391.
      Citations:    
    24. Yang M, Liu L, Cui H, Deng C, Xiong W, Zhao G, Du S, Kosten TR, Chen H, Li Z, Zhang X. Dynamic functional thalamocortical dysconnectivity in schizophrenia correlates to antipsychotics response. Schizophrenia (Heidelb). 2023 Jul 04; 9(1):40. PMID: 37402747; PMCID: PMC10319786.
      Citations:    
    25. Yammine L, Verrico CD, Versace F, Webber HE, Suchting R, Weaver MF, Kosten TR, Alibhai H, Cinciripini PM, Lane SD, Schmitz JM. Exenatide as an adjunct to nicotine patch for smoking cessation and prevention of postcessation weight gain among treatment-seeking smokers with pre-diabetes and/or overweight: study protocol for a randomised, placebo-controlled clinical trial. BMJ Open. 2023 06 14; 13(6):e072707. PMID: 37316311; PMCID: PMC10277057.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    26. Shram MJ, Henningfield JE, Apseloff G, Gorodetzky CW, De Martin S, Vocci FL, Sapienza FL, Kosten TR, Huston J, Buchhalter A, Ashworth J, Lanier R, Folli F, Mattarei A, Guidetti C, Comai S, O'Gorman C, Traversa S, Inturrisi CE, Manfredi PL, Pappagallo M. The novel uncompetitive NMDA receptor antagonist esmethadone (REL-1017) has no meaningful abuse potential in recreational drug users. Transl Psychiatry. 2023 06 07; 13(1):192. PMID: 37286536; PMCID: PMC10247777.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    27. Aloi MS, Poblete GF, Oldham J, Patriquin MA, Nielsen DA, Kosten TR, Salas R. miR-124-3p target genes identify globus pallidus role in suicide ideation recovery in borderline personality disorder. Npj Ment Health Res. 2023; 2(1):8. PMID: 37712050; PMCID: PMC10500603.
      Citations:    
    28. Miranda O, Fan P, Qi X, Wang H, Brannock MD, Kosten T, Ryan ND, Kirisci L, Wang L. DeepBiomarker2: Prediction of alcohol and substance use disorder risk in post-traumatic stress disorder patients using electronic medical records and multiple social determinants of health. Res Sq. 2023 May 25. PMID: 37292589; PMCID: PMC10246255.
      Citations:    
    29. Million Veteran Program (MVP), Cooperative Studies Program (CSP) #572, Bigdeli TB, Barr PB, Rajeevan N, Graham DP, Li Y, Meyers JL, Gorman BR, Peterson RE, Sayward F, Radhakrishnan K, Natarajan S, Nielsen DA, Wilkinson AV, Malhotra AK, Zhao H, Brophy M, Shi Y, O'Leary TJ, Gleason T, Przygodzki R, Pyarajan S, Muralidhar S, Gaziano JM, Huang GD, Concato J, Siever LJ, DeLisi LE, Kimbrel NA, Beckham JC, Swann AC, Kosten TR, Fanous AH, Aslan M, Harvey PD. Correlates of suicidal behaviors and genetic risk among United States veterans with schizophrenia or bipolar I disorder. medRxiv. 2023 Mar 08. PMID: 36945597; PMCID: PMC10029042.
      Citations:    
    30. Grimm SL, Mendez EF, Stertz L, Meyer TD, Fries GR, Gandhi T, Kanchi R, Selvaraj S, Teixeira AL, Kosten TR, Gunaratne P, Coarfa C, Walss-Bass C. MicroRNA-mRNA networks are dysregulated in opioid use disorder postmortem brain: Further evidence for opioid-induced neurovascular alterations. Front Psychiatry. 2022; 13:1025346. PMID: 36713930; PMCID: PMC9878702.
      Citations: 2     
    31. Kiluk BD, Kleykamp BA, Comer SD, Griffiths RR, Huhn AS, Johnson MW, Kampman KM, Pravetoni M, Preston KL, Vandrey R, Bergeria CL, Bogenschutz MP, Brown RT, Dunn KE, Dworkin RH, Finan PH, Hendricks PS, Houtsmuller EJ, Kosten TR, Lee DC, Levin FR, McRae-Clark A, Raison CL, Rasmussen K, Turk DC, Weiss RD, Strain EC. Clinical Trial Design Challenges and Opportunities for Emerging Treatments for Opioid Use Disorder: A Review. JAMA Psychiatry. 2023 01 01; 80(1):84-92. PMID: 36449315; PMCID: PMC10297827.
      Citations:    Fields:    Translation:Humans
    32. Lang X, Wang D, Zhou H, Wang L, Kosten TR, Zhang XY. P50 inhibition defects, psychopathology and gray matter volume in patients with first-episode drug-naive schizophrenia. Asian J Psychiatr. 2023 Feb; 80:103421. PMID: 36563611.
      Citations:    Fields:    Translation:Humans
    33. Cruz B, Vozella V, Carper BA, Xu JC, Kirson D, Hirsch S, Nolen T, Bradley L, Fain K, Crawford M, Kosten TR, Zorrilla EP, Roberto M. FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder. Neuropsychopharmacology. 2023 07; 48(8):1144-1154. PMID: 36396784; PMCID: PMC10267127.
      Citations: 4     Fields:    Translation:Animals
    34. Kosten TR, Haile CN, Domingo CB, Norton EB. Anti-Cocaine IgA Rather Than IgG Mediates Vaccine Protection from Cocaine Use. Pharmaceutics. 2022 Nov 03; 14(11). PMID: 36365186; PMCID: PMC9697488.
      Citations:    
    35. Gong Y, Liu X, Su S, Bao Y, Kosten TR, Lu L. Addressing mental health issues amid the COVID-19 pandemic: a wake-up call. Sci Bull (Beijing). 2022 Nov 30; 67(22):2259-2262. PMID: 36311542; PMCID: PMC9598251.
      Citations: 4     Fields:    
    36. Haile CN, Baker MD, Sanchez SA, Lopez Arteaga CA, Duddupudi AL, Cuny GD, Norton EB, Kosten TR, Kosten TA. An Immunconjugate Vaccine Alters Distribution and Reduces the Antinociceptive, Behavioral and Physiological Effects of Fentanyl in Male and Female Rats. Pharmaceutics. 2022 Oct 26; 14(11). PMID: 36365109; PMCID: PMC9694531.
      Citations: 4     
    37. Wang DM, Zhu RR, Tian Y, Uludag K, Chen JJ, Zhou HX, Wang L, Kosten TR, Zhang XY. Association between MnSOD Activity and Cognitive Impairment in Unmedicated First-Episode Schizophrenia: Regulated by MnSOD Ala-9Val Gene Polymorphism. Antioxidants (Basel). 2022 Oct 04; 11(10). PMID: 36290704; PMCID: PMC9598731.
      Citations: 1     
    38. Yue JL, Yuan K, Bao YP, Meng SQ, Shi L, Fang Q, Guo XJ, Cao L, Sun YK, Lu TS, Zeng N, Yan W, Han Y, Sun J, Shi J, Kosten TR, Xue YX, Wu P, Lu L. The effect of a methadone-initiated memory reconsolidation updating procedure in opioid use disorder: A translational study. EBioMedicine. 2022 Nov; 85:104283. PMID: 36182773; PMCID: PMC9525804.
      Citations:    Fields:    Translation:HumansAnimals
    39. Kosten TR, Domingo CB, Haile CN, Nielsen DA. A Clinical Trial of Entolimod a TLR-5 Adjuvant for Vaccines Using Diphtheria or Tetanus as Carrier Proteins. Vaccines (Basel). 2022 Sep 22; 10(10). PMID: 36298456; PMCID: PMC9611255.
      Citations:    
    40. Bigdeli TB, Voloudakis G, Barr PB, Gorman BR, Genovese G, Peterson RE, Burstein DE, Velicu VI, Li Y, Gupta R, Mattheisen M, Tomasi S, Rajeevan N, Sayward F, Radhakrishnan K, Natarajan S, Malhotra AK, Shi Y, Zhao H, Kosten TR, Concato J, O'Leary TJ, Przygodzki R, Gleason T, Pyarajan S, Brophy M, Huang GD, Muralidhar S, Gaziano JM, Aslan M, Fanous AH, Harvey PD, Roussos P, Cooperative Studies Program (CSP) #572 and Million Veteran Program (MVP). Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia, Bipolar Disorder, and Depression Among Adults in the US Veterans Affairs Health Care System. JAMA Psychiatry. 2022 Sep 14. PMID: 36103194; PMCID: PMC9475441.
      Citations:    
    41. Haile CN, Varner KJ, Huijing X, Arora R, Orson FM, Kosten TR, Kosten TA. Active and Passive Immunization with an Anti-Methamphetamine Vaccine Attenuates the Behavioral and Cardiovascular Effects of Methamphetamine. Vaccines (Basel). 2022 Sep 09; 10(9). PMID: 36146588; PMCID: PMC9503672.
      Citations:    
    42. Kosten TR, Domingo C. 2021 Year in review: Adjusting to a post-COVID "Normal". Am J Addict. 2022 07; 31(4):268-269. PMID: 35843899; PMCID: PMC9349397.
      Citations:    Fields:    Translation:Humans
    43. Yuan K, Zheng YB, Wang YJ, Sun YK, Gong YM, Huang YT, Chen X, Liu XX, Zhong Y, Su SZ, Gao N, Lu YL, Wang Z, Liu WJ, Que JY, Yang YB, Zhang AY, Jing MN, Yuan CW, Zeng N, Vitiello MV, Patel V, Fazel S, Minas H, Thornicroft G, Fan TT, Lin X, Yan W, Shi L, Shi J, Kosten T, Bao YP, Lu L. A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action. Mol Psychiatry. 2022 08; 27(8):3214-3222. PMID: 35668158; PMCID: PMC9168354.
      Citations:    Fields:    
    44. Zeng N, Zhao YM, Yan W, Li C, Lu QD, Liu L, Ni SY, Mei H, Yuan K, Shi L, Li P, Fan TT, Yuan JL, Vitiello MV, Kosten T, Kondratiuk AL, Sun HQ, Tang XD, Liu MY, Lalvani A, Shi J, Bao YP, Lu L. A systematic review and meta-analysis of long term physical and mental sequelae of COVID-19 pandemic: call for research priority and action. Mol Psychiatry. 2023 01; 28(1):423-433. PMID: 35668159; PMCID: PMC9168643.
      Citations: 1     Fields:    
    45. Swann AC, Graham DP, Wilkinson AV, Kosten TR. Suicide Risk in a National VA Sample: Roles of Psychiatric Diagnosis, Behavior Regulation, Substance Use, and Smoking. J Clin Psychiatry. 2022 06 06; 83(3). PMID: 35687859.
      Citations:    Fields:    Translation:Humans
    46. Zhu C, Guan X, Wang Y, Liu J, Kosten TR, Xiu M, Wu F, Zhang X. Low-Dose Ziprasidone in Combination with Sertraline for First-Episode Drug-Na?ve Patients with Schizophrenia: a Randomized Controlled Trial. Neurotherapeutics. 2022 04; 19(3):1037-1046. PMID: 35467271; PMCID: PMC9294111.
      Citations:    Fields:    Translation:Humans
    47. Poblete G, Nguyen T, Gosnell S, Sofela O, Patriquin M, Mathew SJ, Swann A, Nielsen DA, Kosten TR, Salas R. A Novel Approach to Link Genetics and Human MRI Identifies AKAP7-Dependent Subicular/Prefrontal Functional Connectivity as Altered in Suicidality. Chronic Stress (Thousand Oaks). 2022 Jan-Dec; 6:24705470221083700. PMID: 35340866; PMCID: PMC8941704.
      Citations:    
    48. Nielsen DA, Walker R, Graham DP, Nielsen EM, Hamon SC, Hillhouse M, Shmueli-Blumberg D, Lawson WB, Shores-Wilson K, Settles-Reaves BD, Rotrosen J, Trivedi MH, Saxon AJ, Ling W, Kosten TR. Moderation of buprenorphine therapy for cocaine dependence efficacy by variation of the Prodynorphin gene. Eur J Clin Pharmacol. 2022 Jun; 78(6):965-973. PMID: 35218405.
      Citations:    Fields:    Translation:Humans
    49. Petrakis I, Springer SA, Davis C, Ralevski E, Gu L, Lew R, Hermos J, Nuite M, Gordon AJ, Kosten TR, Nunes EV, Rosenheck R, Saxon AJ, Swift R, Goldberg A, Ringer R, Ferguson R. Rationale, design and methods of VA-BRAVE: a randomized comparative effectiveness trial of two formulations of buprenorphine for treatment of opioid use disorder in veterans. Addict Sci Clin Pract. 2022 01 31; 17(1):6. PMID: 35101115; PMCID: PMC8802273.
      Citations:    Fields:    Translation:HumansCells
    50. Morice CK, Yammine L, Yoon J, Lane SD, Schmitz JM, Kosten TR, De La Garza R, Verrico CD. Comorbid alcohol use and post-traumatic stress disorders: Pharmacotherapy with aldehyde dehydrogenase 2 inhibitors versus current agents. Prog Neuropsychopharmacol Biol Psychiatry. 2022 04 20; 115:110506. PMID: 34995723.
      Citations:    Fields:    Translation:Humans
    51. Truong TT, Kosten TR. Current status of vaccines for substance use disorders: A brief review of human studies. J Neurol Sci. 2022 Mar 15; 434:120098. PMID: 34952345.
      Citations: 2     Fields:    Translation:HumansAnimals
    52. Zheng YB, Sun J, Liu L, Zhao YM, Yan W, Yuan K, Su SZ, Lu ZA, Huang YT, Liu L, Zeng N, Zhu XM, Gong YM, Lin X, Meng SQ, Wong SYS, Ran MS, Shi J, Shi L, Kosten T, Bao YP, Lu L. COVID-19 Vaccine-Related Psychological Stress Among General Public in China. Front Psychiatry. 2021; 12:774504. PMID: 34950070; PMCID: PMC8689133.
      Citations: 5     
    53. Han Y, Yuan K, Wang Z, Liu WJ, Lu ZA, Liu L, Shi L, Yan W, Yuan JL, Li JL, Shi J, Liu ZC, Wang GH, Kosten T, Bao YP, Lu L. Neuropsychiatric manifestations of COVID-19, potential neurotropic mechanisms, and therapeutic interventions. Transl Psychiatry. 2021 09 30; 11(1):499. PMID: 34593760; PMCID: PMC8482959.
      Citations: 8     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    54. Liu L, Ni SY, Yan W, Lu QD, Zhao YM, Xu YY, Mei H, Shi L, Yuan K, Han Y, Deng JH, Sun YK, Meng SQ, Jiang ZD, Zeng N, Que JY, Zheng YB, Yang BN, Gong YM, Ravindran AV, Kosten T, Wing YK, Tang XD, Yuan JL, Wu P, Shi J, Bao YP, Lu L. Mental and neurological disorders and risk of COVID-19 susceptibility, illness severity and mortality: A systematic review, meta-analysis and call for action. EClinicalMedicine. 2021 Oct; 40:101111. PMID: 34514362; PMCID: PMC8424080.
      Citations: 22     
    55. Yammine L, Green CE, Kosten TR, de Dios C, Suchting R, Lane SD, Verrico CD, Schmitz JM. Exenatide Adjunct to Nicotine Patch Facilitates Smoking Cessation and May Reduce Post-Cessation Weight Gain: A Pilot Randomized Controlled Trial. Nicotine Tob Res. 2021 08 29; 23(10):1682-1690. PMID: 33831213; PMCID: PMC8517504.
      Citations: 2     Fields:    Translation:Humans
    56. Shi L, Lu ZA, Que JY, Huang XL, Lu QD, Liu L, Zheng YB, Liu WJ, Ran MS, Yuan K, Yan W, Sun YK, Sun SW, Shi J, Kosten T, Bao YP, Lu L. Long-Term Impact of COVID-19 on Mental Health among the General Public: A Nationwide Longitudinal Study in China. Int J Environ Res Public Health. 2021 08 20; 18(16). PMID: 34444539; PMCID: PMC8393580.
      Citations: 9     Fields:    Translation:HumansCells
    57. Swann AC, Graham DP, Wilkinson AV, Kosten TR. Nicotine Inhalation and Suicide: Clinical Correlates and Behavioral Mechanisms. Am J Addict. 2021 07; 30(4):316-329. PMID: 34109688.
      Citations: 1     Fields:    Translation:Humans
    58. Thomas PS, Nielsen EM, Spellicy CJ, Harding MJ, Ye A, Patriquin M, Hamon SC, Kosten TR, Nielsen DA. The OPRD1 rs678849 variant influences outcome of disulfiram treatment for cocaine dependency in methadone-maintained patients. Psychiatr Genet. 2021 06 01; 31(3):88-94. PMID: 33953123; PMCID: PMC8108700.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    59. Kosten TR, Petrakis IL. The Hidden Epidemic of Opioid Overdoses During the Coronavirus Disease 2019 Pandemic. JAMA Psychiatry. 2021 06 01; 78(6):585-586. PMID: 33377967.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    60. Stone AE, Scheuermann SE, Haile CN, Cuny GD, Velasquez ML, Linhuber JP, Duddupudi AL, Vigliaturo JR, Pravetoni M, Kosten TA, Kosten TR, Norton EB. Fentanyl conjugate vaccine by injected or mucosal delivery with dmLT or LTA1 adjuvants implicates IgA in protection from drug challenge. NPJ Vaccines. 2021 May 13; 6(1):69. PMID: 33986280; PMCID: PMC8119695.
      Citations: 1     
    61. Morice C, Baker DG, Patel MM, Nolen TL, Nowak K, Hirsch S, Kosten TR, Verrico CD. A randomized trial of safety and pharmacodynamic interactions between a selective glucocorticoid receptor antagonist, PT150, and ethanol in healthy volunteers. Sci Rep. 2021 05 10; 11(1):9876. PMID: 33972573; PMCID: PMC8111026.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    62. Kosten TR, Domingo CB. 2020 Year in Review: A Look Back With an Eye Toward the Future. Am J Addict. 2021 05; 30(3):217-218. PMID: 34057783.
      Citations:    Fields:    
    63. Li YY, Sun Y, Meng SQ, Bao YP, Cheng JL, Chang XW, Ran MS, Sun YK, Kosten T, Strang J, Lu L, Shi J. Internet Addiction Increases in the General Population During COVID-19: Evidence From China. Am J Addict. 2021 07; 30(4):389-397. PMID: 33738888; PMCID: PMC8251395.
      Citations: 12     Fields:    Translation:HumansCellsPHPublic Health
    64. Bigdeli TB, Fanous AH, Li Y, Rajeevan N, Sayward F, Genovese G, Gupta R, Radhakrishnan K, Malhotra AK, Sun N, Lu Q, Hu Y, Li B, Chen Q, Mane S, Miller P, Cheung KH, Gur RE, Greenwood TA, Braff DL, Consortium on the Genetics of Schizophrenia (COGS), Achtyes ED, Buckley PF, Escamilla MA, Lehrer D, Malaspina DP, McCarroll SA, Rapaport MH, Vawter MP, Pato MT, Pato CN, Genomic Psychiatry Cohort (GPC) Investigators, Zhao H, Kosten TR, Brophy M, Pyarajan S, Shi Y, O'Leary TJ, Gleason T, Przygodzki R, Muralidhar S, Gaziano JM, Million Veteran Program (MVP), Huang GD, Concato J, Siever LJ, Aslan M, Harvey PD. Genome-Wide Association Studies of Schizophrenia and Bipolar Disorder in a Diverse Cohort of US Veterans. Schizophr Bull. 2021 03 16; 47(2):517-529. PMID: 33169155; PMCID: PMC7965063.
      Citations: 4     Fields:    Translation:Humans
    65. Zhao Y, Jiang Z, Guo S, Wu P, Lu Q, Xu Y, Liu L, Su S, Shi L, Que J, Sun Y, Sun Y, Deng J, Meng S, Yan W, Yuan K, Sun S, Yang L, Ran M, Kosten TR, Strang J, Lu Y, Huang G, Lu L, Bao Y, Shi J. Association of Symptoms of Attention Deficit and Hyperactivity with Problematic Internet Use among University Students in Wuhan, China During the COVID-19 Pandemic. J Affect Disord. 2021 05 01; 286:220-227. PMID: 33740639; PMCID: PMC9754790.
      Citations: 9     Fields:    Translation:HumansCellsPHPublic Health
    66. Xiu MH, Lang X, Chen DC, Cao B, Kosten TR, Cho RY, Shi H, Wei CW, Wu AS, Zhang XY. Cognitive Deficits and Clinical Symptoms with Hippocampal Subfields in First-Episode and Never-Treated Patients with Schizophrenia. Cereb Cortex. 2021 01 01; 31(1):89-96. PMID: 32901269.
      Citations: 3     Fields:    Translation:Humans
    67. Oh H, Gosnell S, Nguyen T, Tran T, Kosten TR, Salas R. Cingulate Cortex Structural Alterations in Substance Use Disorder Psychiatric Inpatients. Am J Addict. 2021 01; 30(1):72-79. PMID: 33232571.
      Citations: 2     Fields:    Translation:Humans
    68. Yue JL, Yan W, Sun YK, Yuan K, Su SZ, Han Y, Ravindran AV, Kosten T, Everall I, Davey CG, Bullmore E, Kawakami N, Barbui C, Thornicroft G, Lund C, Lin X, Liu L, Shi L, Shi J, Ran MS, Bao YP, Lu L. Mental health services for infectious disease outbreaks including COVID-19: a rapid systematic review. Psychol Med. 2020 11; 50(15):2498-2513. PMID: 33148347; PMCID: PMC7642960.
      Citations: 14     Fields:    Translation:HumansPHPublic Health
    69. Kosten TR, Frances R, Domingo CB. Evolution of the Journal of the American Academy of Addiction Psychiatry: The American Journal on Addictions. Am J Addict. 2020 09; 29(5):375-377. PMID: 32902044.
      Citations:    Fields:    
    70. Kosten T, Aharonovich E, Nangia N, Zavod A, Akerman SC, Lopez-Bresnahan M, Sullivan MA. Cognitive performance of patients with opioid use disorder transitioned to extended-release injectable naltrexone from buprenorphine: Post hoc analysis of exploratory results of a phase 3 randomized controlled trial. Addict Behav. 2020 12; 111:106538. PMID: 32777606.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    71. Sun Y, Li Y, Bao Y, Meng S, Sun Y, Schumann G, Kosten T, Strang J, Lu L, Shi J. Brief Report: Increased Addictive Internet and Substance Use Behavior During the COVID-19 Pandemic in China. Am J Addict. 2020 07; 29(4):268-270. PMID: 32500608; PMCID: PMC7300868.
      Citations: 115     Fields:    Translation:HumansCellsPHPublic Health
    72. Du X, Yin M, Yuan L, Zhang G, Fan Y, Li Z, Yuan N, Lv X, Zhao X, Zou S, Deng W, Kosten TR, Zhang XY. Reduction of depression-like behavior in rat model induced by ShRNA targeting norepinephrine transporter in locus coeruleus. Transl Psychiatry. 2020 05 04; 10(1):130. PMID: 32366842; PMCID: PMC7198598.
      Citations: 4     Fields:    Translation:Animals
    73. Kosten TR, Domingo CB. Editorial: The Year in Review Amidst the COVID-19 Crisis. Am J Addict. 2020 05; 29(3):172-173. PMID: 32333701.
      Citations:    Fields:    
    74. Xia L, Liu L, Hong X, Wang D, Wei G, Wang J, Zhou H, Xu H, Tian Y, Dai Q, Wu HE, Chang C, Wang L, Kosten TR, Zhang XY. One-day tropisetron treatment improves cognitive deficits and P50 inhibition deficits in schizophrenia. Neuropsychopharmacology. 2020 07; 45(8):1362-1368. PMID: 32349117; PMCID: PMC7297960.
      Citations: 3     Fields:    Translation:Humans
    75. Oh H, Lee J, Gosnell SN, Patriquin M, Kosten T, Salas R. Orbitofrontal, dorsal striatum, and habenula functional connectivity in psychiatric patients with substance use problems. Addict Behav. 2020 09; 108:106457. PMID: 32371303.
      Citations: 1     Fields:    Translation:Humans
    76. Sun Y, Bao Y, Kosten T, Strang J, Shi J, Lu L. Editorial: Challenges to Opioid Use Disorders During COVID-19. Am J Addict. 2020 05; 29(3):174-175. PMID: 32281130; PMCID: PMC7262307.
      Citations: 32     Fields:    
    77. Poblete GF, Gosnell SN, Meyer M, Fang M, Nguyen T, Patriquin MA, Nielsen D, Kosten T, Salas R. Process genes list: An approach to link genetics and human brain imaging. J Neurosci Methods. 2020 06 01; 339:108695. PMID: 32201351.
      Citations: 1     Fields:    Translation:Humans
    78. Xu A, Kosten TR. Current status of immunotherapies for addiction. Ann N Y Acad Sci. 2021 04; 1489(1):3-16. PMID: 32147860.
      Citations: 3     Fields:    Translation:Humans
    79. Jennings C, Gosnell S, Curtis KN, Kosten T, Salas R. Altered habenula resting state functional connectivity in deprived veteran tobacco smokers: A pilot study. Bull Menninger Clin. 2020; 84(1):21-34. PMID: 31939683.
      Citations:    Fields:    Translation:Humans
    80. Shorter DI, Zhang X, Domingo CB, Nielsen EM, Kosten TR, Nielsen DA. Doxazosin treatment in cocaine use disorder: pharmacogenetic response based on an alpha-1 adrenoreceptor subtype D genetic variant. Am J Drug Alcohol Abuse. 2020; 46(2):184-193. PMID: 31914324.
      Citations: 4     Fields:    Translation:Humans
    81. Mathai DS, Meyer MJ, Storch EA, Kosten TR. The relationship between subjective effects induced by a single dose of ketamine and treatment response in patients with major depressive disorder: A systematic review. J Affect Disord. 2020 03 01; 264:123-129. PMID: 32056741.
      Citations: 14     Fields:    Translation:Humans
    82. Holst M, Mathai DS, Patel MM, Rodgman C, Keller J, Hussain MZ, De La Garza R, Kosten TR, Verrico CD. Use of Guanfacine for Cannabis Use Disorder and Related Symptomology. Am J Addict. 2019 11; 28(6):455-464. PMID: 31483544.
      Citations: 2     Fields:    Translation:Humans
    83. Hermes G, Hyman SM, Fogelman N, Kosten TR, Sinha R. Lofexidine in Combination With Oral Naltrexone for Opioid Use Disorder Relapse Prevention: A Pilot Randomized, Double-Blind, Placebo-Controlled Study. Am J Addict. 2019 11; 28(6):480-488. PMID: 31448846.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    84. Zhang L, Zheng H, Wu R, Kosten TR, Zhang XY, Zhao J. The effect of minocycline on amelioration of cognitive deficits and pro-inflammatory cytokines levels in patients with schizophrenia. Schizophr Res. 2019 10; 212:92-98. PMID: 31416745.
      Citations: 14     Fields:    Translation:HumansCells
    85. Patel B, Kosten TR. Keeping Up with Clinical Advances: Opioid Use Disorder. CNS Spectr. 2019 08; 24(S1):14-24. PMID: 31290386.
      Citations: 1     Fields:    Translation:Humans
    86. Patel B, Kosten TR. Keeping up with clinical advances: opioid use disorder-Addendum. CNS Spectr. 2019 08; 24(S1):83. PMID: 31482775.
      Citations:    Fields:    
    87. Curtis K, Stewart CJ, Robinson M, Molfese DL, Gosnell SN, Kosten TR, Petrosino JF, De La Garza R, Salas R. Insular resting state functional connectivity is associated with gut microbiota diversity. Eur J Neurosci. 2019 08; 50(3):2446-2452. PMID: 30554441; PMCID: PMC6697239.
      Citations: 13     Fields:    Translation:Humans
    88. Kampangkaew JP, Spellicy CJ, Nielsen EM, Harding MJ, Ye A, Hamon SC, Kosten TR, Nielsen DA. Pharmacogenetic role of dopamine transporter (SLC6A3) variation on response to disulfiram treatment for cocaine addiction. Am J Addict. 2019 07; 28(4):311-317. PMID: 31087723; PMCID: PMC6591035.
      Citations: 4     Fields:    Translation:HumansCells
    89. Kosten TR, Domingo C. Editorial: Continuing the Partnership of AJA With the AAAP. Am J Addict. 2019 05; 28(3):148-149. PMID: 31095826.
      Citations:    Fields:    
    90. Deng H, Desai PV, Mohite S, Okusaga OO, Zhang XY, Nielsen DA, Kosten TR. Hospital Stay in Synthetic Cannabinoid Users With Bipolar Disorder, Schizophrenia, or Other Psychotic Disorders Compared With Cannabis Users. J Stud Alcohol Drugs. 2019 03; 80(2):230-235. PMID: 31014468; PMCID: PMC6489549.
      Citations: 1     Fields:    Translation:Humans
    91. Yang F, Kosten TR. Psychopharmacology: neuroimmune signaling in psychiatric disease-developing vaccines against abused drugs using toll-like receptor agonists. Psychopharmacology (Berl). 2019 Oct; 236(10):2899-2907. PMID: 30726515.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    92. Yammine L, Kosten TR, Pimenova M, Schmitz JM. Cigarette smoking, type 2 diabetes mellitus, and glucagon-like peptide-1 receptor agonists as a potential treatment for smokers with diabetes: An integrative review. Diabetes Res Clin Pract. 2019 Mar; 149:78-88. PMID: 30735771.
      Citations: 2     Fields:    Translation:Humans
    93. Kosten TR, Baxter LE. Review article: Effective management of opioid withdrawal symptoms: A gateway to opioid dependence treatment. Am J Addict. 2019 02; 28(2):55-62. PMID: 30701615; PMCID: PMC6590307.
      Citations: 30     Fields:    Translation:HumansPHPublic Health
    94. Arora R, Haile CN, Kosten TA, Wu Y, Ramakrishnan M, Hawkins LD, Orson FM, Kosten TR. Preclinical efficacy of an anti-methamphetamine vaccine using E6020 adjuvant. Am J Addict. 2019 02; 28(2):119-126. PMID: 30701618.
      Citations: 6     Fields:    Translation:Animals
    95. Lake EP, Mitchell BG, Shorter DI, Kosten T, Domingo CB, Walder AM. Buprenorphine for the treatment of posttraumatic stress disorder. Am J Addict. 2019 02; 28(2):86-91. PMID: 30664299.
      Citations: 4     Fields:    Translation:Humans
    96. Patel MM, Nielsen DA, Kosten TR, De La Garza R, Newton TF, Verrico CD. FAAH variant Pro129Thr modulates subjective effects produced by cocaine administration. Am J Addict. 2018 10; 27(7):567-573. PMID: 30126012.
      Citations: 5     Fields:    Translation:Humans
    97. Deng H, Verrico CD, Kosten TR, Nielsen DA. Psychosis and synthetic cannabinoids. Psychiatry Res. 2018 10; 268:400-412. PMID: 30125871.
      Citations: 11     Fields:    Translation:HumansAnimals
    98. Carroll FI, Kosten TR, Buda JJ, Wang L, Walters BB. A Double-Blind, Placebo-Controlled Trial Demonstrating the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of RTI-336. Front Pharmacol. 2018; 9:712. PMID: 30042675; PMCID: PMC6048956.
      Citations: 1     
    99. Kosten TR, Graham DP, Nielsen DA. Opioid Use Disorder After Self-medicating Pain From Traumatic Brain Injury. JAMA Psychiatry. 2018 06 01; 75(6):649-650. PMID: 29710138.
      Citations: 1     Fields:    Translation:Humans
    100. Kosten TR, Graham DP, Nielsen DA. Neurobiology of Opioid Use Disorder and Comorbid Traumatic Brain Injury. JAMA Psychiatry. 2018 06 01; 75(6):642-648. PMID: 29710079.
      Citations:    Fields:    Translation:Humans
    101. Kosten TR, Domingo C. Editorial: A new partnership with the AAAP newsletter. Am J Addict. 2018 06; 27(4):257-258. PMID: 29873860.
      Citations:    Fields:    
    102. Zhang L, Zheng H, Wu R, Zhu F, Kosten TR, Zhang XY, Zhao J. Minocycline adjunctive treatment to risperidone for negative symptoms in schizophrenia: Association with pro-inflammatory cytokine levels. Prog Neuropsychopharmacol Biol Psychiatry. 2018 07 13; 85:69-76. PMID: 29678772.
      Citations: 15     Fields:    Translation:Humans
    103. Bisaga A, Mannelli P, Yu M, Nangia N, Graham CE, Tompkins DA, Kosten TR, Akerman SC, Silverman BL, Sullivan MA. Outpatient transition to extended-release injectable naltrexone for patients with opioid use disorder: A phase 3 randomized trial. Drug Alcohol Depend. 2018 06 01; 187:171-178. PMID: 29674251.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    104. Kosten T, Domingo C. Commentary. Am J Addict. 2018 Apr; 27(3):157. PMID: 29596723.
      Citations:    Fields:    
    105. Bisaga A, Mannelli P, Sullivan MA, Vosburg SK, Compton P, Woody GE, Kosten TR. Antagonists in the medical management of opioid use disorders: Historical and existing treatment strategies. Am J Addict. 2018 04; 27(3):177-187. PMID: 29596725; PMCID: PMC5900907.
      Citations: 12     Fields:    Translation:Humans
    106. Zhang X, Nielsen DA, Domingo CB, Shorter DI, Nielsen EM, Kosten TR. Pharmacogenetics of Dopamine ?-Hydroxylase in cocaine dependence therapy with doxazosin. Addict Biol. 2019 05; 24(3):531-538. PMID: 29498170; PMCID: PMC6119656.
      Citations: 4     Fields:    Translation:Humans
    107. Yammine L, Kosten TR, Cinciripini PM, Green CE, Meininger JC, Minnix JA, Newton TF. Exenatide once weekly for smoking cessation: study protocol for a randomized clinical trial. Medicine (Baltimore). 2018 Jan; 97(2):e9567. PMID: 29480848; PMCID: PMC5943874.
      Citations: 5     Fields:    Translation:Humans
    108. Kosten TR, Domingo C. Editorial. Am J Addict. 2018 Jan; 27(1):5-6. PMID: 29283478.
      Citations:    Fields:    
    109. Bashiri M, Mancino MJ, Stanick VA, Thostenson J, Kosten TR, Oliveto AH. Moderators of response to sertraline versus placebo among recently abstinent, cocaine dependent patients: A retrospective analysis of two clinical trials. Am J Addict. 2017 Dec; 26(8):807-814. PMID: 29115703; PMCID: PMC5699965.
      Citations: 2     Fields:    Translation:Humans
    110. Ma L, Steinberg JL, Cunningham KA, Bjork JM, Lane SD, Schmitz JM, Burroughs T, Narayana PA, Kosten TR, Bechara A, Moeller FG. Altered anterior cingulate cortex to hippocampus effective connectivity in response to drug cues in men with cocaine use disorder. Psychiatry Res Neuroimaging. 2018 01 30; 271:59-66. PMID: 29108734; PMCID: PMC5741507.
      Citations: 9     Fields:    Translation:Humans
    111. Shorter D, Hsieh J, Kosten TR. Pharmacologic Management of Comorbid Post-Traumatic Stress Disorder and Addictions. Focus (Am Psychiatr Publ). 2017 Oct; 15(4):454-461. PMID: 32015701; PMCID: PMC6519540.
      Citations:    
    112. Heekin RD, Shorter D, Kosten TR. Current status and future prospects for the development of substance abuse vaccines. Expert Rev Vaccines. 2017 11; 16(11):1067-1077. PMID: 28918668.
      Citations: 10     Fields:    Translation:Humans
    113. Curtis K, Viswanath H, Velasquez KM, Molfese DL, Harding MJ, Aramayo E, Baldwin PR, Ambrosi E, Madan A, Patriquin M, Frueh BC, Fowler JC, Kosten TR, Nielsen DA, Salas R. Increased habenular connectivity in opioid users is associated with an a5 subunit nicotinic receptor genetic variant. Am J Addict. 2017 Oct; 26(7):751-759. PMID: 28857330; PMCID: PMC5745069.
      Citations: 8     Fields:    Translation:Humans
    114. Mathai DS, Holst M, Rodgman C, Haile CN, Keller J, Hussain MZ, Kosten TR, Newton TF, Verrico CD. Guanfacine Attenuates Adverse Effects of Dronabinol (THC) on Working Memory in Adolescent-Onset Heavy Cannabis Users: A Pilot Study. J Neuropsychiatry Clin Neurosci. 2018; 30(1):66-76. PMID: 28641496.
      Citations: 2     Fields:    Translation:Humans
    115. Zhao RJ, Sun W, Zhang LL, Bao YP, Huang L, Dong P, Zhou SJ, Wang ZQ, Kosten TR, Sun HQ. Psychopathology and personality traits associated with driving while intoxicated in Beijing, China: Implications for interventions. Am J Addict. 2017 Jun; 26(4):374-378. PMID: 28342226.
      Citations: 1     Fields:    Translation:Humans
    116. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 24112143; PMCID: PMC5356691.
      Citations:    
    117. Ayanga D, Shorter D, Kosten TR. Update on pharmacotherapy for treatment of opioid use disorder. Expert Opin Pharmacother. 2016 Dec; 17(17):2307-2318. PMID: 27734745.
      Citations: 23     Fields:    Translation:Humans
    118. Mathai DS, Verrico CD, Shorter D, Coverdale JH, Kosten TR. "Just one bad high:" considering synthetic cannabinoid outcome expectancies in adolescents. Am J Addict. 2016 12; 25(8):620-622. PMID: 27749024.
      Citations:    Fields:    
    119. Shorter D, Nielsen DA, Hamon SC, Nielsen EM, Kosten TR, Newton TF, De La Garza R. The a-1 adrenoceptor (ADRA1A) genotype moderates the magnitude of acute cocaine-induced subjective effects in cocaine-dependent individuals. Pharmacogenet Genomics. 2016 09; 26(9):428-35. PMID: 27379509; PMCID: PMC4970930.
      Citations: 2     Fields:    Translation:Humans
    120. Verrico CD, Haile CN, De La Garza R, Grasing K, Kosten TR, Newton TF. Subjective and Cardiovascular Effects of Intravenous Methamphetamine during Perindopril Maintenance: A Randomized, Double-Blind, Placebo-Controlled Human Laboratory Study. Int J Neuropsychopharmacol. 2016 07; 19(7). PMID: 27207905; PMCID: PMC4966279.
      Citations: 5     Fields:    Translation:Humans
    121. Kosten TR, Domingo C. Editorial. Am J Addict. 2016 06; 25(4):252-3. PMID: 27232764.
      Citations:    Fields:    
    122. Li X, Shorter D, Kosten TR. Buprenorphine Prescribing: To Expand or Not to Expand. J Psychiatr Pract. 2016 05; 22(3):183-92. PMID: 27123798; PMCID: PMC4852384.
      Citations: 4     Fields:    Translation:Humans
    123. Kosten TR. An Opioid for Depression? Am J Psychiatry. 2016 05 01; 173(5):446-7. PMID: 27133402.
      Citations: 3     Fields:    Translation:Humans
    124. Gao Y, Zhou JJ, Zhu Y, Kosten T, Li DP. Chronic Unpredictable Mild Stress Induces Loss of GABA Inhibition in Corticotrophin-Releasing Hormone-Expressing Neurons through NKCC1 Upregulation. Neuroendocrinology. 2017; 104(2):194-208. PMID: 27077366; PMCID: PMC5065755.
      Citations: 20     Fields:    Translation:AnimalsCells
    125. An HM, Tan YL, Tan SP, Shi J, Wang ZR, Yang FD, Huang XF, Soars JC, Kosten TR, Zhang XY. Smoking and Serum Lipid Profiles in Schizophrenia. Neurosci Bull. 2016 Aug; 32(4):383-8. PMID: 27017941; PMCID: PMC5563778.
      Citations: 11     Fields:    Translation:Humans
    126. Xiu MH, Tian L, Chen S, Tan YL, Chen DC, Chen J, Chen N, De Yang F, Licinio J, Kosten TR, Soares JC, Zhang XY. Contribution of IL-10 and its -592 A/C polymorphism to cognitive functions in first-episode drug-naive schizophrenia. Brain Behav Immun. 2016 Oct; 57:116-124. PMID: 26971470.
      Citations: 13     Fields:    Translation:Humans
    127. Zhang XY, Tan YL, Chen DC, Tan SP, Malouta MZ, Bernard JD, Combs JL, Bhatti S, Davis MC, Kosten TR, Soares JC. Serum IL-18 level, clinical symptoms and IL-18-607A/C polymorphism among chronic patients with schizophrenia in a Chinese Han population. Psychoneuroendocrinology. 2016 06; 68:140-7. PMID: 26974498.
      Citations: 1     Fields:    Translation:HumansCells
    128. Zhang XY, Fan FM, Chen DC, Tan YL, Tan SP, Hu K, Salas R, Kosten TR, Zunta-Soares G, Soares JC. Extensive white matter abnormalities and clinical symptoms in drug-naive patients with first-episode schizophrenia: a voxel-based diffusion tensor imaging study. J Clin Psychiatry. 2016 Feb; 77(2):205-11. PMID: 26761708.
      Citations: 16     Fields:    Translation:Humans
    129. Deng H, Wang J, Zhang X, Ma M, Domingo C, Sun H, Kosten T. Smoking reduction and quality of life in chronic patients with schizophrenia in a Chinese population--A pilot study. Am J Addict. 2016 Mar; 25(2):86-90. PMID: 26824336.
      Citations: 2     Fields:    Translation:Humans
    130. Sharp C, Fowler JC, Salas R, Nielsen D, Allen J, Oldham J, Kosten T, Mathew S, Madan A, Frueh BC, Fonagy P. Operationalizing NIMH Research Domain Criteria (RDoC) in naturalistic clinical settings. Bull Menninger Clin. 2016; 80(3):187-212. PMID: 27583809.
      Citations: 2     Fields:    Translation:Humans
    131. Li X, Kosten T. Treating Addiction to Prescription Opioids. S D Med. 2016 Spec; No:64-67. PMID: 28817853.
      Citations:    Fields:    
    132. Christodoulides N, De La Garza R, Simmons GW, McRae MP, Wong J, Newton TF, Kosten TR, Haque A, McDevitt JT. Next Generation Programmable Bio-Nano-Chip System for On-Site Detection in Oral Fluids. J Drug Abuse. 2015 Nov 23; 1(1):1-6. PMID: 26925466; PMCID: PMC4765139.
      Citations: 2     
    133. Shorter D, Hsieh J, Kosten TR. Pharmacologic management of comorbid post-traumatic stress disorder and addictions. Am J Addict. 2015 Dec; 24(8):705-12. PMID: 26587796.
      Citations: 21     Fields:    Translation:Humans
    134. Haile CN, Kosten TA, Shen XY, O'Malley PW, Winoske KJ, Kinsey BM, Wu Y, Huang Z, Lykissa ED, Naidu N, Cox JA, Arora R, Kosten TR, Orson FM. Altered methamphetamine place conditioning in mice vaccinated with a succinyl-methamphetamine-tetanus-toxoid vaccine. Am J Addict. 2015 Dec; 24(8):748-55. PMID: 26584468.
      Citations: 10     Fields:    Translation:AnimalsPHPublic Health
    135. Zhang XY, Tan YL, Chen DC, Tan SP, Yang FD, Wu HE, Zunta-Soares GB, Huang XF, Kosten TR, Soares JC. Interaction of BDNF with cytokines in chronic schizophrenia. Brain Behav Immun. 2016 Jan; 51:169-175. PMID: 26407757.
      Citations: 13     Fields:    Translation:Humans
    136. Newton TF, Haile CN, Mahoney JJ, Shah R, Verrico CD, De La Garza R, Kosten TR. Dopamine D3 receptor-preferring agonist enhances the subjective effects of cocaine in humans. Psychiatry Res. 2015 Nov 30; 230(1):44-9. PMID: 26239766; PMCID: PMC4584195.
      Citations: 2     Fields:    Translation:Humans
    137. Brewer AJ, Nielsen DA, Spellicy CJ, Hamon SC, Gingrich J, Thompson-Lake DG, Nielsen EM, Mahoney JJ, Kosten TR, Newton TF, De La Garza R. Genetic variation of the dopamine transporter (DAT1) influences the acute subjective responses to cocaine in volunteers with cocaine use disorders. Pharmacogenet Genomics. 2015 Jun; 25(6):296-304. PMID: 25850966; PMCID: PMC4414865.
      Citations: 11     Fields:    Translation:Humans
    138. Christodoulides N, De La Garza R, Simmons GW, McRae MP, Wong J, Newton TF, Smith R, Mahoney JJ, Hohenstein J, Gomez S, Floriano PN, Talavera H, Sloan DJ, Moody DE, Andrenyak DM, Kosten TR, Haque A, McDevitt JT. Application of programmable bio-nano-chip system for the quantitative detection of drugs of abuse in oral fluids. Drug Alcohol Depend. 2015 08 01; 153:306-13. PMID: 26048639; PMCID: PMC4509839.
      Citations: 11     Fields:    Translation:HumansPHPublic Health
    139. Ma L, Steinberg JL, Cunningham KA, Lane SD, Bjork JM, Neelakantan H, Price AE, Narayana PA, Kosten TR, Bechara A, Moeller FG. Inhibitory behavioral control: A stochastic dynamic causal modeling study comparing cocaine dependent subjects and controls. Neuroimage Clin. 2015; 7:837-47. PMID: 26082893; PMCID: PMC4459041.
      Citations: 20     Fields:    Translation:Humans
    140. Sun Y, Zhao LY, Wang GB, Yue WH, He Y, Shu N, Lin QX, Wang F, Li JL, Chen N, Wang HM, Kosten TR, Feng JJ, Wang J, Tang YD, Liu SX, Deng GF, Diao GH, Tan YL, Han HB, Lin L, Shi J. ZNF804A variants confer risk for heroin addiction and affect decision making and gray matter volume in heroin abusers. Addict Biol. 2016 May; 21(3):657-66. PMID: 25708696.
      Citations: 7     Fields:    Translation:Humans
    141. Cui Y, Robinson JD, Engelmann JM, Lam CY, Minnix JA, Karam-Hage M, Wetter DW, Dani JA, Kosten TR, Cinciripini PM. Reinforcement sensitivity underlying treatment-seeking smokers' affect, smoking reinforcement motives, and affective responses. Psychol Addict Behav. 2015 Jun; 29(2):300-311. PMID: 25621416; PMCID: PMC4469611.
      Citations: 4     Fields:    Translation:Humans
    142. Buda JJ, Carroll FI, Kosten TR, Swearingen D, Walters BB. A Double-Blind, Placebo-Controlled Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of JDTic. Neuropsychopharmacology. 2015 Aug; 40(9):2059-65. PMID: 25628006; PMCID: PMC4613600.
      Citations: 26     Fields:    Translation:Humans
    143. Li QQ, Sun CY, Luo YX, Xue YX, Meng SQ, Xu LZ, Chen N, Deng JH, Zhai HF, Kosten TR, Shi J, Lu L, Sun HQ. A conjugate vaccine attenuates morphine- and heroin-induced behavior in rats. Int J Neuropsychopharmacol. 2014 Dec 07; 18(5). PMID: 25522425; PMCID: PMC4376548.
      Citations: 11     Fields:    Translation:Animals
    144. Thompson-Lake DG, Cooper KN, Mahoney JJ, Bordnick PS, Salas R, Kosten TR, Dani JA, De La Garza R. Withdrawal Symptoms and Nicotine Dependence Severity Predict Virtual Reality Craving in Cigarette-Deprived Smokers. Nicotine Tob Res. 2015 Jul; 17(7):796-802. PMID: 25475087; PMCID: PMC4542676.
      Citations: 12     Fields:    Translation:Humans
    145. Shorter D, Domingo CB, Kosten TR. Emerging drugs for the treatment of cocaine use disorder: a review of neurobiological targets and pharmacotherapy. Expert Opin Emerg Drugs. 2015 Mar; 20(1):15-29. PMID: 25425416.
      Citations: 29     Fields:    Translation:HumansAnimals
    146. Ma L, Steinberg JL, Cunningham KA, Lane SD, Kramer LA, Narayana PA, Kosten TR, Bechara A, Moeller FG. Inhibitory behavioral control: a stochastic dynamic causal modeling study using network discovery analysis. Brain Connect. 2015 Apr; 5(3):177-86. PMID: 25336321; PMCID: PMC4394161.
      Citations: 10     Fields:    Translation:Humans
    147. Kosten TA, Shen XY, Kinsey BM, Kosten TR, Orson FM. Attenuation of cocaine-induced locomotor activity in male and female mice by active immunization. Am J Addict. 2014 Nov-Dec; 23(6):604-7. PMID: 25251469; PMCID: PMC4184912.
      Citations: 4     Fields:    Translation:AnimalsPHPublic Health
    148. Li X, Shorter D, Kosten TR. Buprenorphine in the treatment of opioid addiction: opportunities, challenges and strategies. Expert Opin Pharmacother. 2014 Oct; 15(15):2263-75. PMID: 25171726.
      Citations: 12     Fields:    Translation:Humans
    149. Graham DP, Nielsen DA, Kosten TR, Davis LL, Hamner MB, Makotkine I, Yehuda R. Examining the utility of using genotype and functional biology in a clinical pharmacology trial: pilot testing dopamine ?-hydroxylase, norepinephrine, and post-traumatic stress disorder. Psychiatr Genet. 2014 Aug; 24(4):181-2. PMID: 24983834; PMCID: PMC4080201.
      Citations: 4     Fields:    Translation:Humans
    150. Ramakrishnan M, Kinsey BM, Singh RA, Kosten TR, Orson FM. Hapten optimization for cocaine vaccine with improved cocaine recognition. Chem Biol Drug Des. 2014 Sep; 84(3):354-63. PMID: 24803171; PMCID: PMC4127111.
      Citations: 7     Fields:    Translation:Animals
    151. Liu S, Green CE, Lane SD, Kosten TR, Moeller FG, Nielsen DA, Schmitz JM. The influence of dopamine ?-hydroxylase gene polymorphism rs1611115 on levodopa/carbidopa treatment for cocaine dependence: a preliminary study. Pharmacogenet Genomics. 2014 Jul; 24(7):370-3. PMID: 24809448.
      Citations: 10     Fields:    Translation:Humans
    152. Orson FM, Wang R, Brimijoin S, Kinsey BM, Singh RA, Ramakrishnan M, Wang HY, Kosten TR. The future potential for cocaine vaccines. Expert Opin Biol Ther. 2014 Sep; 14(9):1271-83. PMID: 24835496; PMCID: PMC4154474.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    153. Sun HQ, Chen HM, Yang FD, Lu L, Kosten TR. Epidemiological trends and the advances of treatments of amphetamine-type stimulants (ATS) in China. Am J Addict. 2014 May-Jun; 23(3):313-7. PMID: 24724890.
      Citations: 7     Fields:    Translation:HumansAnimals
    154. Kosten TR, Domingo CB, Shorter D, Orson F, Green C, Somoza E, Sekerka R, Levin FR, Mariani JJ, Stitzer M, Tompkins DA, Rotrosen J, Thakkar V, Smoak B, Kampman K. Vaccine for cocaine dependence: a randomized double-blind placebo-controlled efficacy trial. Drug Alcohol Depend. 2014 Jul 01; 140:42-7. PMID: 24793366; PMCID: PMC4073297.
      Citations: 46     Fields:    Translation:HumansPHPublic Health
    155. McGaugh J, Chopra MP, Guise JB, Cargile C, Williams DK, Thostenson J, Kosten TR, Sanders N, Oliveto A, Mancino MJ. Clinical efficacy of sertraline alone and augmented with gabapentin in recently abstinent cocaine-dependent patients with depressive symptoms. J Clin Psychopharmacol. 2014 Apr; 34(2):234-9. PMID: 24525654; PMCID: PMC4068618.
      Citations: 13     Fields:    Translation:Humans
    156. Kosten T, Domingo C, Orson F, Kinsey B. Vaccines against stimulants: cocaine and MA. Br J Clin Pharmacol. 2014 Feb; 77(2):368-74. PMID: 23509915; PMCID: PMC4014030.
      Citations: 23     Fields:    Translation:HumansAnimals
    157. Schottenfeld RS, Chawarski MC, Cubells JF, George TP, Lappalainen J, Kosten TR. Randomized clinical trial of disulfiram for cocaine dependence or abuse during buprenorphine treatment. Drug Alcohol Depend. 2014 Mar 01; 136:36-42. PMID: 24462581.
      Citations: 14     Fields:    Translation:Humans
    158. Nielsen DA, Hamon SC, Kosten TR. The ?-opioid receptor gene as a predictor of response in a cocaine vaccine clinical trial. Psychiatr Genet. 2013 Dec; 23(6):225-32. PMID: 23995774; PMCID: PMC3885873.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    159. Haile CN, Kosten TR. Pharmacotherapy for stimulant-related disorders. Curr Psychiatry Rep. 2013 Nov; 15(11):415. PMID: 24142188; PMCID: PMC3858902.
      Citations: 9     Fields:    Translation:Humans
    160. An HM, Tan YL, Shi J, Wang ZR, Li J, Wang YC, Kosten TR, Zhou DF, Yang FD, Zhang XY. Extract of Ginkgo biloba is equivalent to vitamin E in attenuating and preventing vacuous chewing movements in a rat model of tardive dyskinesia. Behav Pharmacol. 2013 Oct; 24(7):610-6. PMID: 23994817.
      Citations: 2     Fields:    Translation:Animals
    161. Verrico CD, Haile CN, Newton TF, Kosten TR, De La Garza R, De La Garza R. Pharmacotherapeutics for substance-use disorders: a focus on dopaminergic medications. Expert Opin Investig Drugs. 2013 Dec; 22(12):1549-68. PMID: 24033127; PMCID: PMC4422382.
      Citations: 19     Fields:    Translation:HumansAnimals
    162. Zhang XY, Chen DC, Tan YL, Xiu MH, Cui J, Hui L, Yang FD, Kosten TR. Socio-demographic and clinical characteristics of heavy and non-heavy smokers among schizophrenia inpatients in a Chinese Han population. Psychopharmacology (Berl). 2014 Jan; 231(1):305-14. PMID: 23963531.
      Citations: 5     Fields:    Translation:Humans
    163. Sun H, Wang F, Fan H, Yan Q, Cui K, Yuan W, Zhao F, Zhao L, Yuan J, Yang F, Kosten TR, Zhang XY. The interaction of polymorphisms of IL10 and DBH was associated with general symptoms of PANSS with TD in Chinese Han schizophrenic patients. PLoS One. 2013; 8(8):e70963. PMID: 23951054; PMCID: PMC3737228.
      Citations: 6     Fields:    Translation:HumansCells
    164. Li W, Zhou N, Yu Q, Li X, Yu Y, Sun S, Kou C, Chen DC, Xiu MH, Kosten TR, Zhang XY. Association of BDNF gene polymorphisms with schizophrenia and clinical symptoms in a Chinese population. Am J Med Genet B Neuropsychiatr Genet. 2013 Sep; 162B(6):538-45. PMID: 23832605.
      Citations: 7     Fields:    Translation:Humans
    165. Wu JQ, Chen DC, Xiu MH, Tan YL, Yang FD, Kosten TR, Zhang XY. Tardive dyskinesia is associated with greater cognitive impairment in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Oct 01; 46:71-7. PMID: 23827756.
      Citations: 6     Fields:    Translation:Humans
    166. Spellicy CJ, Kosten TR, Hamon SC, Harding MJ, Nielsen DA. ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse. Pharmacogenet Genomics. 2013 Jul; 23(7):333-40. PMID: 23635803; PMCID: PMC5396392.
      Citations: 12     Fields:    Translation:Humans
    167. Zhang XY, Al Jurdi RK, Zoghbi AW, Chen DC, Xiu MH, Tan YL, Yang FD, Kosten TR. Prevalence, demographic and clinical correlates of suicide attempts in Chinese medicated chronic inpatients with schizophrenia. J Psychiatr Res. 2013 Oct; 47(10):1370-5. PMID: 23791457.
      Citations: 12     Fields:    Translation:Humans
    168. Han M, Huang XF, Chen DC, Xiu M, Kosten TR, Zhang XY. Diabetes and cognitive deficits in chronic schizophrenia: a case-control study. PLoS One. 2013; 8(6):e66299. PMID: 23840437; PMCID: PMC3688788.
      Citations: 10     Fields:    Translation:Humans
    169. Kosten TA, Shen XY, O'Malley PW, Kinsey BM, Lykissa ED, Orson FM, Kosten TR. A morphine conjugate vaccine attenuates the behavioral effects of morphine in rats. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Aug 01; 45:223-9. PMID: 23739535; PMCID: PMC3773503.
      Citations: 17     Fields:    Translation:Animals
    170. Hui L, Zhang X, Yu YQ, Han M, Huang XF, Chen DC, Wang ZR, Du WL, Kou CG, Yu Q, Kosten TR, Zhang XY. Association between DBH 19 bp insertion/deletion polymorphism and cognition in first-episode schizophrenic patients. Schizophr Res. 2013 Jul; 147(2-3):236-40. PMID: 23707643.
      Citations: 6     Fields:    Translation:HumansCells
    171. Krupitsky E, Zvartau E, Blokhina E, Verbitskaya E, Tsoy M, Wahlgren V, Burakov A, Masalov D, Romanova TN, Palatkin V, Tyurina A, Yaroslavtseva T, Sinha R, Kosten TR. Naltrexone with or without guanfacine for preventing relapse to opiate addiction in St.-Petersburg, Russia. Drug Alcohol Depend. 2013 Oct 01; 132(3):674-80. PMID: 23683793; PMCID: PMC3971535.
      Citations: 16     Fields:    Translation:HumansPHPublic Health
    172. Zhang XY, Chen DC, Xiu MH, Tan YL, Yang FD, Zhang LY, Zhang LY, Haile CN, Kosten TR. Clinical symptoms and cognitive impairment associated with male schizophrenia relate to plasma manganese superoxide dismutase activity: a case-control study. J Psychiatr Res. 2013 Aug; 47(8):1049-53. PMID: 23611682.
      Citations: 8     Fields:    Translation:Humans
    173. Kosten TR, Domingo CB. Can you vaccinate against substance abuse? Expert Opin Biol Ther. 2013 Aug; 13(8):1093-7. PMID: 23594123; PMCID: PMC4154471.
      Citations: 14     Fields:    Translation:HumansPHPublic Health
    174. Zhang XY, Chen DC, Xiu MH, Yang FD, Tan Y, Luo X, Zuo L, Kosten TA, Kosten TR. Cognitive function, plasma MnSOD activity, and MnSOD Ala-9Val polymorphism in patients with schizophrenia and normal controls. Schizophr Bull. 2014 May; 40(3):592-601. PMID: 23588476; PMCID: PMC3984504.
      Citations: 7     Fields:    Translation:Humans
    175. Zhou N, Yu Q, Li X, Yu Y, Kou C, Li W, Xu H, Luo X, Zuo L, Kosten TR, Zhang XY. Association of the dopamine ?-hydroxylase 19 bp insertion/deletion polymorphism with positive symptoms but not tardive dyskinesia in schizophrenia. Hum Psychopharmacol. 2013 May; 28(3):230-7. PMID: 23559427.
      Citations: 5     Fields:    Translation:Humans
    176. Zhang X, Hui L, Liu Y, Wang ZQ, You Y, Miao LN, Sun SL, Guan SL, Xiang Y, Kosten TR, Zhang XY. The type 2 diabetes mellitus susceptibility gene IGF2BP2 is associated with schizophrenia in a Han Chinese population. J Clin Psychiatry. 2013 Apr; 74(4):e287-92. PMID: 23656854.
      Citations: 8     Fields:    Translation:Humans
    177. Zhang XY, Tang W, Xiu MH, Chen DC, Yang FD, Tan YL, Wang ZR, Zhang F, Liu J, Liu L, Chen Y, Wen N, Kosten TR. Interleukin 18 and cognitive impairment in first episode and drug na?ve schizophrenia versus healthy controls. Brain Behav Immun. 2013 Aug; 32:105-11. PMID: 23499732.
      Citations: 14     Fields:    Translation:Humans
    178. Graham DP, Helmer DA, Harding MJ, Kosten TR, Petersen NJ, Nielsen DA. Serotonin transporter genotype and mild traumatic brain injury independently influence resilience and perception of limitations in veterans. J Psychiatr Res. 2013 Jun; 47(6):835-42. PMID: 23478049; PMCID: PMC3643301.
      Citations: 19     Fields:    Translation:Humans
    179. Wu JQ, Kosten TR, Zhang XY. Free radicals, antioxidant defense systems, and schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Oct 01; 46:200-6. PMID: 23470289.
      Citations: 82     Fields:    Translation:HumansAnimalsCells
    180. Brimijoin S, Shen X, Orson F, Kosten T. Prospects, promise and problems on the road to effective vaccines and related therapies for substance abuse. Expert Rev Vaccines. 2013 Mar; 12(3):323-32. PMID: 23496671; PMCID: PMC3738206.
      Citations: 16     Fields:    Translation:Humans
    181. Brown AE, Tonigan JS, Pavlik VN, Kosten TR, Volk RJ. Spirituality and confidence to resist substance use among celebrate recovery participants. J Relig Health. 2013 Mar; 52(1):107-13. PMID: 21246280.
      Citations: 3     Fields:    Translation:Humans
    182. Kosten TR, Domingo CB, Hamon SC, Nielsen DA. DBH gene as predictor of response in a cocaine vaccine clinical trial. Neurosci Lett. 2013 Apr 29; 541:29-33. PMID: 23458673; PMCID: PMC3631430.
      Citations: 11     Fields:    Translation:Humans
    183. Orson FM, Rossen RD, Shen X, Lopez AY, Wu Y, Kosten TR. Spontaneous development of IgM anti-cocaine antibodies in habitual cocaine users: effect on IgG antibody responses to a cocaine cholera toxin B conjugate vaccine. Am J Addict. 2013 Mar-Apr; 22(2):169-74. PMID: 23414504; PMCID: PMC4143984.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    184. Spellicy CJ, Kosten TR, Hamon SC, Harding MJ, Nielsen DA. The MTHFR C677T Variant is Associated with Responsiveness to Disulfiram Treatment for Cocaine Dependency. Front Psychiatry. 2012; 3:109. PMID: 23335901; PMCID: PMC3544007.
      Citations: 3     
    185. Zhang XY, Chen DC, Xiu MH, Luo X, Zuo L, Haile CN, Kosten TA, Kosten TR. BDNF Val66Met variant and smoking in a Chinese population. PLoS One. 2012; 7(12):e53295. PMID: 23285275; PMCID: PMC3532294.
      Citations: 4     Fields:    Translation:Humans
    186. Zhen YF, Zhang J, Liu XY, Fang H, Tian LB, Zhou DH, Kosten TR, Zhang XY. Low BDNF is associated with cognitive deficits in patients with type 2 diabetes. Psychopharmacology (Berl). 2013 May; 227(1):93-100. PMID: 23263460.
      Citations: 36     Fields:    Translation:Humans
    187. Zhang XY, Chen DC, Xiu MH, Yang FD, Tan YL, He S, Kosten TA, Kosten TR. Thioredoxin, a novel oxidative stress marker and cognitive performance in chronic and medicated schizophrenia versus healthy controls. Schizophr Res. 2013 Feb; 143(2-3):301-6. PMID: 23238053.
      Citations: 12     Fields:    Translation:Humans
    188. He J, Xie Y, Tao J, Su H, Wu W, Zou S, Zhang J, Zhang J, Zhang H, Yang X, Guo J, Tang W, Zhang F, Liu J, Liu L, Chen Y, Wen N, Kosten TR, Zhang XY. Gender differences in socio-demographic and clinical characteristics of methamphetamine inpatients in a Chinese population. Drug Alcohol Depend. 2013 Jun 01; 130(1-3):94-100. PMID: 23149112.
      Citations: 17     Fields:    Translation:HumansPHPublic Health
    189. Haile CN, De La Garza R, Mahoney JJ, Nielsen DA, Kosten TR, Newton TF. The impact of disulfiram treatment on the reinforcing effects of cocaine: a randomized clinical trial. PLoS One. 2012; 7(11):e47702. PMID: 23144826; PMCID: PMC3493584.
      Citations: 14     Fields:    Translation:Humans
    190. Cui Y, Versace F, Engelmann JM, Minnix JA, Robinson JD, Lam CY, Karam-Hage M, Brown VL, Wetter DW, Dani JA, Kosten TR, Cinciripini PM. Alpha oscillations in response to affective and cigarette-related stimuli in smokers. Nicotine Tob Res. 2013 May; 15(5):917-24. PMID: 23060019; PMCID: PMC3621581.
      Citations: 10     Fields:    Translation:Humans
    191. Shen XY, Kosten TA, Lopez AY, Kinsey BM, Kosten TR, Orson FM. A vaccine against methamphetamine attenuates its behavioral effects in mice. Drug Alcohol Depend. 2013 Apr 01; 129(1-2):41-8. PMID: 23022610; PMCID: PMC3563850.
      Citations: 27     Fields:    Translation:AnimalsPHPublic Health
    192. Zhang XY, Liu L, Liu S, Hong X, Chen DC, Xiu MH, Yang FD, Zhang Z, Zhang X, Kosten TA, Kosten TR. Short-term tropisetron treatment and cognitive and P50 auditory gating deficits in schizophrenia. Am J Psychiatry. 2012 Sep; 169(9):974-81. PMID: 22952075.
      Citations: 40     Fields:    Translation:Humans
    193. Brimijoin S, Orson F, Kosten TR, Kinsey B, Shen XY, White SJ, Gao Y. Anti-cocaine antibody and butyrylcholinesterase-derived cocaine hydrolase exert cooperative effects on cocaine pharmacokinetics and cocaine-induced locomotor activity in mice. Chem Biol Interact. 2013 Mar 25; 203(1):212-6. PMID: 22960160; PMCID: PMC3572300.
      Citations: 15     Fields:    Translation:HumansAnimals
    194. Gao Y, Geng L, Orson F, Kinsey B, Kosten TR, Shen X, Brimijoin S. Effects of anti-cocaine vaccine and viral gene transfer of cocaine hydrolase in mice on cocaine toxicity including motor strength and liver damage. Chem Biol Interact. 2013 Mar 25; 203(1):208-11. PMID: 22935511; PMCID: PMC3537841.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    195. Kosten TR, Wu G, Huang W, Harding MJ, Hamon SC, Lappalainen J, Nielsen DA. Pharmacogenetic randomized trial for cocaine abuse: disulfiram and dopamine ?-hydroxylase. Biol Psychiatry. 2013 Feb 01; 73(3):219-24. PMID: 22906516; PMCID: PMC3514624.
      Citations: 44     Fields:    Translation:Humans
    196. Zhang XY, Chen DC, Xiu MH, Hui L, Liu H, Luo X, Zuo L, Zhang H, Kosten TA, Kosten TR. Association of functional dopamine-beta-hydroxylase (DBH) 19 bp insertion/deletion polymorphism with smoking severity in male schizophrenic smokers. Schizophr Res. 2012 Oct; 141(1):48-53. PMID: 22871345.
      Citations: 5     Fields:    Translation:Humans
    197. Han M, Huang XF, Chen DC, Xiu MH, Hui L, Liu H, Kosten TR, Zhang XY. Gender differences in cognitive function of patients with chronic schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2012 Dec 03; 39(2):358-63. PMID: 22820676.
      Citations: 39     Fields:    Translation:Humans
    198. Ramakrishnan M, Alves De Melo F, Kinsey BM, Ladbury JE, Kosten TR, Orson FM. Probing cocaine-antibody interactions in buffer and human serum. PLoS One. 2012; 7(7):e40518. PMID: 22859949; PMCID: PMC3409241.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    199. Zhang X, Guan SL, Wang ZQ, You Y, Sun SL, Hui L, Miao LN, Yu Y, Kosten TR, Zhang XY. No association between the type 2 diabetes mellitus susceptibility gene, SLC30A8 and schizophrenia in a Chinese population. Hum Psychopharmacol. 2012 Jul; 27(4):392-6. PMID: 22778022.
      Citations: 3     Fields:    Translation:Humans
    200. Zhang XY, Chen DC, Xiu MH, Yang FD, Haile CN, Kosten TA, Kosten TR. Gender differences in never-medicated first-episode schizophrenia and medicated chronic schizophrenia patients. J Clin Psychiatry. 2012 Jul; 73(7):1025-33. PMID: 22901352.
      Citations: 29     Fields:    Translation:Humans
    201. Nielsen DA, Utrankar A, Reyes JA, Simons DD, Kosten TR. Epigenetics of drug abuse: predisposition or response. Pharmacogenomics. 2012 Jul; 13(10):1149-60. PMID: 22909205; PMCID: PMC3463407.
      Citations: 37     Fields:    Translation:HumansCells
    202. Sun H, Guo S, Chen D, Yang F, Zou Y, Di X, Cao Y, Kosten T, Lu L, Zhang XY. Association of functional COMT Val108/Met polymorphism with smoking cessation in a nicotine replacement therapy. J Neural Transm (Vienna). 2012 Dec; 119(12):1491-8. PMID: 22695756.
      Citations: 6     Fields:    Translation:Humans
    203. Zhang XY, Zhang WF, Zhou DF, Chen DC, Xiu MH, Wu HR, Haile CN, Kosten TA, Kosten TR. Brain-derived neurotrophic factor levels and its Val66Met gene polymorphism predict tardive dyskinesia treatment response to Ginkgo biloba. Biol Psychiatry. 2012 Oct 15; 72(8):700-6. PMID: 22695185.
      Citations: 11     Fields:    Translation:HumansAnimals
    204. Xiu MH, Chen DC, Wang D, Zhang K, Dong A, Tang W, Zhang F, Liu LJ, Liu JH, Liu HB, Yang FD, Kosten TR, Zhang XY. Elevated interleukin-18 serum levels in chronic schizophrenia: Association with psychopathology. J Psychiatr Res. 2012 Aug; 46(8):1093-8. PMID: 22647522.
      Citations: 12     Fields:    Translation:Humans
    205. Zhang XY, Chen DC, Xiu MH, Haile CN, Sun H, Lu L, Kosten TA, Kosten TR. Cigarette smoking and cognitive function in Chinese male schizophrenia: a case-control study. PLoS One. 2012; 7(5):e36563. PMID: 22570726; PMCID: PMC3343009.
      Citations: 12     Fields:    Translation:Humans
    206. Zhang XY, Chen DC, Xiu MH, Tang W, Zhang F, Liu L, Chen Y, Liu J, Yao JK, Kosten TA, Kosten TR. Plasma total antioxidant status and cognitive impairments in schizophrenia. Schizophr Res. 2012 Aug; 139(1-3):66-72. PMID: 22555016.
      Citations: 21     Fields:    Translation:Humans
    207. Hui L, Zhang X, Huang XF, Han M, Fernandez F, Yu Y, Sun S, Li W, Chen DC, Xiu MH, Kosten TR, Zhang XY. The dopamine b-hydroxylase 19 bp insertion/deletion polymorphism was associated with first-episode but not medicated chronic schizophrenia. J Psychiatr Res. 2012 Jun; 46(6):733-7. PMID: 22445279.
      Citations: 5     Fields:    Translation:Humans
    208. Liu H, Kang Y, Liang J, Li C, Xiu M, Chen D, Yang F, Wang F, Wu G, Haile CN, Kosten TA, Kosten TR, Zhang XY. Lower serum interleukin-2 levels in schizophrenic patients with tardive dyskinesia. Psychiatry Res. 2012 Jul 30; 198(2):329-31. PMID: 22417931.
      Citations: 7     Fields:    Translation:Humans
    209. Sigmon SC, Bisaga A, Nunes EV, O'Connor PG, Kosten T, Woody G. Opioid detoxification and naltrexone induction strategies: recommendations for clinical practice. Am J Drug Alcohol Abuse. 2012 May; 38(3):187-99. PMID: 22404717; PMCID: PMC4331107.
      Citations: 34     Fields:    Translation:Humans
    210. Zhang XY, Chen DC, Xiu MH, Haile CN, Luo X, Xu K, Zhang HP, Zuo L, Zhang Z, Zhang X, Kosten TA, Kosten TR. Cognitive and serum BDNF correlates of BDNF Val66Met gene polymorphism in patients with schizophrenia and normal controls. Hum Genet. 2012 Jul; 131(7):1187-95. PMID: 22362486; PMCID: PMC3671849.
      Citations: 37     Fields:    Translation:Humans
    211. Li WJ, Kou CG, Yu Y, Sun S, Zhang X, Kosten TR, Zhang XY. Association of catechol-O-methyltransferase gene polymorphisms with schizophrenia and negative symptoms in a Chinese population. Am J Med Genet B Neuropsychiatr Genet. 2012 Jun; 159B(4):370-5. PMID: 22354729; PMCID: PMC4190670.
      Citations: 7     Fields:    Translation:Humans
    212. Cui Y, Robinson JD, Versace F, Lam CY, Minnix JA, Karam-Hage M, Dani JA, Kosten TR, Wetter DW, Brown VL, Cinciripini PM. Differential cigarette-related startle cue reactivity among light, moderate, and heavy smokers. Addict Behav. 2012 Aug; 37(8):885-9. PMID: 22571920; PMCID: PMC3358408.
      Citations: 7     Fields:    Translation:Humans
    213. Zhang XY, Liang J, Chen DC, Xiu MH, He J, Cheng W, Wu Z, Yang FD, Haile CN, Sun H, Lu L, Kosten TA, Kosten TR. Cigarette smoking in male patients with chronic schizophrenia in a Chinese population: prevalence and relationship to clinical phenotypes. PLoS One. 2012; 7(2):e30937. PMID: 22347412; PMCID: PMC3274516.
      Citations: 23     Fields:    Translation:Humans
    214. Newton TF, De La Garza R, Brown G, Kosten TR, Mahoney JJ, Haile CN. Noradrenergic a1 receptor antagonist treatment attenuates positive subjective effects of cocaine in humans: a randomized trial. PLoS One. 2012; 7(2):e30854. PMID: 22319592; PMCID: PMC3272014.
      Citations: 27     Fields:    Translation:Humans
    215. Zhang XY, Liang J, Chen DC, Xiu MH, Yang FD, Kosten TA, Kosten TR. Low BDNF is associated with cognitive impairment in chronic patients with schizophrenia. Psychopharmacology (Berl). 2012 Jul; 222(2):277-84. PMID: 22274000.
      Citations: 49     Fields:    Translation:Humans
    216. Zhang XY, Zhou DF, Shen YC, Zhang PY, Zhang WF, Liang J, Chen DC, Xiu MH, Kosten TA, Kosten TR. Effects of risperidone and haloperidol on superoxide dismutase and nitric oxide in schizophrenia. Neuropharmacology. 2012 Apr; 62(5-6):1928-34. PMID: 22227558.
      Citations: 14     Fields:    Translation:Humans
    217. Wang F, Fan H, Sun H, Yang F, Luo Y, Liu H, Kosten TR, Lu L, Zhang XY. Association between TNF-a promoter -308A/G polymorphism and tardive dyskinesian Chinese Han patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2012 Apr 27; 37(1):106-10. PMID: 22227290.
      Citations: 6     Fields:    Translation:HumansCells
    218. Shorter D, Kosten TR. Vaccines in the Treatment of Substance Abuse. Focus (Am Psychiatr Publ). 2011 Dec 01; 2011(9):25-30. PMID: 23472050; PMCID: PMC3587968.
      Citations: 2     
    219. Shen X, Kosten TR. Immunotherapy for drug abuse. CNS Neurol Disord Drug Targets. 2011 Dec; 10(8):876-9. PMID: 22229313; PMCID: PMC3634568.
      Citations: 6     Fields:    Translation:HumansAnimals
    220. Shen XY, Orson FM, Kosten TR. Vaccines against drug abuse. Clin Pharmacol Ther. 2012 Jan; 91(1):60-70. PMID: 22130115; PMCID: PMC3345810.
      Citations: 50     Fields:    Translation:HumansAnimals
    221. Shorter D, Kosten TR. Novel pharmacotherapeutic treatments for cocaine addiction. BMC Med. 2011 Nov 03; 9:119. PMID: 22047090; PMCID: PMC3216852.
      Citations: 39     Fields:    Translation:HumansPHPublic Health
    222. Oliveto A, Poling J, Mancino MJ, Williams DK, Thostenson J, Pruzinsky R, Gonsai K, Sofuoglu M, Gonzalez G, Tripathi S, Kosten TR. Sertraline delays relapse in recently abstinent cocaine-dependent patients with depressive symptoms. Addiction. 2012 Jan; 107(1):131-41. PMID: 21707811; PMCID: PMC3237722.
      Citations: 19     Fields:    Translation:HumansPHPublic Health
    223. Shen X, Orson FM, Kosten TR. Anti-addiction vaccines. F1000 Med Rep. 2011; 3:20. PMID: 22003367; PMCID: PMC3186043.
      Citations: 3     
    224. Anton RF, Litten RZ, Falk DE, Palumbo JM, Bartus RT, Robinson RL, Kranzler HR, Kosten TR, Meyer RE, O'Brien CP, Mann K, Meulien D. The Alcohol Clinical Trials Initiative (ACTIVE): purpose and goals for assessing important and salient issues for medications development in alcohol use disorders. Neuropsychopharmacology. 2012 Jan; 37(2):402-11. PMID: 21900883; PMCID: PMC3242301.
      Citations: 19     Fields:    Translation:Humans
    225. Zhang R, Hao W, Pan M, Wang C, Zhang X, Chen DC, Xiu MH, Yang FD, Kosten TR, Zhang XY. The prevalence and clinical-demographic correlates of diabetes mellitus in chronic schizophrenic patients receiving clozapine. Hum Psychopharmacol. 2011 Aug; 26(6):392-6. PMID: 21826737.
      Citations: 5     Fields:    Translation:Humans
    226. Yang YQ, Sun S, Yu YQ, Li WJ, Zhang X, Xiu MH, Chen DC, De Yang F, Liu H, Li C, Kosten TR, Zhang XY. Decreased serum brain-derived neurotrophic factor levels in schizophrenic patients with tardive dyskinesia. Neurosci Lett. 2011 Sep 08; 502(1):37-40. PMID: 21798311.
      Citations: 9     Fields:    Translation:Humans
    227. Zhang XY, Yu YQ, Sun S, Zhang X, Li W, Xiu MH, Chen DC, Yang FD, Zhu F, Kosten TA, Kosten TR. Smoking and tardive dyskinesia in male patients with chronic schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 15; 35(7):1765-9. PMID: 21723906.
      Citations: 7     Fields:    Translation:HumansAnimals
    228. Kosten TR. Stress and addiction. Am J Psychiatry. 2011 Jun; 168(6):566-8. PMID: 21642477.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    229. Dodrill CL, Helmer DA, Kosten TR. Prescription pain medication dependence. Am J Psychiatry. 2011 May; 168(5):466-71. PMID: 21536702.
      Citations: 14     Fields:    Translation:Humans
    230. Xiang X, Huang W, Haile CN, Kosten TA. Hippocampal GluR1 associates with behavior in the elevated plus maze and shows sex differences. Behav Brain Res. 2011 Sep 23; 222(2):326-31. PMID: 21497621; PMCID: PMC3096704.
      Citations: 14     Fields:    Translation:Animals
    231. Li XF, Zheng YL, Xiu MH, Chen DC, Kosten TR, Zhang XY. Reduced plasma total antioxidant status in first-episode drug-naive patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Jun 01; 35(4):1064-7. PMID: 21392552.
      Citations: 14     Fields:    Translation:Humans
    232. McIntosh BJ, Zhang XY, Kosten T, Tan SP, Xiu MH, Rakofsky J, Harvey PD. Performance-based assessment of functional skills in severe mental illness: results of a large-scale study in China. J Psychiatr Res. 2011 Aug; 45(8):1089-94. PMID: 21300378; PMCID: PMC3112265.
      Citations: 20     Fields:    Translation:Humans
    233. Yang FD, Wang XQ, Liu XP, Zhao KX, Fu WH, Hao XR, Zhang XL, Huang GS, Qu SC, Bai JS, Huang XF, Kosten TR, Zhang XY. Sex difference in QTc prolongation in chronic institutionalized patients with schizophrenia on long-term treatment with typical and atypical antipsychotics. Psychopharmacology (Berl). 2011 Jul; 216(1):9-16. PMID: 21301815.
      Citations: 17     Fields:    Translation:Humans
    234. Cao JX, Hu J, Ye XM, Xia Y, Haile CA, Kosten TR, Zhang XY. Association between the 5-HTR1B gene polymorphisms and alcohol dependence in a Han Chinese population. Brain Res. 2011 Feb 28; 1376:1-9. PMID: 21172311.
      Citations: 11     Fields:    Translation:Humans
    235. Kinsey BM, Kosten TR, Orson FM. Anti-cocaine vaccine development. Expert Rev Vaccines. 2010 Sep; 9(9):1109-14. PMID: 20822352; PMCID: PMC2936703.
      Citations: 20     Fields:    Translation:Humans
    236. Li SX, Liu LJ, Jiang WG, Sun LL, Zhou SJ, Le Foll B, Zhang XY, Kosten TR, Lu L. Circadian alteration in neurobiology during protracted opiate withdrawal in rats. J Neurochem. 2010 Oct; 115(2):353-62. PMID: 20738730.
      Citations: 15     Fields:    Translation:Animals
    237. Chen DC, Zhou MA, Zhou DH, Xiu MH, Wu GY, Kosten TR, Zhang XY. Gender differences in the prevalence of diabetes mellitus in chronic hospitalized patients with schizophrenia on long-term antipsychotics. Psychiatry Res. 2011 Apr 30; 186(2-3):451-3. PMID: 20797801.
      Citations: 4     Fields:    Translation:Humans
    238. Oliveto A, Gentry WB, Pruzinsky R, Gonsai K, Kosten TR, Martell B, Poling J. Behavioral effects of gamma-hydroxybutyrate in humans. Behav Pharmacol. 2010 Jul; 21(4):332-42. PMID: 20526195; PMCID: PMC2911496.
      Citations: 5     Fields:    Translation:Humans
    239. Zhang XY, Li CB, Li M, Zheng YL, Zhang CX, Yan QZ, Liu WZ, Kang YM, Wang F, Chen DC, Xiu MH, Kosten TR. Smoking initiation and schizophrenia: a replication study in a Chinese Han population. Schizophr Res. 2010 Jun; 119(1-3):110-4. PMID: 20022218.
      Citations: 7     Fields:    Translation:Humans
    240. Najavits LM, Norman SB, Kivlahan D, Kosten TR. Improving PTSD/substance abuse treatment in the VA: a survey of providers. Am J Addict. 2010 May-Jun; 19(3):257-63. PMID: 20525033.
      Citations: 11     Fields:    Translation:Humans
    241. Zhou DH, Yan QZ, Yan XM, Li CB, Fang H, Zheng YL, Zhang CX, Yao HJ, Chen DC, Xiu MH, Kosten TR, Zhang XY. The study of BDNF Val66Met polymorphism in Chinese schizophrenic patients. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Aug 16; 34(6):930-3. PMID: 20420877.
      Citations: 10     Fields:    Translation:Humans
    242. Chen DC, Xiu MH, Liu H, Zhang BS, Wang Y, Kosten TR, Zhang XY. Reduced status of plasma total antioxidant capacity in schizophrenia with tardive dyskinesia. J Psychiatr Res. 2010 Nov; 44(15):1111-2. PMID: 20398909.
      Citations: 2     Fields:    Translation:Humans
    243. Wang Y, Wang JD, Wu HR, Zhang BS, Fang H, Ma QM, Liu H, Chen DC, Xiu MH, Hail CN, Kosten TR, Zhang XY. The Val66Met polymorphism of the brain-derived neurotrophic factor gene is not associated with risk for schizophrenia and tardive dyskinesia in Han Chinese population. Schizophr Res. 2010 Jul; 120(1-3):240-2. PMID: 20395113.
      Citations: 5     Fields:    Translation:Humans
    244. Kinsey BM, Kosten TR, Orson FM. Active immunotherapy for the Treatment of Cocaine Dependence. Drugs Future. 2010 Apr 01; 35(4):301-306. PMID: 21796226; PMCID: PMC3142961.
      Citations: 3     
    245. Liu H, Wang C, Chen PH, Zhang BS, Zheng YL, Zhang CX, Meng HQ, Wang Y, Chen DC, Xiu MH, Kosten TR, Zhang XY. Association of the manganese superoxide dismutase gene Ala-9Val polymorphism with clinical phenotypes and tardive dyskinesia in schizophrenic patients. Prog Neuropsychopharmacol Biol Psychiatry. 2010 May 30; 34(4):692-6. PMID: 20346996.
      Citations: 7     Fields:    Translation:Humans
    246. Zhang XY, Zhang RL, Pan M, Chen DC, Xiu MH, Kosten TR. Sex difference in the prevalence of smoking in Chinese schizophrenia. J Psychiatr Res. 2010 Oct; 44(14):986-8. PMID: 20334878.
      Citations: 10     Fields:    Translation:Humans
    247. Haile CN, Kosten TR. The potential of pharmacogenomics to treat drug addiction. Pharmacogenomics. 2009 Dec; 10(12):1883-6. PMID: 19958085.
      Citations: 4     Fields:    Translation:Humans
    248. Zhang XY, Xiu MH, Chen DC, Zhu FY, Wu GY, Haile CN, Lu L, Kosten TA, Kosten TR. Increased S100B serum levels in schizophrenic patients with tardive dyskinesia: association with dyskinetic movements. J Psychiatr Res. 2010 May; 44(7):429-33. PMID: 19932492.
      Citations: 6     Fields:    Translation:Humans
    249. Zhao LY, Shi J, Zhang XL, Epstein DH, Zhang XY, Liu Y, Kosten TR, Lu L. Stress enhances retrieval of drug-related memories in abstinent heroin addicts. Neuropsychopharmacology. 2010 Feb; 35(3):720-6. PMID: 19890257; PMCID: PMC3055613.
      Citations: 8     Fields:    Translation:Humans
    250. Stitzer ML, Polk T, Bowles S, Kosten T. Drug users' adherence to a 6-month vaccination protocol: effects of motivational incentives. Drug Alcohol Depend. 2010 Feb 01; 107(1):76-9. PMID: 19828264; PMCID: PMC2815120.
      Citations: 25     Fields:    Translation:HumansPHPublic Health
    251. Martell BA, Orson FM, Poling J, Mitchell E, Rossen RD, Gardner T, Kosten TR. Cocaine vaccine for the treatment of cocaine dependence in methadone-maintained patients: a randomized, double-blind, placebo-controlled efficacy trial. Arch Gen Psychiatry. 2009 Oct; 66(10):1116-23. PMID: 19805702; PMCID: PMC2878137.
      Citations: 124     Fields:    Translation:HumansPHPublic Health
    252. Chen DC, Wang J, Wang B, Yang SC, Zhang CX, Zheng YL, Li YL, Wang N, Yang KB, Xiu MH, Kosten TR, Zhang XY. Decreased levels of serum brain-derived neurotrophic factor in drug-na?ve first-episode schizophrenia: relationship to clinical phenotypes. Psychopharmacology (Berl). 2009 Dec; 207(3):375-80. PMID: 19787338.
      Citations: 49     Fields:    Translation:Humans
    253. Xiu MH, Hui L, Dang YF, Hou TD, Zhang CX, Zheng YL, Chen DC, Kosten TR, Zhang XY. Decreased serum BDNF levels in chronic institutionalized schizophrenia on long-term treatment with typical and atypical antipsychotics. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Nov 13; 33(8):1508-12. PMID: 19720106.
      Citations: 51     Fields:    Translation:Humans
    254. Stotts AL, Dodrill CL, Kosten TR. Opioid dependence treatment: options in pharmacotherapy. Expert Opin Pharmacother. 2009 Aug; 10(11):1727-40. PMID: 19538000; PMCID: PMC2874458.
      Citations: 91     Fields:    Translation:Humans
    255. Chen JX, Su YA, Wang SL, Bian QT, Liu YH, Wang N, Yang FD, Haile C, Kosten TR, Zhang XY. Aripiprazole treatment of risperidone-induced hyperprolactinemia. J Clin Psychiatry. 2009 Jul; 70(7):1058-9. PMID: 19653986.
      Citations: 5     Fields:    Translation:Humans
    256. Qiu HT, Meng HQ, Song C, Xiu MH, Chen DC, Zhu FY, Wu GY, Kosten TA, Kosten TR, Zhang XY. Association between monoamine oxidase (MAO)-A gene variants and schizophrenia in a Chinese population. Brain Res. 2009 Sep 01; 1287:67-73. PMID: 19573521.
      Citations: 11     Fields:    Translation:Humans
    257. Zhang XY, Chen DC, Xiu MH, Wang F, Qi LY, Sun HQ, Chen S, He SC, Wu GY, Haile CN, Kosten TA, Lu L, Kosten TR. The novel oxidative stress marker thioredoxin is increased in first-episode schizophrenic patients. Schizophr Res. 2009 Sep; 113(2-3):151-7. PMID: 19540723.
      Citations: 23     Fields:    Translation:Humans
    258. Qi LY, Xiu MH, Chen DC, Wang F, Kosten TA, Kosten TR, Zhang XY. Increased serum S100B levels in chronic schizophrenic patients on long-term clozapine or typical antipsychotics. Neurosci Lett. 2009 Sep 22; 462(2):113-7. PMID: 19539717.
      Citations: 8     Fields:    Translation:Humans
    259. Zhang XY, Chen DC, Qi LY, Wang F, Xiu MH, Chen S, Wu GY, Kosten TA, Kosten TR. Gender differences in the prevalence, risk and clinical correlates of tardive dyskinesia in Chinese schizophrenia. Psychopharmacology (Berl). 2009 Sep; 205(4):647-54. PMID: 19529921.
      Citations: 5     Fields:    Translation:Humans
    260. Shi J, Jun W, Zhao LY, Xue YX, Zhang XY, Kosten TR, Lu L. Effect of rapamycin on cue-induced drug craving in abstinent heroin addicts. Eur J Pharmacol. 2009 Aug 01; 615(1-3):108-12. PMID: 19470385.
      Citations: 14     Fields:    Translation:Humans
    261. Orson FM, Kinsey BM, Singh RA, Wu Y, Kosten TR. Vaccines for cocaine abuse. Hum Vaccin. 2009 Apr; 5(4):194-9. PMID: 19276665; PMCID: PMC2878138.
      Citations: 24     Fields:    Translation:Humans
    262. Zhang XY, Zhou DF, Qi LY, Chen S, Cao LY, Chen DC, Xiu MH, Wang F, Wu GY, Lu L, Kosten TA, Kosten TR. Superoxide dismutase and cytokines in chronic patients with schizophrenia: association with psychopathology and response to antipsychotics. Psychopharmacology (Berl). 2009 May; 204(1):177-84. PMID: 19139851.
      Citations: 15     Fields:    Translation:Humans
    263. Li SX, Shi J, Epstein DH, Wang X, Zhang XL, Bao YP, Zhang D, Zhang XY, Kosten TR, Lu L. Circadian alteration in neurobiology during 30 days of abstinence in heroin users. Biol Psychiatry. 2009 May 15; 65(10):905-12. PMID: 19135652.
      Citations: 18     Fields:    Translation:HumansAnimals
    264. Shi J, Li SX, Zhang XL, Wang X, Le Foll B, Zhang XY, Kosten TR, Lu L. Time-dependent neuroendocrine alterations and drug craving during the first month of abstinence in heroin addicts. Am J Drug Alcohol Abuse. 2009; 35(5):267-72. PMID: 19591065.
      Citations: 20     Fields:    Translation:Humans
    265. Sofuoglu M, Poling J, Hill K, Kosten T. Atomoxetine attenuates dextroamphetamine effects in humans. Am J Drug Alcohol Abuse. 2009; 35(6):412-6. PMID: 20014909; PMCID: PMC2796580.
      Citations: 18     Fields:    Translation:Humans
    266. Lu L, Wang X, Kosten TR. Stereotactic neurosurgical treatment of drug addiction. Am J Drug Alcohol Abuse. 2009; 35(6):391-3. PMID: 20014906.
      Citations: 4     Fields:    Translation:Humans
    267. Lu L, Liu Y, Zhu W, Shi J, Liu Y, Ling W, Kosten TR. Traditional medicine in the treatment of drug addiction. Am J Drug Alcohol Abuse. 2009; 35(1):1-11. PMID: 19152199.
      Citations: 36     Fields:    Translation:HumansAnimals
    268. Sun HQ, Guo S, Chen DF, Jiang ZN, Liu Y, Di XL, Yang FD, Zhang XY, Kosten TR, Lu L. Family support and employment as predictors of smoking cessation success: a randomized, double-blind, placebo-controlled trial of nicotine sublingual tablets in chinese smokers. Am J Drug Alcohol Abuse. 2009; 35(3):183-8. PMID: 19462302.
      Citations: 15     Fields:    Translation:Humans
    269. Kosten TR, Vidal X, Colom J, Casas M, Castells X, Capell? D. Efficacy of opiate maintenance therapy and adjunctive interventions for opioid dependence with comorbid cocaine use disorders: A systematic review and meta-analysis of controlled clinical trials. Am J Drug Alcohol Abuse. 2009; 35(5):339-49. PMID: 20180662.
      Citations: 24     Fields:    Translation:Humans
    270. Haile CN, Kosten TR, Kosten TA. Pharmacogenetic treatments for drug addiction: cocaine, amphetamine and methamphetamine. Am J Drug Alcohol Abuse. 2009; 35(3):161-77. PMID: 19462300; PMCID: PMC2754046.
      Citations: 30     Fields:    Translation:Humans
    271. Xiu MH, Chen S, Wang F, Cao LY, Qi LY, Chen DC, Wu GY, Lu L, Kosten TA, Kosten TR, Zhang XY. Altered interleukin-3 serum levels in drug-na?ve and neuroleptic-treated schizophrenic patients. Schizophr Res. 2008 Dec; 106(2-3):369-70. PMID: 18838250.
      Citations: 2     Fields:    Translation:Humans
    272. Chen DC, Qi LY, Xiu MH, Cao LY, Wang F, Chen S, Wu GY, Kosten TA, Kosten TR, Zhang XY. Elevated serum levels of tumor necrosis factor-alpha in clozapine-associated obesity in chronic schizophrenia. Schizophr Res. 2008 Dec; 106(2-3):367-8. PMID: 18835132.
      Citations: 3     Fields:    Translation:Humans
    273. Orson FM, Kinsey BM, Singh RA, Wu Y, Gardner T, Kosten TR. Substance abuse vaccines. Ann N Y Acad Sci. 2008 Oct; 1141:257-69. PMID: 18991962; PMCID: PMC2587140.
      Citations: 40     Fields:    Translation:HumansAnimals
    274. Ren ZY, Zhang XL, Liu Y, Zhao LY, Shi J, Bao Y, Zhang XY, Kosten TR, Lu L. Diurnal variation in cue-induced responses among protracted abstinent heroin users. Pharmacol Biochem Behav. 2009 Jan; 91(3):468-72. PMID: 18809427.
      Citations: 8     Fields:    Translation:Humans
    275. Zhang XY, Cao LY, Song C, Wu GY, Chen DC, Qi LY, Wang F, Xiu MH, Chen S, Zhang Y, Lu L, Kosten TA, Kosten TR. Lower serum cytokine levels in smokers than nonsmokers with chronic schizophrenia on long-term treatment with antipsychotics. Psychopharmacology (Berl). 2008 Dec; 201(3):383-9. PMID: 18719893.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    276. Mooney ME, Poling J, Gonzalez G, Gonsai K, Kosten T, Sofuoglu M. Preliminary study of buprenorphine and bupropion for opioid-dependent smokers. Am J Addict. 2008 Jul-Aug; 17(4):287-92. PMID: 18612883; PMCID: PMC2588345.
      Citations: 23     Fields:    Translation:Humans
    277. Sun S, Wang F, Wei J, Cao LY, Qi LY, Xiu MH, Chen S, Li XH, Kosten TA, Kosten TR, Zhang XY. Association between interleukin-6 receptor polymorphism and patients with schizophrenia. Schizophr Res. 2008 Jul; 102(1-3):346-7. PMID: 18508242.
      Citations: 8     Fields:    Translation:Humans
    278. Sun S, Wang F, Wei J, Cao LY, Wu GY, Lu L, Kosten TA, Kosten TR, Zhang XY. Association between interleukin-3 receptor alpha polymorphism and schizophrenia in the Chinese population. Neurosci Lett. 2008 Jul 25; 440(1):35-7. PMID: 18547720.
      Citations: 10     Fields:    Translation:Humans
    279. Wang F, Xiu MH, Zhou DF, Cao LY, Wu GY, Kosten TA, Kosten TR, Zhang XY. The CCR5 32-bp deletion allele is rare in a Chinese population. Schizophr Res. 2008 Apr; 101(1-3):341-3. PMID: 18295459.
      Citations: 1     Fields:    Translation:Humans
    280. Haile CN, Kosten TA, Kosten TR. Pharmacogenetic treatments for drug addiction: alcohol and opiates. Am J Drug Alcohol Abuse. 2008; 34(4):355-81. PMID: 18584566.
      Citations: 22     Fields:    Translation:Humans
    281. Kosten TA, Zhang XY. Sex differences in non-reinforced responding for cocaine. Am J Drug Alcohol Abuse. 2008; 34(4):473-88. PMID: 18584577.
      Citations: 13     Fields:    Translation:Animals
    282. Kosten TR, Gardner TJ. New hot topics sections: 1. China's new march forward in addiction treatment: methadone for the masses. 2. Issues in formulating DSM V. Am J Drug Alcohol Abuse. 2008; 34(2):123-6. PMID: 18293228.
      Citations: 1     Fields:    Translation:Humans
    283. Li SX, Li J, Epstein DH, Zhang XY, Kosten TR, Lu L. Serum cortisol secretion during heroin abstinence is elevated only nocturnally. Am J Drug Alcohol Abuse. 2008; 34(3):321-8. PMID: 18428074; PMCID: PMC3686295.
      Citations: 11     Fields:    Translation:Humans
    284. Zhang XY, Zhou DF, Wu GY, Cao LY, Tan YL, Haile CN, Li J, Lu L, Kosten TA, Kosten TR. BDNF levels and genotype are associated with antipsychotic-induced weight gain in patients with chronic schizophrenia. Neuropsychopharmacology. 2008 Aug; 33(9):2200-5. PMID: 17987059.
      Citations: 33     Fields:    Translation:Humans
    285. Sofuoglu M, Poling J, Gonzalez G, Gonsai K, Oliveto A, Kosten TR. Progesterone effects on cocaine use in male cocaine users maintained on methadone: a randomized, double-blind, pilot study. Exp Clin Psychopharmacol. 2007 Oct; 15(5):453-60. PMID: 17924779.
      Citations: 20     Fields:    Translation:Humans
    286. Orson FM, Kinsey BM, Singh RA, Wu Y, Gardner T, Kosten TR. The future of vaccines in the management of addictive disorders. Curr Psychiatry Rep. 2007 Oct; 9(5):381-7. PMID: 17915077.
      Citations: 15     Fields:    Translation:Humans
    287. Wang ZR, Zhou DF, Cao LY, Tan YL, Zhang XY, Li J, Lu L, Wu GY, Kosten TA, Kosten TR. Brain-derived neurotrophic factor polymorphisms and smoking in schizophrenia. Schizophr Res. 2007 Dec; 97(1-3):299-301. PMID: 17869486.
      Citations: 2     Fields:    Translation:HumansCells
    288. Li W, Wei J, Zhou DF, Tan YL, Cao YL, Zhang XY, Wu G, Kosten TA, Kosten TR. Lack of association between the BDNF C270T polymorphism and schizophrenia in a Chinese Han population. Schizophr Res. 2007 Dec; 97(1-3):297-8. PMID: 17669628.
      Citations: 2     Fields:    Translation:Humans
    289. Zhang XY, Tan YL, Zhou DF, Haile CN, Cao LY, Xu Q, Shen Y, Kosten TA, Kosten TR. Association of clozapine-induced weight gain with a polymorphism in the leptin promoter region in patients with chronic schizophrenia in a Chinese population. J Clin Psychopharmacol. 2007 Jun; 27(3):246-51. PMID: 17502770.
      Citations: 17     Fields:    Translation:HumansCellsCTClinical Trials
    290. Poling J, Pruzinsky R, Kosten TR, Gonsai K, Sofuoglu M, Gonzalez G, Oliveto A. Clinical efficacy of citalopram alone or augmented with bupropion in methadone-stabilized patients. Am J Addict. 2007 May-Jun; 16(3):187-94. PMID: 17612822.
      Citations: 3     Fields:    Translation:Humans
    291. Zhang XY, Tan YL, Zhou DF, Cao LY, Wu GY, Haile CN, Kosten TA, Kosten TR. Disrupted antioxidant enzyme activity and elevated lipid peroxidation products in schizophrenic patients with tardive dyskinesia. J Clin Psychiatry. 2007 May; 68(5):754-60. PMID: 17503985.
      Citations: 18     Fields:    Translation:HumansCells
    292. Kleber HD, Weiss RD, Anton RF, George TP, Greenfield SF, Kosten TR, O'Brien CP, Rounsaville BJ, Strain EC, Ziedonis DM, Hennessy G, Connery HS, McIntyre JS, Charles SC, Anzia DJ, Cook IA, Finnerty MT, Johnson BR, Nininger JE, Summergrad P, Woods SM, Yager J, Pyles R, Cross CD, Peele R, Shemo JP, Lurie L, Walker RD, Barnovitz MA, Gray SH, Saxena S, Tonnu T, Kunkle R, Albert AB, Fochtmann LJ, Hart C, Regier D, Work Group on Substance Use Disorders, American Psychiatric Association, Steering Committee on Practice Guidelines. Treatment of patients with substance use disorders, second edition. American Psychiatric Association. Am J Psychiatry. 2007 Apr; 164(4 Suppl):5-123. PMID: 17569411.
      Citations: 41     Fields:    Translation:Humans
    293. Zhang XY, Tan YL, Zhou DF, Haile CN, Wu GY, Cao LY, Kosten TA, Kosten TR. Nicotine dependence, symptoms and oxidative stress in male patients with schizophrenia. Neuropsychopharmacology. 2007 Sep; 32(9):2020-4. PMID: 17228336.
      Citations: 14     Fields:    Translation:Humans
    294. Martell BA, O'Connor PG, Kerns RD, Becker WC, Morales KH, Kosten TR, Fiellin DA. Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction. Ann Intern Med. 2007 Jan 16; 146(2):116-27. PMID: 17227935.
      Citations: 213     Fields:    Translation:Humans
    295. Guo S, Chen DF, Zhou DF, Sun HQ, Wu GY, Haile CN, Kosten TA, Kosten TR, Zhang XY. Association of functional catechol O-methyl transferase (COMT) Val108Met polymorphism with smoking severity and age of smoking initiation in Chinese male smokers. Psychopharmacology (Berl). 2007 Mar; 190(4):449-56. PMID: 17206495.
      Citations: 20     Fields:    Translation:Humans
    296. Gardner TJ, Kosten TR. Pharmacotherapeutic environments for substance use disorders. Am J Drug Alcohol Abuse. 2007; 33(5):627-9. PMID: 17891655.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    297. Lane SD, Moeller FG, Steinberg JL, Buzby M, Kosten TR. Performance of cocaine dependent individuals and controls on a response inhibition task with varying levels of difficulty. Am J Drug Alcohol Abuse. 2007; 33(5):717-26. PMID: 17891664.
      Citations: 41     Fields:    Translation:Humans
    298. Poling J, Kosten TR, Sofuoglu M. Treatment outcome predictors for cocaine dependence. Am J Drug Alcohol Abuse. 2007; 33(2):191-206. PMID: 17497542.
      Citations: 60     Fields:    Translation:Humans
    299. Kosten TR. Pharmacotherapy for addictions: partnering with contingency management. Am J Drug Alcohol Abuse. 2007; 33(3):341-2. PMID: 17613962.
      Citations: 1     Fields:    Translation:Humans
    300. Brown AE, Pavlik VN, Shegog R, Whitney SN, Friedman LC, Romero C, Davis GC, Cech I, Kosten TR, Volk RJ. Association of spirituality and sobriety during a behavioral spirituality intervention for Twelve Step (TS) recovery. Am J Drug Alcohol Abuse. 2007; 33(4):611-7. PMID: 17668347.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    301. Gardner TJ, Kosten TR. Human laboratory and neuroimaging studies in substance use disorders: developing new treatment approaches. Am J Drug Alcohol Abuse. 2007; 33(6):765-7. PMID: 17994472.
      Citations:    Fields:    Translation:Humans
    302. Gardner TJ, Kosten TR. Therapeutic options and challenges for substances of abuse. Dialogues Clin Neurosci. 2007; 9(4):431-45. PMID: 18286802; PMCID: PMC3202509.
      Citations: 3     Fields:    Translation:HumansAnimals
    303. Sinha R, Kimmerling A, Doebrick C, Kosten TR. Effects of lofexidine on stress-induced and cue-induced opioid craving and opioid abstinence rates: preliminary findings. Psychopharmacology (Berl). 2007 Mar; 190(4):569-74. PMID: 17136399.
      Citations: 71     Fields:    Translation:HumansPHPublic Health
    304. Zhang XY, Tan YL, Zhou DF, Cao LY, Wu GY, Xu Q, Shen Y, Haile CN, Kosten TA, Kosten TR. Serum BDNF levels and weight gain in schizophrenic patients on long-term treatment with antipsychotics. J Psychiatr Res. 2007 Dec; 41(12):997-1004. PMID: 17095017.
      Citations: 28     Fields:    Translation:Humans
    305. Haile CN, Kosten TR, Kosten TA. Genetics of dopamine and its contribution to cocaine addiction. Behav Genet. 2007 Jan; 37(1):119-45. PMID: 17063402.
      Citations: 17     Fields:    Translation:HumansAnimals
    306. Desai R, Sofuoglu M, Poling J, Oliveto A, Gonsai K, Kosten TR, Gonz?lez G. Clinical efficacy of gabapentin versus tiagabine for reducing cocaine use among cocaine dependent methadone-treated patients. Drug Alcohol Depend. 2007 Feb 23; 87(1):1-9. PMID: 16930857.
      Citations: 31     Fields:    Translation:Humans
    307. Sofuoglu M, Kosten TR. Emerging pharmacological strategies in the fight against cocaine addiction. Expert Opin Emerg Drugs. 2006 Mar; 11(1):91-8. PMID: 16503828.
      Citations: 42     Fields:    Translation:HumansAnimals
    308. Kosten TR, Scanley BE, Tucker KA, Oliveto A, Prince C, Sinha R, Potenza MN, Skudlarski P, Wexler BE. Cue-induced brain activity changes and relapse in cocaine-dependent patients. Neuropsychopharmacology. 2006 Mar; 31(3):644-50. PMID: 16123763.
      Citations: 147     Fields:    Translation:Humans
    309. Li CS, Kosten TR, Sinha R. Antisocial personality and stress-induced brain activation in cocaine-dependent patients. Neuroreport. 2006 Feb 27; 17(3):243-7. PMID: 16462591.
      Citations: 6     Fields:    Translation:Humans
    310. Poling J, Oliveto A, Petry N, Sofuoglu M, Gonsai K, Gonzalez G, Martell B, Kosten TR. Six-month trial of bupropion with contingency management for cocaine dependence in a methadone-maintained population. Arch Gen Psychiatry. 2006 Feb; 63(2):219-28. PMID: 16461866.
      Citations: 81     Fields:    Translation:HumansPHPublic Health
    311. Sofuoglu M, Poling J, Mouratidis M, Kosten T. Effects of topiramate in combination with intravenous nicotine in overnight abstinent smokers. Psychopharmacology (Berl). 2006 Mar; 184(3-4):645-51. PMID: 16432681.
      Citations: 24     Fields:    Translation:Humans
    312. Sofuoglu M, Poling J, Gonzalez G, Gonsai K, Kosten T. Cocaine withdrawal symptoms predict medication response in cocaine users. Am J Drug Alcohol Abuse. 2006; 32(4):617-27. PMID: 17127550.
      Citations: 6     Fields:    Translation:Humans
    313. Sofuoglu M, Poling J, Mitchell E, Kosten TR. Tiagabine affects the subjective responses to cocaine in humans. Pharmacol Biochem Behav. 2005 Nov; 82(3):569-73. PMID: 16332385.
      Citations: 10     Fields:    Translation:Humans
    314. Sinha R, Lacadie C, Skudlarski P, Fulbright RK, Rounsaville BJ, Kosten TR, Wexler BE. Neural activity associated with stress-induced cocaine craving: a functional magnetic resonance imaging study. Psychopharmacology (Berl). 2005 Dec; 183(2):171-80. PMID: 16163517.
      Citations: 101     Fields:    Translation:Humans
    315. Sofuoglu M, Mouratidis M, Yoo S, Culligan K, Kosten T. Effects of tiagabine in combination with intravenous nicotine in overnight abstinent smokers. Psychopharmacology (Berl). 2005 Sep; 181(3):504-10. PMID: 15983800.
      Citations: 24     Fields:    Translation:Humans
    316. Kosten T, Owens SM. Immunotherapy for the treatment of drug abuse. Pharmacol Ther. 2005 Oct; 108(1):76-85. PMID: 16023218.
      Citations: 54     Fields:    Translation:HumansAnimals
    317. Oliveto A, Poling J, Sevarino KA, Gonsai KR, McCance-Katz EF, Stine SM, Kosten TR. Efficacy of dose and contingency management procedures in LAAM-maintained cocaine-dependent patients. Drug Alcohol Depend. 2005 Aug 01; 79(2):157-65. PMID: 16002025.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    318. Martell BA, Mitchell E, Poling J, Gonsai K, Kosten TR. Vaccine pharmacotherapy for the treatment of cocaine dependence. Biol Psychiatry. 2005 Jul 15; 58(2):158-64. PMID: 16038686.
      Citations: 93     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    319. Kosten TR. What are America's opportunities for harm reduction strategies in opiate dependence? Am J Addict. 2005 Jul-Sep; 14(4):307-10. PMID: 16188710.
      Citations:    Fields:    Translation:Humans
    320. Boutros NN, Lisanby SH, McClain-Furmanski D, Oliwa G, Gooding D, Kosten TR. Cortical excitability in cocaine-dependent patients: a replication and extension of TMS findings. J Psychiatr Res. 2005 May; 39(3):295-302. PMID: 15725428.
      Citations: 9     Fields:    Translation:Humans
    321. Abi-Saab D, Beauvais J, Mehm J, Brody M, Gottschalk C, Kosten TR. The effect of alcohol on the neuropsychological functioning of recently abstinent cocaine-dependent subjects. Am J Addict. 2005 Mar-Apr; 14(2):166-78. PMID: 16019965.
      Citations: 3     Fields:    Translation:Humans
    322. Li CS, Kosten TR, Sinha R. Sex differences in brain activation during stress imagery in abstinent cocaine users: a functional magnetic resonance imaging study. Biol Psychiatry. 2005 Mar 01; 57(5):487-94. PMID: 15737663.
      Citations: 56     Fields:    Translation:Humans
    323. Schottenfeld RS, Chawarski MC, Pakes JR, Pantalon MV, Carroll KM, Kosten TR. Methadone versus buprenorphine with contingency management or performance feedback for cocaine and opioid dependence. Am J Psychiatry. 2005 Feb; 162(2):340-9. PMID: 15677600.
      Citations: 43     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    324. Kosten T, Sofuoglu M, Poling J, Gonsai K, Oliveto A. Desipramine treatment for cocaine dependence in buprenorphine- or methadone-treated patients: baseline urine results as predictor of response. Am J Addict. 2005 Jan-Feb; 14(1):8-17. PMID: 15804873.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    325. Sofuoglu M, Kosten TR. Novel approaches to the treatment of cocaine addiction. CNS Drugs. 2005; 19(1):13-25. PMID: 15651902.
      Citations: 34     Fields:    Translation:HumansAnimals
    326. Kosten TR. Future of anti-addiction vaccines. Stud Health Technol Inform. 2005; 118:177-85. PMID: 16301778.
      Citations: 1     Fields:    Translation:Humans
    327. Sofuoglu M, Kosten TR. Pharmacologic management of relapse prevention in addictive disorders. Psychiatr Clin North Am. 2004 Dec; 27(4):627-48. PMID: 15550284.
      Citations: 9     Fields:    Translation:Humans
    328. O'Brien CP, Charney DS, Lewis L, Cornish JW, Post RM, Woody GE, Zubieta JK, Anthony JC, Blaine JD, Bowden CL, Calabrese JR, Carroll K, Kosten T, Rounsaville B, Childress AR, Oslin DW, Pettinati HM, Davis MA, Demartino R, Drake RE, Fleming MF, Fricks L, Glassman AH, Levin FR, Nunes EV, Johnson RL, Jordan C, Kessler RC, Laden SK, Regier DA, Renner JA, Ries RK, Sklar-Blake T, Weisner C. Priority actions to improve the care of persons with co-occurring substance abuse and other mental disorders: a call to action. Biol Psychiatry. 2004 Nov 15; 56(10):703-13. PMID: 15556110.
      Citations: 55     Fields:    Translation:Humans
    329. Kosten TR, Kosten TA. New medication strategies for comorbid substance use and bipolar affective disorders. Biol Psychiatry. 2004 Nov 15; 56(10):771-7. PMID: 15556122.
      Citations: 2     Fields:    Translation:Humans
    330. Fiellin DA, Kleber H, Trumble-Hejduk JG, McLellan AT, Kosten TR. Consensus statement on office-based treatment of opioid dependence using buprenorphine. J Subst Abuse Treat. 2004 Sep; 27(2):153-9. PMID: 15450648.
      Citations: 42     Fields:    Translation:Humans
    331. Carroll KM, Kosten TR, Rounsaville BJ. Choosing a behavioral therapy platform for pharmacotherapy of substance users. Drug Alcohol Depend. 2004 Aug 16; 75(2):123-34. PMID: 15276217; PMCID: PMC3668430.
      Citations: 36     Fields:    Translation:Humans
    332. Sofuoglu M, Mitchell E, Kosten TR. Effects of progesterone treatment on cocaine responses in male and female cocaine users. Pharmacol Biochem Behav. 2004 Aug; 78(4):699-705. PMID: 15301924.
      Citations: 63     Fields:    Translation:HumansCTClinical Trials
    333. Oliveto A, Poling J, Kosten TR, Gonsai K. Isradipine and dextromethorphan in methadone-maintained humans under a naloxone discrimination procedure. Eur J Pharmacol. 2004 May 03; 491(2-3):157-68. PMID: 15140632.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    334. Tucker KA, Browndyke JN, Gottschalk PC, Cofrancesco AT, Kosten TR. Gender-specific vulnerability for rCBF abnormalities among cocaine abusers. Neuroreport. 2004 Apr 09; 15(5):797-801. PMID: 15073517.
      Citations: 8     Fields:    Translation:Humans
    335. Gonzalez G, Oliveto A, Kosten TR. Combating opiate dependence: a comparison among the available pharmacological options. Expert Opin Pharmacother. 2004 Apr; 5(4):713-25. PMID: 15102558.
      Citations: 31     Fields:    Translation:Humans
    336. Haney M, Kosten TR. Therapeutic vaccines for substance dependence. Expert Rev Vaccines. 2004 Feb; 3(1):11-8. PMID: 14761239.
      Citations: 24     Fields:    Translation:HumansAnimals
    337. West JC, Kosten TR, Wilk J, Svikis D, Triffleman E, Rae DS, Narrow WE, Duffy FF, Regier DA. Challenges in increasing access to buprenorphine treatment for opiate addiction. Am J Addict. 2004; 13 Suppl 1:S8-16. PMID: 15204672.
      Citations: 18     Fields:    Translation:Humans
    338. Kosten TR, Fiellin DA, U.S. National Buprenorphine Implementation Program. Buprenorphine for office-based practice: consensus conference overview. Am J Addict. 2004; 13 Suppl 1:S1-7. PMID: 15204671.
      Citations: 4     Fields:    Translation:Humans
    339. Kosten TR, Tucker K, Gottschalk PC, Rinder CS, Rinder HM. Platelet abnormalities associated with cerebral perfusion defects in cocaine dependence. Biol Psychiatry. 2004 Jan 01; 55(1):91-7. PMID: 14706430.
      Citations: 4     Fields:    Translation:HumansCells
    340. Gonzalez G, Sevarino K, Sofuoglu M, Poling J, Oliveto A, Gonsai K, George TP, Kosten TR. Tiagabine increases cocaine-free urines in cocaine-dependent methadone-treated patients: results of a randomized pilot study. Addiction. 2003 Nov; 98(11):1625-32. PMID: 14616189.
      Citations: 37     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    341. Haile CN, During MJ, Jatlow PI, Kosten TR, Kosten TA. Disulfiram facilitates the development and expression of locomotor sensitization to cocaine in rats. Biol Psychiatry. 2003 Nov 01; 54(9):915-21. PMID: 14573319.
      Citations: 20     Fields:    Translation:Animals
    342. Kosten TR, Gottschalk PC, Tucker K, Rinder CS, Dey HM, Rinder HM. Aspirin or amiloride for cerebral perfusion defects in cocaine dependence. Drug Alcohol Depend. 2003 Aug 20; 71(2):187-94. PMID: 12927657.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    343. Gonzalez G, Feingold A, Oliveto A, Gonsai K, Kosten TR. Comorbid major depressive disorder as a prognostic factor in cocaine-abusing buprenorphine-maintained patients treated with desipramine and contingency management. Am J Drug Alcohol Abuse. 2003 Aug; 29(3):497-514. PMID: 14510037.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    344. Oliveto A, Benios T, Gonsai K, Feingold A, Poling J, Kosten TR. D-cycloserine-Naloxone interactions in opioid-dependent humans under a novel-response naloxone discrimination procedure. Exp Clin Psychopharmacol. 2003 Aug; 11(3):237-46. PMID: 12940503.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    345. Sofuoglu M, Singha A, Kosten TR, McCance-Katz FE, Petrakis I, Oliveto A. Effects of naltrexone and isradipine, alone or in combination, on cocaine responses in humans. Pharmacol Biochem Behav. 2003 Jul; 75(4):801-8. PMID: 12957222.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    346. Reid MC, Tinetti ME, O'Connor PG, Kosten TR, Concato J. Measuring alcohol consumption among older adults: a comparison of available methods. Am J Addict. 2003 May-Jun; 12(3):211-9. PMID: 12851017.
      Citations: 4     Fields:    Translation:Humans
    347. Kosten TR, O'Connor PG. Management of drug and alcohol withdrawal. N Engl J Med. 2003 May 01; 348(18):1786-95. PMID: 12724485.
      Citations: 121     Fields:    Translation:Humans
    348. George TP, Vessicchio JC, Termine A, Jatlow PI, Kosten TR, O'Malley SS. A preliminary placebo-controlled trial of selegiline hydrochloride for smoking cessation. Biol Psychiatry. 2003 Jan 15; 53(2):136-43. PMID: 12547469.
      Citations: 27     Fields:    Translation:HumansCTClinical Trials
    349. Sofuoglu M, Gonzalez G, Poling J, Kosten TR. Prediction of treatment outcome by baseline urine cocaine results and self-reported cocaine use for cocaine and opioid dependence. Am J Drug Alcohol Abuse. 2003; 29(4):713-27. PMID: 14713135.
      Citations: 30     Fields:    Translation:HumansCTClinical Trials
    350. Kosten TR, Biegel D. Therapeutic vaccines for substance dependence. Expert Rev Vaccines. 2002 Oct; 1(3):363-71. PMID: 12901575.
      Citations: 10     Fields:    Translation:HumansAnimals
    351. Gottschalk PC, Kosten TR. Cerebral perfusion defects in combined cocaine and alcohol dependence. Drug Alcohol Depend. 2002 Sep 01; 68(1):95-104. PMID: 12167555.
      Citations: 18     Fields:    Translation:Humans
    352. George TP, Vessicchio JC, Termine A, Bregartner TA, Feingold A, Rounsaville BJ, Kosten TR. A placebo controlled trial of bupropion for smoking cessation in schizophrenia. Biol Psychiatry. 2002 Jul 01; 52(1):53-61. PMID: 12079730.
      Citations: 82     Fields:    Translation:HumansCTClinical Trials
    353. Kosten TR, George TP. The neurobiology of opioid dependence: implications for treatment. Sci Pract Perspect. 2002 Jul; 1(1):13-20. PMID: 18567959; PMCID: PMC2851054.
      Citations: 86     Fields:    Translation:Humans
    354. Boutros NN, Gelernter J, Gooding DC, Cubells J, Young A, Krystal JH, Kosten T. Sensory gating and psychosis vulnerability in cocaine-dependent individuals: preliminary data. Biol Psychiatry. 2002 Apr 15; 51(8):683-6. PMID: 11955469.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    355. Stine SM, Southwick SM, Petrakis IL, Kosten TR, Charney DS, Krystal JH. Yohimbine-induced withdrawal and anxiety symptoms in opioid-dependent patients. Biol Psychiatry. 2002 Apr 15; 51(8):642-51. PMID: 11955464.
      Citations: 47     Fields:    Translation:HumansCTClinical Trials
    356. Kosten TR, Oliveto A, Sevarino KA, Gonsai K, Feingold A. Ketoconazole increases cocaine and opioid use in methadone maintained patients. Drug Alcohol Depend. 2002 Apr 01; 66(2):173-80. PMID: 11906804.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    357. Kosten TR, George TP, Kosten TA. The potential of dopamine agonists in drug addiction. Expert Opin Investig Drugs. 2002 Apr; 11(4):491-9. PMID: 11922858.
      Citations: 21     Fields:    Translation:Humans
    358. Kosten TR, Rosen M, Bond J, Settles M, Roberts JS, Shields J, Jack L, Fox B. Human therapeutic cocaine vaccine: safety and immunogenicity. Vaccine. 2002 Jan 15; 20(7-8):1196-204. PMID: 11803082.
      Citations: 87     Fields:    Translation:HumansCTClinical Trials
    359. George TP, Vessicchio JC, Termine A, Sahady DM, Head CA, Pepper WT, Kosten TR, Wexler BE. Effects of smoking abstinence on visuospatial working memory function in schizophrenia. Neuropsychopharmacology. 2002 Jan; 26(1):75-85. PMID: 11751034.
      Citations: 68     Fields:    Translation:HumansCTClinical Trials
    360. Kosten TR, Gorelick DA. The Lexington narcotic farm. Am J Psychiatry. 2002 Jan; 159(1):22. PMID: 11772684.
      Citations: 1     Fields:    Translation:Humans
    361. Feingold A, Oliveto A, Schottenfeld R, Kosten TR. Utility of crossover designs in clinical trials: efficacy of desipramine vs. placebo in opioid-dependent cocaine abusers. Am J Addict. 2002; 11(2):111-23. PMID: 12028741.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    362. Gonzalez G, Oliveto A, Kosten TR. Treatment of heroin (diamorphine) addiction: current approaches and future prospects. Drugs. 2002; 62(9):1331-43. PMID: 12076182.
      Citations: 9     Fields:    Translation:Humans
    363. Gottschalk PC, Kosten TR. Isradipine enhancement of cerebral blood flow in abstinent cocaine abusers with and without chronic perfusion deficits. Am J Addict. 2002; 11(3):200-8. PMID: 12202012.
      Citations: 5     Fields:    Translation:Humans
    364. Rosenheck R, Kosten T. Buprenorphine for opiate addiction: potential economic impact. Drug Alcohol Depend. 2001 Aug 01; 63(3):253-62. PMID: 11418229.
      Citations: 11     Fields:    Translation:Humans
    365. Jacobsen LK, Southwick SM, Kosten TR. Substance use disorders in patients with posttraumatic stress disorder: a review of the literature. Am J Psychiatry. 2001 Aug; 158(8):1184-90. PMID: 11481147.
      Citations: 309     Fields:    Translation:HumansAnimals
    366. Fiellin DA, Rosenheck RA, Kosten TR. Office-based treatment for opioid dependence: reaching new patient populations. Am J Psychiatry. 2001 Aug; 158(8):1200-4. PMID: 11481150.
      Citations: 17     Fields:    Translation:Humans
    367. Oliveto A, McCance-Katz FE, Singha A, Petrakis I, Hameedi F, Kosten TR. Effects of cocaine prior to and during bupropion maintenance in cocaine-abusing volunteers. Drug Alcohol Depend. 2001 Jul 01; 63(2):155-67. PMID: 11376920.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    368. McCance-Katz EF, Kosten TA, Kosten TR. Going from the bedside back to the bench with ecopipam: a new strategy for cocaine pharmacotherapy development. Psychopharmacology (Berl). 2001 Jun; 155(4):327-9. PMID: 11441421.
      Citations: 2     Fields:    Translation:Humans
    369. Petry NM, Petrakis I, Trevisan L, Wiredu G, Boutros NN, Martin B, Kosten TR. Contingency management interventions: from research to practice. Am J Psychiatry. 2001 May; 158(5):694-702. PMID: 11329388.
      Citations: 23     Fields:    Translation:Humans
    370. D'Souza DC, Kosten TR. Cannabinoid antagonists: a treatment in search of an illness. Arch Gen Psychiatry. 2001 Apr; 58(4):330-1. PMID: 11296092.
      Citations: 3     Fields:    Translation:Humans
    371. Jacobsen LK, Giedd JN, Kreek MJ, Gottschalk C, Kosten TR. Quantitative medial temporal lobe brain morphology and hypothalamic-pituitary-adrenal axis function in cocaine dependence: a preliminary report. Drug Alcohol Depend. 2001 Mar 01; 62(1):49-56. PMID: 11173167.
      Citations: 7     Fields:    Translation:Humans
    372. Jacobsen LK, Giedd JN, Gottschalk C, Kosten TR, Krystal JH. Quantitative morphology of the caudate and putamen in patients with cocaine dependence. Am J Psychiatry. 2001 Mar; 158(3):486-9. PMID: 11229995.
      Citations: 58     Fields:    Translation:Humans
    373. Stine SM, Grillon CG, Morgan CA, Kosten TR, Charney DS, Krystal JH. Methadone patients exhibit increased startle and cortisol response after intravenous yohimbine. Psychopharmacology (Berl). 2001 Mar; 154(3):274-81. PMID: 11351934.
      Citations: 15     Fields:    Translation:Humans
    374. McCance-Katz EF, Rainey PM, Friedland G, Kosten TR, Jatlow P. Effect of opioid dependence pharmacotherapies on zidovudine disposition. Am J Addict. 2001; 10(4):296-307. PMID: 11783744.
      Citations: 14     Fields:    Translation:HumansPHPublic Health
    375. Sernyak MJ, Kosten TR, Fontana A, Rosenheck R. Neuroleptic use in the treatment of Post-Traumatic Stress Disorder. Psychiatr Q. 2001; 72(3):197-213. PMID: 11467155.
      Citations: 2     Fields:    Translation:Humans
    376. George TP, Ziedonis DM, Feingold A, Pepper WT, Satterburg CA, Winkel J, Rounsaville BJ, Kosten TR. Nicotine transdermal patch and atypical antipsychotic medications for smoking cessation in schizophrenia. Am J Psychiatry. 2000 Nov; 157(11):1835-42. PMID: 11058482.
      Citations: 84     Fields:    Translation:HumansCTClinical Trials
    377. Singha AK, McCance-Katz EF, Petrakis I, Kosten TR, Oliveto A. Sex differences in self-reported and physiological response to oral cocaine and placebo in humans. Am J Drug Alcohol Abuse. 2000 Nov; 26(4):643-57. PMID: 11097197.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    378. Jacobsen LK, Staley JK, Zoghbi SS, Seibyl JP, Kosten TR, Innis RB, Gelernter J. Prediction of dopamine transporter binding availability by genotype: a preliminary report. Am J Psychiatry. 2000 Oct; 157(10):1700-3. PMID: 11007732.
      Citations: 75     Fields:    Translation:HumansCells
    379. Avants SK, Margolin A, Holford TR, Kosten TR. A randomized controlled trial of auricular acupuncture for cocaine dependence. Arch Intern Med. 2000 Aug 14-28; 160(15):2305-12. PMID: 10927727.
      Citations: 28     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    380. Jacobsen LK, Staley JK, Malison RT, Zoghbi SS, Seibyl JP, Kosten TR, Innis RB. Elevated central serotonin transporter binding availability in acutely abstinent cocaine-dependent patients. Am J Psychiatry. 2000 Jul; 157(7):1134-40. PMID: 10873923.
      Citations: 25     Fields:    Translation:Humans
    381. Kosten TR, Fontana A, Sernyak MJ, Rosenheck R. Benzodiazepine use in posttraumatic stress disorder among veterans with substance abuse. J Nerv Ment Dis. 2000 Jul; 188(7):454-9. PMID: 10919705.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    382. Schottenfeld RS, Pakes J, O'Connor P, Chawarski M, Oliveto A, Kosten TR. Thrice-weekly versus daily buprenorphine maintenance. Biol Psychiatry. 2000 Jun 15; 47(12):1072-9. PMID: 10862807.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    383. George TP, Chawarski MC, Pakes J, Carroll KM, Kosten TR, Schottenfeld RS. Disulfiram versus placebo for cocaine dependence in buprenorphine-maintained subjects: a preliminary trial. Biol Psychiatry. 2000 Jun 15; 47(12):1080-6. PMID: 10862808.
      Citations: 59     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    384. Farren CK, Hameedi FA, Rosen MA, Woods S, Jatlow P, Kosten TR. Significant interaction between clozapine and cocaine in cocaine addicts. Drug Alcohol Depend. 2000 May 01; 59(2):153-63. PMID: 10891628.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    385. Sevarino KA, Oliveto A, Kosten TR. Neurobiological adaptations to psychostimulants and opiates as a basis of treatment development. Ann N Y Acad Sci. 2000; 909:51-87. PMID: 10911924.
      Citations: 2     Fields:    Translation:Humans
    386. Gottschalk PC, Jacobsen LK, Kosten TR. Current concepts in pharmacotherapy of substance abuse. Curr Psychiatry Rep. 1999 Dec; 1(2):172-8. PMID: 11122921.
      Citations: 4     Fields:    Translation:Humans
    387. Singha AK, McCance-Katz EF, Heck SA, Kosten TR, Oliveto A. Individual differences in humans responding under a cocaine discrimination procedure: discriminators versus nondiscriminators. Exp Clin Psychopharmacol. 1999 Nov; 7(4):391-8. PMID: 10609974.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    388. Oliveto AH, Feingold A, Schottenfeld R, Jatlow P, Kosten TR. Desipramine in opioid-dependent cocaine abusers maintained on buprenorphine vs methadone. Arch Gen Psychiatry. 1999 Sep; 56(9):812-20. PMID: 12884887.
      Citations: 16     Fields:    Translation:HumansCTClinical Trials
    389. Rosen MI, Kosten TR, Kreek MJ. The effects of naltrexone maintenance on the response to yohimbine in healthy volunteers. Biol Psychiatry. 1999 Jun 15; 45(12):1636-45. PMID: 10376126.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    390. Kosten TR, Woods SW, Rosen MI, Pearsall HR. Interactions of cocaine with nimodipine: a brief report. Am J Addict. 1999; 8(1):77-81. PMID: 10189518.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    391. Kosten TR. Images in psychiatry. Marie Nyswander, 1919-1986. Am J Psychiatry. 1998 Dec; 155(12):1766. PMID: 9842790.
      Citations:    Fields:    Translation:Humans
    392. Kosten TR, Markou A, Koob GF. Depression and stimulant dependence: neurobiology and pharmacotherapy. J Nerv Ment Dis. 1998 Dec; 186(12):737-45. PMID: 9865811.
      Citations: 24     Fields:    Translation:Humans
    393. Avants SK, Margolin A, Kosten TR, Rounsaville BJ, Schottenfeld RS. When is less treatment better? The role of social anxiety in matching methadone patients to psychosocial treatments. J Consult Clin Psychol. 1998 Dec; 66(6):924-31. PMID: 9874905.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    394. Rosen MI, Pearsall HR, Kosten TR. The effect of lamotrigine on naloxone-precipitated opiate withdrawal. Drug Alcohol Depend. 1998 Oct 01; 52(2):173-6. PMID: 9800147.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    395. McCance-Katz EF, Kosten TR, Jatlow P. Disulfiram effects on acute cocaine administration. Drug Alcohol Depend. 1998 Sep 01; 52(1):27-39. PMID: 9788003.
      Citations: 37     Fields:    Translation:HumansCTClinical Trials
    396. McCance-Katz EF, Kosten TR, Jatlow P. Concurrent use of cocaine and alcohol is more potent and potentially more toxic than use of either alone--a multiple-dose study. Biol Psychiatry. 1998 Aug 15; 44(4):250-9. PMID: 9715356.
      Citations: 51     Fields:    Translation:HumansCTClinical Trials
    397. O'Connor PG, Oliveto AH, Shi JM, Triffleman EG, Carroll KM, Kosten TR, Rounsaville BJ, Pakes JA, Schottenfeld RS. A randomized trial of buprenorphine maintenance for heroin dependence in a primary care clinic for substance users versus a methadone clinic. Am J Med. 1998 Aug; 105(2):100-5. PMID: 9727815.
      Citations: 56     Fields:    Translation:HumansCTClinical Trials
    398. Malison RT, Best SE, van Dyck CH, McCance EF, Wallace EA, Laruelle M, Baldwin RM, Seibyl JP, Price LH, Kosten TR, Innis RB. Elevated striatal dopamine transporters during acute cocaine abstinence as measured by [123I] beta-CIT SPECT. Am J Psychiatry. 1998 Jun; 155(6):832-4. PMID: 9619159.
      Citations: 58     Fields:    Translation:Humans
    399. Malison RT, McCance E, Carpenter LL, Baldwin RM, Seibyl JP, Price LH, Kosten TR, Innis RB. [123I]beta-CIT SPECT imaging of dopamine transporter availability after mazindol administration in human cocaine addicts. Psychopharmacology (Berl). 1998 Jun; 137(4):321-5. PMID: 9676890.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    400. Kosten TR. Addiction as a brain disease. Am J Psychiatry. 1998 Jun; 155(6):711-3. PMID: 9619141.
      Citations: 4     Fields:    Translation:Humans
    401. Avants SK, Margolin A, DePhilippis D, Kosten TR. A comprehensive pharmacologic-psychosocial treatment program for HIV-seropositive cocaine- and opioid-dependent patients. Preliminary findings. J Subst Abuse Treat. 1998 May-Jun; 15(3):261-5. PMID: 9633038.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    402. Oliveto AH, Rosen MI, Kosten TA, Hameedi FA, Woods SW, Kosten TR. Hydromorphone-naloxone combinations in opioid-dependent humans under a naloxone novel-response discrimination procedure. Exp Clin Psychopharmacol. 1998 May; 6(2):169-78. PMID: 9608349.
      Citations: 2     Fields:    Translation:Humans
    403. Oliveto AH, McCance-Katz E, Singha A, Hameedi F, Kosten TR. Effects of d-amphetamine and caffeine in humans under a cocaine discrimination procedure. Behav Pharmacol. 1998 May; 9(3):207-17. PMID: 9832935.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    404. Kosten TR, Cheeves C, Palumbo J, Seibyl JP, Price LH, Woods SW. Regional cerebral blood flow during acute and chronic abstinence from combined cocaine-alcohol abuse. Drug Alcohol Depend. 1998 May 01; 50(3):187-95. PMID: 9649971.
      Citations: 11     Fields:    Translation:Humans
    405. McCance-Katz EF, Kosten TR, Jatlow P. Chronic disulfiram treatment effects on intranasal cocaine administration: initial results. Biol Psychiatry. 1998 Apr 01; 43(7):540-3. PMID: 9547934.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    406. Markou A, Kosten TR, Koob GF. Neurobiological similarities in depression and drug dependence: a self-medication hypothesis. Neuropsychopharmacology. 1998 Mar; 18(3):135-74. PMID: 9471114.
      Citations: 240     Fields:    Translation:Animals
    407. Bowers MB, Malison RT, Seibyl JP, Kosten TR. Plasma homovanillic acid and the dopamine transporter during cocaine withdrawal. Biol Psychiatry. 1998 Feb 15; 43(4):278-81. PMID: 9513737.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    408. Margolin A, Avants SK, DePhilippis D, Kosten TR. A preliminary investigation of lamotrigine for cocaine abuse in HIV-seropositive patients. Am J Drug Alcohol Abuse. 1998 Feb; 24(1):85-101. PMID: 9513631.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    409. O'Connor PG, Kosten TR. Rapid and ultrarapid opioid detoxification techniques. JAMA. 1998 Jan 21; 279(3):229-34. PMID: 9438745.
      Citations: 19     Fields:    Translation:Humans
    410. Kosten TR. The pharmacotherapy of relapse prevention using anticonvulsants. Am J Addict. 1998; 7(3):205-9. PMID: 9702288.
      Citations:    Fields:    Translation:Humans
    411. Schottenfeld RS, Pakes JR, Kosten TR. Prognostic factors in Buprenorphine- versus methadone-maintained patients. J Nerv Ment Dis. 1998 Jan; 186(1):35-43. PMID: 9457145.
      Citations: 21     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    412. Kosten TR. Pharmacotherapy of cerebral ischemia in cocaine dependence. Drug Alcohol Depend. 1998 Jan 01; 49(2):133-44. PMID: 9543650.
      Citations: 10     Fields:    Translation:Humans
    413. Oliveto AH, Farren C, Kosten TR. Effect of LAAM dose on opiate use in opioid-dependent patients. A pilot study. Am J Addict. 1998; 7(4):272-82. PMID: 9809131.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    414. Kosten TR, Rosen MI, McMahon TL, Bridge TP, O'Malley SS, Pearsall R, O'Connor PG. Treatment of early AIDS dementia in intravenous drug users: high versus low dose peptide T. Am J Drug Alcohol Abuse. 1997 Nov; 23(4):543-53. PMID: 9366972.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    415. O'Connor PG, Carroll KM, Shi JM, Schottenfeld RS, Kosten TR, Rounsaville BJ. Three methods of opioid detoxification in a primary care setting. A randomized trial. Ann Intern Med. 1997 Oct 01; 127(7):526-30. PMID: 9313020.
      Citations: 39     Fields:    Translation:HumansCTClinical Trials
    416. Avants SK, Margolin A, McMahon TJ, Kosten TR. Association between self-report of cognitive impairment, HIV status, and cocaine use in a sample of cocaine-dependent methadone-maintained patients. Addict Behav. 1997 Sep-Oct; 22(5):599-611. PMID: 9347062.
      Citations: 13     Fields:    Translation:Humans
    417. Schottenfeld RS, Pakes JR, Oliveto A, Ziedonis D, Kosten TR. Buprenorphine vs methadone maintenance treatment for concurrent opioid dependence and cocaine abuse. Arch Gen Psychiatry. 1997 Aug; 54(8):713-20. PMID: 9283506.
      Citations: 65     Fields:    Translation:HumansCTClinical Trials
    418. Stine SM, Krystal JH, Petrakis IL, Jatlow PI, Heninger GR, Kosten TR, Charney DS. Effect of alpha-methyl-para-tyrosine on response to cocaine challenge. Biol Psychiatry. 1997 Aug 01; 42(3):181-90. PMID: 9232210.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    419. Warner EA, Kosten TR, O'Connor PG. Pharmacotherapy for opioid and cocaine abuse. Med Clin North Am. 1997 Jul; 81(4):909-25. PMID: 9222260.
      Citations: 7     Fields:    Translation:Humans
    420. Hameedi FA, Woods SW, Rosen MI, Pearsall HR, Kosten TR. Dose dependent effects of yohimbine on methadone maintained patients. Am J Drug Alcohol Abuse. 1997 May; 23(2):327-33. PMID: 9143642.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    421. Margolin A, Avants SK, Rounsaville B, Kosten TR, Schottenfeld RS. Motivational factors in cocaine pharmacotherapy trials with methadone-maintained patients: problems and paradoxes. J Psychoactive Drugs. 1997 Apr-Jun; 29(2):205-12. PMID: 9250948.
      Citations: 1     Fields:    Translation:Humans
    422. Rosen MI, Pearsall HR, Woods SW, Kosten TR. Effects of gamma-hydroxybutyric acid (GHB) in opioid-dependent patients. J Subst Abuse Treat. 1997 Mar-Apr; 14(2):149-54. PMID: 9258859.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    423. Manji H, Chen G, Potter W, Kosten TR. Guanine nucleotide binding proteins in opioid-dependent patients. Biol Psychiatry. 1997 Jan 15; 41(2):130-4. PMID: 9018382.
      Citations: 3     Fields:    Translation:HumansCells
    424. Kosten TR, Ziedonis DM. Substance abuse and schizophrenia: editors' introduction. Schizophr Bull. 1997; 23(2):181-6. PMID: 9165628.
      Citations: 4     Fields:    Translation:Humans
    425. Silverman DG, Kosten TR, Jatlow PI, Gutter V, Fleming J, O'Connor TZ, Byck R. Decreased digital flow persists after the abatement of cocaine-induced hemodynamic stimulation. Anesth Analg. 1997 Jan; 84(1):46-50. PMID: 8988997.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    426. van Dyck CH, McMahon TJ, Rosen MI, O'Malley SS, O'Connor PG, Lin CH, Pearsall HR, Woods SW, Kosten TR. Sustained-release methylphenidate for cognitive impairment in HIV-1-infected drug abusers: a pilot study. J Neuropsychiatry Clin Neurosci. 1997; 9(1):29-36. PMID: 9017526.
      Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
    427. O'Connor PG, Oliveto AH, Shi JM, Triffleman E, Carroll KM, Kosten TR, Rounsaville BJ. A pilot study of primary-care-based buprenorphine maintenance for heroin dependence. Am J Drug Alcohol Abuse. 1996 Nov; 22(4):523-31. PMID: 8911590.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    428. Wallace EA, Wisniewski G, Zubal G, vanDyck CH, Pfau SE, Smith EO, Rosen MI, Sullivan MC, Woods SW, Kosten TR. Acute cocaine effects on absolute cerebral blood flow. Psychopharmacology (Berl). 1996 Nov; 128(1):17-20. PMID: 8944401.
      Citations: 18     Fields:    Translation:HumansCTClinical Trials
    429. Margolin A, Avants SK, Kosten TR. Abstinence symptomatology associated with cessation of chronic cocaine abuse among methadone-maintained patients. Am J Drug Alcohol Abuse. 1996 Aug; 22(3):377-88. PMID: 8841686.
      Citations: 5     Fields:    Translation:Humans
    430. Rosen MI, McMahon TJ, Woods SW, Pearsall HR, Kosten TR. A pilot study of dextromethorphan in naloxone-precipitated opiate withdrawal. Eur J Pharmacol. 1996 Jul 04; 307(3):251-7. PMID: 8836612.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    431. Margolin A, Avants SK, Kosten TR. Pemoline for the treatment of cocaine dependence in methadone-maintained patients. J Psychoactive Drugs. 1996 Jul-Sep; 28(3):301-4. PMID: 8895115.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    432. Rosen MI, Pearsall HR, Woods SW, Kosten TR. The effect of gamma-hydroxybutyric acid on naloxone-precipitated opiate withdrawal. Neuropsychopharmacology. 1996 Mar; 14(3):187-93. PMID: 8866702.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    433. Rosen MI, McMahon TJ, Hameedi FA, Pearsall HR, Woods SW, Kreek MJ, Kosten TR. Effect of clonidine pretreatment on naloxone-precipitated opiate withdrawal. J Pharmacol Exp Ther. 1996 Mar; 276(3):1128-35. PMID: 8786543.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    434. Kosten TR, Kosten TA, McDougle CJ, Hameedi FA, McCance EF, Rosen MI, Oliveto AH, Price LH. Gender differences in response to intranasal cocaine administration to humans. Biol Psychiatry. 1996 Jan 15; 39(2):147-8. PMID: 8717615.
      Citations: 35     Fields:    Translation:Humans
    435. Margolin A, Kosten TR, Avants SK, Wilkins J, Ling W, Beckson M, Arndt IO, Cornish J, Ascher JA, Li SH, et al. A multicenter trial of bupropion for cocaine dependence in methadone-maintained patients. Drug Alcohol Depend. 1995 Dec; 40(2):125-31. PMID: 8745134.
      Citations: 44     Fields:    Translation:HumansCTClinical Trials
    436. Oliveto A, Kosten TR, Schottenfeld R, Falcioni J, Ziedonis D. Desipramine, amantadine, or fluoxetine in buprenorphine-maintained cocaine users. J Subst Abuse Treat. 1995 Nov-Dec; 12(6):423-8. PMID: 8749726.
      Citations: 5     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    437. Rosen MI, McMahon TJ, Margolin A, Gill TS, Woods SW, Pearsall HR, Kreek MJ, Kosten TR. Reliability of sequential naloxone challenge tests. Am J Drug Alcohol Abuse. 1995 Nov; 21(4):453-67. PMID: 8561097.
      Citations: 2     Fields:    Translation:Humans
    438. Margolin A, Avants SK, Kosten TR. Mazindol for relapse prevention to cocaine abuse in methadone-maintained patients. Am J Drug Alcohol Abuse. 1995 Nov; 21(4):469-81. PMID: 8561098.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    439. Stine SM, Krystal JH, Kosten TR, Charney DS. Mazindol treatment for cocaine dependence. Drug Alcohol Depend. 1995 Oct; 39(3):245-52. PMID: 8556974.
      Citations: 13     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    440. McCance EF, Price LH, Kosten TR, Jatlow PI. Cocaethylene: pharmacology, physiology and behavioral effects in humans. J Pharmacol Exp Ther. 1995 Jul; 274(1):215-23. PMID: 7616402.
      Citations: 23     Fields:    Translation:HumansCTClinical Trials
    441. Avants SK, Margolin A, Chang P, Kosten TR, Birch S. Acupuncture for the treatment of cocaine addiction. Investigation of a needle puncture control. J Subst Abuse Treat. 1995 May-Jun; 12(3):195-205. PMID: 7474027.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    442. Satel SL, Krystal JH, Delgado PL, Kosten TR, Charney DS. Tryptophan depletion and attenuation of cue-induced craving for cocaine. Am J Psychiatry. 1995 May; 152(5):778-83. PMID: 7726319.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    443. Aronson SC, Black JE, McDougle CJ, Scanley BE, Jatlow P, Kosten TR, Heninger GR, Price LH. Serotonergic mechanisms of cocaine effects in humans. Psychopharmacology (Berl). 1995 May; 119(2):179-85. PMID: 7659765.
      Citations: 16     Fields:    Translation:HumansCTClinical Trials
    444. Hameedi FA, Rosen MI, McCance-Katz EF, McMahon TJ, Price LH, Jatlow PI, Woods SW, Kosten TR. Behavioral, physiological, and pharmacological interaction of cocaine and disulfiram in humans. Biol Psychiatry. 1995 Apr 15; 37(8):560-3. PMID: 7619981.
      Citations: 31     Fields:    Translation:HumansCTClinical Trials
    445. Kosten TR, Rayford BS. Effects of ethnicity on low-dose opiate stabilization. J Subst Abuse Treat. 1995 Mar-Apr; 12(2):111-6. PMID: 7623388.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    446. Avants SK, Margolin A, Kosten TR, Cooney NL. Differences between responders and nonresponders to cocaine cues in the laboratory. Addict Behav. 1995 Mar-Apr; 20(2):215-24. PMID: 7484315.
      Citations: 36     Fields:    Translation:Humans
    447. Krystal JH, Woods SW, Kosten TR, Rosen MI, Seibyl JP, van Dyck CC, Price LH, Zubal IG, Hoffer PB, Charney DS. Opiate dependence and withdrawal: preliminary assessment using single photon emission computerized tomography (SPECT). Am J Drug Alcohol Abuse. 1995 Feb; 21(1):47-63. PMID: 7762544.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    448. Margolin A, Avants SK, Chang P, Birch S, Kosten TR. A single-blind investigation of four auricular needle puncture configurations. Am J Chin Med. 1995; 23(2):105-14. PMID: 7572770.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    449. Lago JA, Kosten TR. Stimulant withdrawal. Addiction. 1994 Nov; 89(11):1477-81. PMID: 7841859.
      Citations: 17     Fields:    Translation:HumansAnimals
    450. Stine SM, Kosten TR. Reduction of opiate withdrawal-like symptoms by cocaine abuse during methadone and buprenorphine maintenance. Am J Drug Alcohol Abuse. 1994 Nov; 20(4):445-58. PMID: 7832179.
      Citations: 4     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    451. Margolin A, Avants SK, Kosten TR. Cue-elicited cocaine craving and autogenic relaxation. Association with treatment outcome. J Subst Abuse Treat. 1994 Nov-Dec; 11(6):549-52. PMID: 7884838.
      Citations: 6     Fields:    Translation:Humans
    452. Meandzija B, O'Connor PG, Fitzgerald B, Rounsaville BJ, Kosten TR. HIV infection and cocaine use in methadone maintained and untreated intravenous drug users. Drug Alcohol Depend. 1994 Oct; 36(2):109-13. PMID: 7851277.
      Citations: 15     Fields:    Translation:Humans
    453. McDougle CJ, Black JE, Malison RT, Zimmermann RC, Kosten TR, Heninger GR, Price LH. Noradrenergic dysregulation during discontinuation of cocaine use in addicts. Arch Gen Psychiatry. 1994 Sep; 51(9):713-9. PMID: 8080348.
      Citations: 41     Fields:    Translation:HumansCTClinical Trials
    454. Rinder HM, Ault KA, Jatlow PI, Kosten TR, Smith BR. Platelet alpha-granule release in cocaine users. Circulation. 1994 Sep; 90(3):1162-7. PMID: 7522132.
      Citations: 18     Fields:    Translation:HumansCellsCTClinical Trials
    455. Avants SK, Margolin A, Kosten TR. Cocaine abuse in methadone maintenance programs: integrating pharmacotherapy with psychosocial interventions. J Psychoactive Drugs. 1994 Apr-Jun; 26(2):137-46. PMID: 7931858.
      Citations: 2     Fields:    Translation:Humans
    456. Rosen MI, Wallace EA, McMahon TJ, Pearsall HR, Woods SW, Price LH, Kosten TR. Buprenorphine: duration of blockade of effects of intramuscular hydromorphone. Drug Alcohol Depend. 1994 Apr; 35(2):141-9. PMID: 7519977.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    457. Ziedonis DM, Kosten TR, Glazer WM, Frances RJ. Nicotine dependence and schizophrenia. Hosp Community Psychiatry. 1994 Mar; 45(3):204-6. PMID: 7910577.
      Citations: 63     Fields:    Translation:Humans
    458. Avants SK, Margolin A, Kosten TR, Singer JL. Changes concurrent with initiation of abstinence from cocaine abuse. J Subst Abuse Treat. 1993 Nov-Dec; 10(6):577-83. PMID: 8308943.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    459. Sellers EM, Ciraulo DA, DuPont RL, Griffiths RR, Kosten TR, Romach MK, Woody GE. Alprazolam and benzodiazepine dependence. J Clin Psychiatry. 1993 Oct; 54 Suppl:64-75; discussion 76-7. PMID: 8262891.
      Citations: 12     Fields:    Translation:HumansPHPublic Health
    460. Schottenfeld RS, Pakes J, Ziedonis D, Kosten TR. Buprenorphine: dose-related effects on cocaine and opioid use in cocaine-abusing opioid-dependent humans. Biol Psychiatry. 1993 Jul 1-15; 34(1-2):66-74. PMID: 8373940.
      Citations: 31     Fields:    Translation:Humans
    461. Kosten TR, Schottenfeld R, Ziedonis D, Falcioni J. Buprenorphine versus methadone maintenance for opioid dependence. J Nerv Ment Dis. 1993 Jun; 181(6):358-64. PMID: 8501457.
      Citations: 38     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    462. Satel SL, Kosten TR, Schuckit MA, Fischman MW. Should protracted withdrawal from drugs be included in DSM-IV? Am J Psychiatry. 1993 May; 150(5):695-704. PMID: 8097618.
      Citations: 30     Fields:    Translation:Humans
    463. Margolin A, Chang P, Avants SK, Kosten TR. Effects of sham and real auricular needling: implications for trials of acupuncture for cocaine addiction. Am J Chin Med. 1993; 21(2):103-11. PMID: 8237887.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    464. Kosten TR. Clinical and research perspectives on cocaine abuse: the pharmacotherapy of cocaine abuse. NIDA Res Monogr. 1993; 135:48-56. PMID: 8289903.
      Citations: 1     Fields:    Translation:Humans
    465. Kosten TA, Gawin FH, Kosten TR, Rounsaville BJ. Gender differences in cocaine use and treatment response. J Subst Abuse Treat. 1993 Jan-Feb; 10(1):63-6. PMID: 8450576.
      Citations: 92     Fields:    Translation:HumansCTClinical Trials
    466. McCance-Katz EF, Price LH, McDougle CJ, Kosten TR, Black JE, Jatlow PI. Concurrent cocaine-ethanol ingestion in humans: pharmacology, physiology, behavior, and the role of cocaethylene. Psychopharmacology (Berl). 1993; 111(1):39-46. PMID: 7870932.
      Citations: 33     Fields:    Translation:HumansCTClinical Trials
    467. Kosten TR, Morgan CM, Falcione J, Schottenfeld RS. Pharmacotherapy for cocaine-abusing methadone-maintained patients using amantadine or desipramine. Arch Gen Psychiatry. 1992 Nov; 49(11):894-8. PMID: 1444728.
      Citations: 17     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    468. Kosten TR, Morgan C, Kreek MJ. Beta endorphin levels during heroin, methadone, buprenorphine, and naloxone challenges: preliminary findings. Biol Psychiatry. 1992 Sep 15; 32(6):523-8. PMID: 1445968.
      Citations: 3     Fields:    Translation:Humans
    469. McDougle CJ, Price LH, Palumbo JM, Kosten TR, Heninger GR, Kleber HD. Dopaminergic responsivity during cocaine abstinence: a pilot study. Psychiatry Res. 1992 Jul; 43(1):77-85. PMID: 1359594.
      Citations: 6     Fields:    Translation:Humans
    470. Stine SM, Kosten TR. Use of drug combinations in treatment of opioid withdrawal. J Clin Psychopharmacol. 1992 Jun; 12(3):203-9. PMID: 1629388.
      Citations: 5     Fields:    Translation:Humans
    471. Kosten TR. Pharmacological approaches to cocaine dependence. Clin Neuropharmacol. 1992; 15 Suppl 1 Pt A:70A-71A. PMID: 1498999.
      Citations: 1     Fields:    Translation:HumansAnimals
    472. Kosten TA, Bianchi MS, Kosten TR. The predictive validity of the dependence syndrome in opiate abusers. Am J Drug Alcohol Abuse. 1992; 18(2):145-56. PMID: 1562012.
      Citations: 1     Fields:    Translation:Humans
    473. Closser MH, Kosten TR. Alcohol and cocaine abuse. A comparison of epidemiology and clinical characteristics. Recent Dev Alcohol. 1992; 10:115-28. PMID: 1317046.
      Citations: 5     Fields:    Translation:Humans
    474. Kosten TR, Morgan C, Kleber HD. Phase II clinical trials of buprenorphine: detoxification and induction onto naltrexone. NIDA Res Monogr. 1992; 121:101-19. PMID: 1406906.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    475. Krystal JH, McDougle CJ, Kosten TR, Price LH, Aghajanian GK, Charney DS. Baclofen-assisted detoxification from opiates. A pilot study. J Subst Abuse Treat. 1992; 9(2):139-42. PMID: 1324986.
      Citations: 2     Fields:    Translation:Humans
    476. Nigam R, Schottenfeld R, Kosten TR. Treatment of dual diagnosis patients: a relapse prevention group approach. J Subst Abuse Treat. 1992; 9(4):305-9. PMID: 1362227.
      Citations: 1     Fields:    Translation:Humans
    477. Chang G, Carroll KM, Behr HM, Kosten TR. Improving treatment outcome in pregnant opiate-dependent women. J Subst Abuse Treat. 1992; 9(4):327-30. PMID: 1479630; PMCID: PMC3677856.
      Citations: 14     Fields:    Translation:HumansPHPublic Health
    478. Kosten TR, Rosen MI, Schottenfeld R, Ziedonis D. Buprenorphine for cocaine and opiate dependence. Psychopharmacol Bull. 1992; 28(1):15-9. PMID: 1609037.
      Citations: 9     Fields:    Translation:Humans
    479. Kosten TR, Kosten TA, Rounsaville BJ. Alcoholism and depressive disorders in opioid addicts and their family members. Compr Psychiatry. 1991 Nov-Dec; 32(6):521-7. PMID: 1778079.
      Citations:    Fields:    Translation:Humans
    480. Kosten TA, Kosten TR. Pharmacological blocking agents for treating substance abuse. J Nerv Ment Dis. 1991 Oct; 179(10):583-92. PMID: 1919542.
      Citations: 6     Fields:    Translation:HumansAnimals
    481. Ziedonis DM, Kosten TR. Pharmacotherapy improves treatment outcome in depressed cocaine addicts. J Psychoactive Drugs. 1991 Oct-Dec; 23(4):417-25. PMID: 1813613.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    482. Kosten TR, Rounsaville BJ, Kosten TA, Merikangas K. Gender differences in the specificity of alcoholism transmission among the relatives of opioid addicts. J Nerv Ment Dis. 1991 Jul; 179(7):392-400. PMID: 1869867.
      Citations: 3     Fields:    Translation:Humans
    483. Kosten TR, Frank JB, Dan E, McDougle CJ, Giller EL. Pharmacotherapy for posttraumatic stress disorder using phenelzine or imipramine. J Nerv Ment Dis. 1991 Jun; 179(6):366-70. PMID: 2051152.
      Citations: 34     Fields:    Translation:HumansCTClinical Trials
    484. Kosten TR, Morgan C, Kleber HD. Treatment of heroin addicts using buprenorphine. Am J Drug Alcohol Abuse. 1991 Jun; 17(2):119-28. PMID: 1862786.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    485. Rosen MI, Kosten TR. Buprenorphine: beyond methadone? Hosp Community Psychiatry. 1991 Apr; 42(4):347-9. PMID: 2050347.
      Citations: 3     Fields:    Translation:Humans
    486. Kosten TR. Medications development and the war on drugs: victims of the Gulf war? Biol Psychiatry. 1991 Mar 15; 29(6):521-3. PMID: 2054428.
      Citations:    Fields:    Translation:Humans
    487. Mason JW, Kosten TR, Giller EL. Multidimensional hormonal discrimination of paranoid schizophrenic from bipolar manic patients. Biol Psychiatry. 1991 Mar 01; 29(5):457-66. PMID: 2018819.
      Citations: 3     Fields:    Translation:Humans
    488. Kosten TR. Client issues in drug abuse treatment: addressing multiple drug abuse. NIDA Res Monogr. 1991; 106:136-51. PMID: 1922284.
      Citations: 3     Fields:    Translation:Humans
    489. Rounsaville BJ, Kosten TR, Weissman MM, Prusoff B, Pauls D, Anton SF, Merikangas K. Psychiatric disorders in relatives of probands with opiate addiction. Arch Gen Psychiatry. 1991 Jan; 48(1):33-42. PMID: 1984760.
      Citations: 33     Fields:    Translation:Humans
    490. Woods SW, O'Malley SS, Martini BL, McDougle CJ, Price LH, Krystal JH, Hoffer PB, Kosten TR. SPECT regional cerebral blood flow and neuropsychological testing in non-demented HIV-positive drug abusers: preliminary results. Prog Neuropsychopharmacol Biol Psychiatry. 1991; 15(5):649-62. PMID: 1956993.
      Citations: 3     Fields:    Translation:Humans
    491. Ziedonis DM, Kosten TR. Depression as a prognostic factor for pharmacological treatment of cocaine dependence. Psychopharmacol Bull. 1991; 27(3):337-43. PMID: 1775608.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    492. Kosten TR, Wahby V, Giller E, Mason J. The dexamethasone suppression test and thyrotropin-releasing hormone stimulation test in posttraumatic stress disorder. Biol Psychiatry. 1990 Oct 15; 28(8):657-64. PMID: 2122916.
      Citations: 4     Fields:    Translation:Humans
    493. Kosten TR, Gawin FH, Morgan C, Nelson JC, Jatlow P. Desipramine and its 2-hydroxy metabolite in patients taking or not taking methadone. Am J Psychiatry. 1990 Oct; 147(10):1379-80. PMID: 2400009.
      Citations: 3     Fields:    Translation:HumansCells
    494. Kosten TR. Neurobiology of abused drugs. Opioids and stimulants. J Nerv Ment Dis. 1990 Apr; 178(4):217-27. PMID: 2156952.
      Citations: 8     Fields:    Translation:HumansCells
    495. Frank JB, Kosten TR, Giller EL. Antidepressants in the treatment of PTSD. Am J Psychiatry. 1990 Feb; 147(2):260. PMID: 2301678.
      Citations:    Fields:    Translation:Humans
    496. Kosten TR, Krystal JH, Charney DS, Price LH, Morgan CH, Kleber HD. Opioid antagonist challenges in buprenorphine maintained patients. Drug Alcohol Depend. 1990 Feb; 25(1):73-8. PMID: 2323312.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    497. Kosten TA, Kosten TR. The dependence syndrome concept as applied to alcohol and other substances of abuse. Recent Dev Alcohol. 1990; 8:47-68. PMID: 2185524.
      Citations:    Fields:    Translation:HumansAnimals
    498. Kosten TR, Bryant K, Rounsaville BJ. The SCID: a clinical instrument for assessing psychiatric disorders. NIDA Res Monogr. 1990; 105:213-9. PMID: 1876002.
      Citations: 2     Fields:    Translation:Humans
    499. Kosten TR, Morgan C, Kosten TA. Depressive symptoms during buprenorphine treatment of opioid abusers. J Subst Abuse Treat. 1990; 7(1):51-4. PMID: 2313769.
      Citations: 29     Fields:    Translation:Humans
    500. Diakogiannis IA, Steinberg M, Kosten TR. Mazindol treatment of cocaine abuse. A double-blind investigation. NIDA Res Monogr. 1990; 105:514. PMID: 1876105.
      Citations: 1     Fields:    Translation:Humans
    501. Kosten TR, Gawin FH, Morgan C, Nelson JC, Jatlow P. Evidence for altered desipramine disposition in methadone-maintained patients treated for cocaine abuse. Am J Drug Alcohol Abuse. 1990; 16(3-4):329-36. PMID: 2288330.
      Citations: 2     Fields:    Translation:Humans
    502. Kosten TA, Kosten TR, Rounsaville BJ. Cocaine symptoms are predicted by familial psychopathology. NIDA Res Monogr. 1990; 105:603-4. PMID: 1876139.
      Citations:    Fields:    Translation:Humans
    503. Kosten TR, Krystal JH, Charney DS, Price LH, Morgan CH, Kleber HD. Rapid detoxification from opioid dependence. Am J Psychiatry. 1989 Oct; 146(10):1349. PMID: 2675644.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    504. Kosten TA, Kosten TR. Cocaine abuse and opioid withdrawal. Lancet. 1989 Jul 15; 2(8655):165-6. PMID: 2567937.
      Citations: 5     Fields:    Translation:Humans
    505. Kosten TR. Pharmacotherapeutic interventions for cocaine abuse. Matching patients to treatments. J Nerv Ment Dis. 1989 Jul; 177(7):379-89. PMID: 2664072.
      Citations: 2     Fields:    Translation:Humans
    506. Mason JW, Kennedy JL, Kosten TR, Giller EL. Serum thyroxine levels in schizophrenic and affective disorder diagnostic subgroups. J Nerv Ment Dis. 1989 Jun; 177(6):351-8. PMID: 2723624.
      Citations: 4     Fields:    Translation:Humans
    507. Gawin FH, Kleber HD, Byck R, Rounsaville BJ, Kosten TR, Jatlow PI, Morgan C. Desipramine facilitation of initial cocaine abstinence. Arch Gen Psychiatry. 1989 Feb; 46(2):117-21. PMID: 2492422.
      Citations: 35     Fields:    Translation:HumansCTClinical Trials
    508. Jacobsen LK, Kosten TR. Naloxone challenge as a biological predictor of treatment outcome in opiate addicts. Am J Drug Alcohol Abuse. 1989; 15(4):355-66. PMID: 2596440.
      Citations: 1     Fields:    Translation:Humans
    509. Kosten TA, Kosten TR, Rounsaville BJ. Personality disorders in opiate addicts show prognostic specificity. J Subst Abuse Treat. 1989; 6(3):163-8. PMID: 2795705.
      Citations: 15     Fields:    Translation:Humans
    510. Southwick S, Mason JW, Giller EL, Kosten TR. Serum thyroxine change and clinical recovery in psychiatric inpatients. Biol Psychiatry. 1989 Jan; 25(1):67-74. PMID: 2912510.
      Citations: 5     Fields:    Translation:Humans
    511. Kosten TA, Jacobsen LK, Kosten TR. Severity of precipitated opiate withdrawal predicts drug dependence by DSM-III-R criteria. Am J Drug Alcohol Abuse. 1989; 15(3):237-50. PMID: 2763981.
      Citations: 2     Fields:    Translation:Humans
    512. Kosten TR, Kleber HD, Morgan C. Role of opioid antagonists in treating intravenous cocaine abuse. Life Sci. 1989; 44(13):887-92. PMID: 2927249.
      Citations: 20     Fields:    Translation:Humans
    513. Kosten TR, Rounsaville BJ, Foley SH. Inpatient vs. outpatient cocaine abuse treatments. NIDA Res Monogr. 1989; 95:312-3. PMID: 2640976.
      Citations:    Fields:    Translation:Humans
    514. Kosten TR, Morgan CJ, Kleber HD. Buprenorphine treatment of cocaine abuse. NIDA Res Monogr. 1989; 95:461. PMID: 2641031.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    515. Gawin FH, Morgan C, Kosten TR, Kleber HD. Double-blind evaluation of the effect of acute amantadine on cocaine craving. Psychopharmacology (Berl). 1989; 97(3):402-3. PMID: 2497490.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    516. Frank JB, Kosten TR, Giller EL, Dan E. A randomized clinical trial of phenelzine and imipramine for posttraumatic stress disorder. Am J Psychiatry. 1988 Oct; 145(10):1289-91. PMID: 3048121.
      Citations: 20     Fields:    Translation:HumansCTClinical Trials
    517. Mason JW, Giller EL, Kosten TR, Harkness L. Elevation of urinary norepinephrine/cortisol ratio in posttraumatic stress disorder. J Nerv Ment Dis. 1988 Aug; 176(8):498-502. PMID: 3404142.
      Citations: 22     Fields:    Translation:Humans
    518. Vining E, Kosten TR, Kleber HD. Clinical utility of rapid clonidine-naltrexone detoxification for opioid abusers. Br J Addict. 1988 May; 83(5):567-75. PMID: 3382815.
      Citations: 13     Fields:    Translation:Humans
    519. Kosten TR, Rounsaville BJ, Kleber HD. Antecedents and consequences of cocaine abuse among opioid addicts. A 2.5-year follow-up. J Nerv Ment Dis. 1988 Mar; 176(3):176-81. PMID: 3343591.
      Citations: 14     Fields:    Translation:Humans
    520. Mason JW, Giller EL, Kosten TR. Serum testosterone differences between patients with schizophrenia and those with affective disorder. Biol Psychiatry. 1988 Feb 15; 23(4):357-66. PMID: 3342266.
      Citations: 7     Fields:    Translation:Humans
    521. Kosten TR, Rounsaville BJ. Suicidality among opioid addicts: 2.5 year follow-up. Am J Drug Alcohol Abuse. 1988; 14(3):357-69. PMID: 3189257.
      Citations: 7     Fields:    Translation:Humans
    522. Kosten TR, Kleber HD. Rapid death during cocaine abuse: a variant of the neuroleptic malignant syndrome? Am J Drug Alcohol Abuse. 1988; 14(3):335-46. PMID: 3055940.
      Citations: 8     Fields:    Translation:Humans
    523. Kosten TR, Kleber HD. Differential diagnosis of psychiatric comorbidity in substance abusers. J Subst Abuse Treat. 1988; 5(4):201-6. PMID: 3216436.
      Citations: 5     Fields:    Translation:Humans
    524. Kosten TR, Kleber HD. Buprenorphine detoxification from opioid dependence: a pilot study. Life Sci. 1988; 42(6):635-41. PMID: 3276999.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    525. Kosten TR, Rounsaville BJ, Babor TF, Spitzer RL, Williams JB. Substance-use disorders in DSM-III-R. Evidence for the dependence syndrome across different psychoactive substances. Br J Psychiatry. 1987 Dec; 151:834-43. PMID: 2901887.
      Citations: 14     Fields:    Translation:Humans
    526. Kosten TR, Schumann B, Wright D, Carney MK, Gawin FH. A preliminary study of desipramine in the treatment of cocaine abuse in methadone maintenance patients. J Clin Psychiatry. 1987 Nov; 48(11):442-4. PMID: 3680185.
      Citations: 4     Fields:    Translation:Humans
    527. Kosten TR, Kreek MJ, Swift C, Carney MK, Ferdinands L. Beta endorphin levels in CSF during methadone maintenance. Life Sci. 1987 Aug 31; 41(9):1071-6. PMID: 2956475.
      Citations: 8     Fields:    Translation:Humans
    528. Rounsaville BJ, Kosten TR, Williams JB, Spitzer RL. A field trial of DSM-III-R psychoactive substance dependence disorders. Am J Psychiatry. 1987 Mar; 144(3):351-5. PMID: 3826436.
      Citations: 2     Fields:    Translation:Humans
    529. Kosten TR, Rounsaville BJ, Kleber HD. A 2.5-year follow-up of cocaine use among treated opioid addicts. Have our treatments helped? Arch Gen Psychiatry. 1987 Mar; 44(3):281-4. PMID: 3827521.
      Citations: 24     Fields:    Translation:Humans
    530. Jacobs SC, Mason J, Kosten TR, Kasl SV, Ostfeld AM, Wahby V. Urinary free cortisol and separation anxiety early in the course of bereavement and threatened loss. Biol Psychiatry. 1987 Feb; 22(2):148-52. PMID: 3814667.
      Citations: 4     Fields:    Translation:Humans
    531. Rounsaville BJ, Kosten TR, Kleber HD. The antecedents and benefits of achieving abstinence in opioid addicts: a 2.5-year follow-up study. Am J Drug Alcohol Abuse. 1987; 13(3):213-29. PMID: 3687888.
      Citations: 8     Fields:    Translation:Humans
    532. Kosten TR, Rounsaville BJ. Source of income as a predictor in opioid addicts: 2.5 year follow-up. NIDA Res Monogr. 1987; 76:196-9. PMID: 3125447.
      Citations:    Fields:    Translation:Humans
    533. Kosten TR, Rounsaville BJ, Babor TF, Spitzer RL, Williams JB. The dependence syndrome across different psychoactive substances: revised DSM-III. NIDA Res Monogr. 1987; 76:255-8. PMID: 3125454.
      Citations:    Fields:    Translation:HumansAnimals
    534. Kosten TR, Jalali B, Steidl JH, Kleber HD. Relationship of marital structure and interactions to opiate abuse relapse. Am J Drug Alcohol Abuse. 1987; 13(4):387-99. PMID: 3687898.
      Citations: 6     Fields:    Translation:Humans
    535. Kosten TR, Mason JW, Giller EL, Ostroff RB, Harkness L. Sustained urinary norepinephrine and epinephrine elevation in post-traumatic stress disorder. Psychoneuroendocrinology. 1987; 12(1):13-20. PMID: 3588809.
      Citations: 44     Fields:    Translation:Animals
    536. Kosten TR, Rounsaville BJ, Kleber HD. Predictors of 2.5-year outcome in opioid addicts: pretreatment source of income. Am J Drug Alcohol Abuse. 1987; 13(1-2):19-32. PMID: 3687883.
      Citations: 1     Fields:    Translation:Humans
    537. Kosten TR, Rounsaville BJ, Kleber HD. Multidimensionality and prediction of treatment outcome in opioid addicts: 2.5-year follow-up. Compr Psychiatry. 1987 Jan-Feb; 28(1):3-13. PMID: 3802797.
      Citations: 3     Fields:    Translation:Humans
    538. Kosten TR, Forrest JN. Treatment of severe lithium-induced polyuria with amiloride. Am J Psychiatry. 1986 Dec; 143(12):1563-8. PMID: 3538913.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    539. Rounsaville BJ, Kosten TR, Kleber HD. Long-term changes in current psychiatric diagnoses of treated opiate addicts. Compr Psychiatry. 1986 Sep-Oct; 27(5):480-98. PMID: 3757496.
      Citations: 5     Fields:    Translation:HumansAnimals
    540. Kosten TR, Rounsaville BJ. Psychopathology in opioid addicts. Psychiatr Clin North Am. 1986 Sep; 9(3):515-32. PMID: 3774603.
      Citations: 2     Fields:    Translation:Humans
    541. Rounsaville BJ, Kosten TR, Weissman MM, Kleber HD. Prognostic significance of psychopathology in treated opiate addicts. A 2.5-year follow-up study. Arch Gen Psychiatry. 1986 Aug; 43(8):739-45. PMID: 3729668.
      Citations: 54     Fields:    Translation:Humans
    542. Kosten TR, Kreek MJ, Ragunath J, Kleber HD. A preliminary study of beta endorphin during chronic naltrexone maintenance treatment in ex-opiate addicts. Life Sci. 1986 Jul 07; 39(1):55-9. PMID: 2941636.
      Citations: 14     Fields:    Translation:Humans
    543. Rounsaville BJ, Kosten TR, Weissmann MM, Kleber HD. A 2.5-year follow-up of short-term interpersonal psychotherapy in methadone-maintained opiate addicts. Compr Psychiatry. 1986 May-Jun; 27(3):201-10. PMID: 3709134.
      Citations: 3     Fields:    Translation:Humans
    544. Mason JW, Giller EL, Kosten TR, Ostroff RB, Podd L. Urinary free-cortisol levels in posttraumatic stress disorder patients. J Nerv Ment Dis. 1986 Mar; 174(3):145-9. PMID: 3950596.
      Citations: 77     Fields:    Translation:Humans
    545. Kosten TR, Kreek MJ, Ragunath J, Kleber HD. Cortisol levels during chronic naltrexone maintenance treatment in ex-opiate addicts. Biol Psychiatry. 1986 Feb; 21(2):217-20. PMID: 3947698.
      Citations: 11     Fields:    Translation:Humans
    546. Jacobs SC, Mason JW, Kosten TR, Wahby V, Kasl SV, Ostfeld AM. Bereavement and catecholamines. J Psychosom Res. 1986; 30(4):489-96. PMID: 3761233.
      Citations: 6     Fields:    Translation:Humans
    547. Kosten TR, Rounsaville BJ, Kleber HD. A 2.5 year follow-up of treatment retention and reentry among opioid addicts. J Subst Abuse Treat. 1986; 3(3):181-9. PMID: 3806731.
      Citations: 4     Fields:    Translation:Humans
    548. Kosten TR. Diagnosing depression with the DST and TRH in cocaine and opioid abusers. J Subst Abuse Treat. 1986; 3(1):47-9. PMID: 3090273.
      Citations: 1     Fields:    Translation:Humans
    549. Kosten TR, Gawin FH, Rounsaville BJ, Kleber HD. Abuse of cocaine with opioids: psychological aspects of treatment. NIDA Res Monogr. 1986; 67:278-82. PMID: 3092078.
      Citations:    Fields:    Translation:Humans
    550. Kosten TR, Kreek MJ, Ragunath J, Kleber HD. Chronic naltrexone effect on cortisol. NIDA Res Monogr. 1986; 67:362-5. PMID: 3092091.
      Citations: 1     Fields:    Translation:Humans
    551. Kosten TR, Hogan I, Jalali B, Steidl J, Kleber HD. The effect of multiple family therapy on addict family functioning: a pilot study. Adv Alcohol Subst Abuse. 1986; 5(3):51-62. PMID: 3728193.
      Citations:    Fields:    Translation:Humans
    552. Kosten TR, Gawin FH, Rounsaville BJ, Kleber HD. Cocaine abuse among opioid addicts: demographic and diagnostic factors in treatment. Am J Drug Alcohol Abuse. 1986; 12(1-2):1-16. PMID: 3788892.
      Citations: 18     Fields:    Translation:Humans
    553. Kosten TR, Rounsaville BJ, Kleber HD. Parental alcoholism in opioid addicts. J Nerv Ment Dis. 1985 Aug; 173(8):461-9. PMID: 4020363.
      Citations: 3     Fields:    Translation:Humans
    554. Kosten TR, Rounsaville BJ, Kleber HD. Ethnic and gender differences among opiate addicts. Int J Addict. 1985 Aug; 20(8):1143-62. PMID: 4077316.
      Citations: 25     Fields:    Translation:Humans
    555. Kleber HD, Kosten TR, Gaspari J, Topazian M. Nontolerance to the opioid antagonism of naltrexone. Biol Psychiatry. 1985 Jan; 20(1):66-72. PMID: 2981129.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    556. Kosten TR, Rounsaville BJ, Kleber HD. Comparison of clinician ratings to self reports of withdrawal during clonidine detoxification of opiate addicts. Am J Drug Alcohol Abuse. 1985; 11(1-2):1-10. PMID: 3904410.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    557. Kosten TR, Rounsaville BJ, Kleber HD. Relationship of depression to clonidine detoxification of opiate addicts. Compr Psychiatry. 1984 Sep-Oct; 25(5):503-8. PMID: 6488761.
      Citations: 3     Fields:    Translation:Humans
    558. Kosten TR, Novak P, Kleber HD. Perceived marital and family environment of opiate addicts. Am J Drug Alcohol Abuse. 1984; 10(4):491-501. PMID: 6534181.
      Citations:    Fields:    Translation:Humans
    559. Kosten TR, Kleber HD. Strategies to improve compliance with narcotic antagonists. Am J Drug Alcohol Abuse. 1984; 10(2):249-66. PMID: 6475891.
      Citations: 9     Fields:    Translation:Humans
    560. Kosten TR, Rounsaville BJ, Merikangas KR, Prusoff BA, Kleber HD. The relationship of the Maudsley Personality Inventory to depression in addicts. Compr Psychiatry. 1983 Nov-Dec; 24(6):535-42. PMID: 6653096.
      Citations:    Fields:    Translation:Humans
    561. Kosten TR, Rounsaville BJ, Kleber HD. Concurrent validity of the addiction severity index. J Nerv Ment Dis. 1983 Oct; 171(10):606-10. PMID: 6619823.
      Citations: 51     Fields:    Translation:Humans
    562. Kosten TR, Jalali B, Hogan I, Kleber HD. Family denial as a prognostic factor in opiate addict treatment outcome. J Nerv Ment Dis. 1983 Oct; 171(10):611-6. PMID: 6619824.
      Citations:    Fields:    Translation:Humans
    563. Kosten TR, Rounsaville BJ, Kleber HD. Relationship of depression to psychosocial stressors in heroin addicts. J Nerv Ment Dis. 1983 Feb; 171(2):97-104. PMID: 6822825.
      Citations: 3     Fields:    Translation:Humans
    564. Kosten TR, Rounsaville BJ, Kleber HD. DSM-III personality disorders in opiate addicts. Compr Psychiatry. 1982 Nov-Dec; 23(6):572-81. PMID: 7160176.
      Citations: 7     Fields:    Translation:Humans
    565. Kosten TR, Jalali B, Kleber HD. Complementary marital roles of male heroin addicts: evolution and intervention tactics. Am J Drug Alcohol Abuse. 1982-1983; 9(2):155-69. PMID: 7171079.
      Citations:    Fields:    Translation:Humans
    KOSTEN's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (1006)
    Explore
    _
    Co-Authors (42)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _