"Cocaine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
| Descriptor ID |
D003042
|
| MeSH Number(s) |
D02.145.074.722.388 D03.132.889.354 D03.605.084.500.722.388 D03.605.869.388
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cocaine".
Below are MeSH descriptors whose meaning is more specific than "Cocaine".
This graph shows the total number of publications written about "Cocaine" by people in this website by year, and whether "Cocaine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 6 | 0 | 6 |
| 1997 | 9 | 0 | 9 |
| 1998 | 7 | 2 | 9 |
| 1999 | 4 | 0 | 4 |
| 2000 | 2 | 1 | 3 |
| 2001 | 1 | 0 | 1 |
| 2002 | 2 | 1 | 3 |
| 2003 | 2 | 1 | 3 |
| 2005 | 6 | 2 | 8 |
| 2006 | 2 | 3 | 5 |
| 2007 | 1 | 1 | 2 |
| 2008 | 3 | 0 | 3 |
| 2009 | 3 | 0 | 3 |
| 2010 | 1 | 1 | 2 |
| 2012 | 6 | 2 | 8 |
| 2013 | 4 | 0 | 4 |
| 2014 | 5 | 4 | 9 |
| 2015 | 4 | 3 | 7 |
| 2016 | 6 | 0 | 6 |
| 2017 | 2 | 1 | 3 |
| 2018 | 3 | 0 | 3 |
| 2019 | 4 | 0 | 4 |
| 2020 | 2 | 1 | 3 |
| 2021 | 5 | 1 | 6 |
| 2022 | 6 | 1 | 7 |
| 2023 | 4 | 0 | 4 |
| 2024 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Cocaine" by people in Profiles.
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Cocaine use and head and neck cancer risk: A pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. Cancer Med. 2024 02; 13(3):e7019.
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Activity space during treatment with medication for opioid use disorder: Relationships with personality, mood, and drug use. J Subst Use Addict Treat. 2024 02; 157:209219.
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Resting-State Functional Connectivity of the Dorsal and Ventral Striatum, Impulsivity, and Severity of Use in Recently Abstinent Cocaine-Dependent Individuals. Int J Neuropsychopharmacol. 2023 09 25; 26(9):627-638.
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Use of drug purchase tasks in medications development research: orexin system regulation of cocaine and drug demand. Behav Pharmacol. 2023 08 01; 34(5):275-286.
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Promoter region variant C-824T in the TH gene modulates the subjective effects of cocaine. Am J Addict. 2023 09; 32(5):506-509.
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Naltrexone-bupropion combinations do not affect cocaine self-administration in humans. Pharmacol Biochem Behav. 2023 03; 224:173526.
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Suvorexant maintenance enhances the reinforcing but not subjective and physiological effects of intravenous cocaine in humans. Pharmacol Biochem Behav. 2022 10; 220:173466.
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Opioid-stimulant trends in overdose toxicology by race, ethnicity, & gender: An analysis in Delaware, 2013-2019. J Ethn Subst Abuse. 2024 Jul-Sep; 23(3):471-500.
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Cross-sectional examination of ultra-processed food consumption and adverse mental health symptoms. Public Health Nutr. 2022 11; 25(11):3225-3234.
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Substance Use and Performance of Toxicology Screens in the Greater Cincinnati Northern Kentucky Stroke Study. Stroke. 2022 10; 53(10):3082-3090.