"Methadone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
Descriptor ID |
D008691
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MeSH Number(s) |
D02.522.675
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Methadone".
Below are MeSH descriptors whose meaning is more specific than "Methadone".
This graph shows the total number of publications written about "Methadone" by people in this website by year, and whether "Methadone" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 3 | 0 | 3 |
1995 | 5 | 5 | 10 |
1996 | 4 | 1 | 5 |
1997 | 7 | 2 | 9 |
1998 | 4 | 4 | 8 |
1999 | 4 | 0 | 4 |
2000 | 1 | 1 | 2 |
2001 | 1 | 1 | 2 |
2002 | 1 | 1 | 2 |
2003 | 1 | 0 | 1 |
2004 | 5 | 1 | 6 |
2005 | 2 | 3 | 5 |
2006 | 2 | 0 | 2 |
2007 | 2 | 2 | 4 |
2008 | 4 | 0 | 4 |
2009 | 2 | 2 | 4 |
2010 | 1 | 3 | 4 |
2011 | 0 | 1 | 1 |
2012 | 4 | 3 | 7 |
2013 | 3 | 2 | 5 |
2014 | 3 | 1 | 4 |
2015 | 0 | 1 | 1 |
2016 | 2 | 1 | 3 |
2017 | 3 | 0 | 3 |
2018 | 4 | 1 | 5 |
2019 | 1 | 1 | 2 |
2020 | 4 | 1 | 5 |
2021 | 0 | 3 | 3 |
2022 | 0 | 2 | 2 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Methadone" by people in Profiles.
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Routine Monitoring of QTc Interval as a Barrier for Efficient Use of Methadone in Palliative Care. J Pain Symptom Manage. 2024 Feb; 67(2):e147-e150.
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The effect of a methadone-initiated memory reconsolidation updating procedure in opioid use disorder: A translational study. EBioMedicine. 2022 Nov; 85:104283.
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Opioid Weaning Protocol Using Morphine Compared With Nonprotocolized Methadone Associated With Decreased Dose and Duration of Opioid After Norwood Procedure. Pediatr Crit Care Med. 2022 05 01; 23(5):361-370.
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The OPRD1 rs678849 variant influences outcome of disulfiram treatment for cocaine dependency in methadone-maintained patients. Psychiatr Genet. 2021 06 01; 31(3):88-94.
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First-line methadone for cancer pain: titration time analysis. Support Care Cancer. 2021 Nov; 29(11):6335-6341.
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Case Report: Concurrent Clonidine Abuse and Opioid Use Disorder. J Psychoactive Drugs. 2021 Sep-Oct; 53(4):373-377.
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Switching Ratio from Parenteral to Oral Methadone 1:1.2 Is Safer Compared with Ratio 1:2 in Patients with Controlled Cancer Pain: A Multicenter Randomized-Controlled Trial (RATIOMTD-010810). J Palliat Med. 2021 03; 24(3):382-390.
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Clinically Significant Drug-Drug Interaction Between Methadone and Cannabidiol. Pediatrics. 2020 06; 145(6).
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How to Use Methadone in an Era of an Opioid Epidemic. Curr Treat Options Oncol. 2020 03 19; 21(4):30.
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Levorphanol versus methadone use: safety considerations. Ann Palliat Med. 2020 Mar; 9(2):579-585.