P-type ATPases which transport copper ions across membranes in prokaryotic and eukaryotic cells. They possess a conserved CYSTEINE-HISTIDINE-SERINE (CPx) amino acid motif within their transmembrane helices that functions in cation translocation and catalytic activation, and an N-terminal copper-binding CxxC motif that regulates enzyme activity. They play essential roles in intracellular copper homeostasis through regulating the uptake, efflux and storage of copper ions, and in cuproprotein biosynthesis.

Descriptor ID	D000073840
MeSH Number(s)	D08.811.277.040.025.314.500 D12.776.157.530.450.250.656 D12.776.157.530.813.500 D12.776.543.585.450.250.656 D12.776.543.585.813.500
Concept/Terms	Copper-transporting ATPases Copper-transporting ATPases ATPases, Copper-transporting Copper transporting ATPases Cu(+)-transporting ATPases Copper-transporting Adenosine Triphosphatases Adenosine Triphosphatases, Copper-transporting Copper transporting Adenosine Triphosphatases Triphosphatases, Copper-transporting Adenosine Copper-transporting ATPase ATPase, Copper-transporting Copper transporting ATPase Cu-transporting ATPases ATPases, Cu-transporting Cu transporting ATPases Wilson Disease Protein Wilson Disease Protein ATP7B Cu-binding P type ATPase ATP7B Cu binding P type ATPase Copper-transporting ATPase 2 Copper transporting ATPase 2 ATPase, Cu++ transporting, beta Polypeptide (Wilson Disease) Wilson Disease Cu-binding P Type ATPase Wilson Disease Cu binding P Type ATPase Copper-transporting ATPase 1 Copper-transporting ATPase 1 ATPase 1, Copper-transporting Copper transporting ATPase 1 Copper Pump 1 Menkes Disease-associated Protein Menkes Disease associated Protein ATP7A Protein ATPase Copper Transporting alpha Pineal Night-specific ATPase Pineal Night-specific ATPase ATPase, Pineal Night-specific Night-specific ATPase, Pineal Pineal Night specific ATPase PINA Enzyme

Below are MeSH descriptors whose meaning is more general than "Copper-transporting ATPases".

Below are MeSH descriptors whose meaning is related to "Copper-transporting ATPases".

Below are MeSH descriptors whose meaning is more specific than "Copper-transporting ATPases".