Receptors, Cytoplasmic and Nuclear
"Receptors, Cytoplasmic and Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.
Descriptor ID |
D018160
|
MeSH Number(s) |
D12.776.826
|
Concept/Terms |
Receptors, Cytoplasmic and Nuclear- Receptors, Cytoplasmic and Nuclear
- Receptors, Cytosol and Nuclear
- Cytosolic and Nuclear Receptors
- Receptors, Nuclear and Cytoplasmic
- Cytoplasmic and Nuclear Receptors
- Cytosol and Nuclear Receptors
- Nuclear and Cytoplasmic Receptors
- Receptors, Cytosolic and Nuclear
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Cytoplasmic and Nuclear".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Cytoplasmic and Nuclear".
This graph shows the total number of publications written about "Receptors, Cytoplasmic and Nuclear" by people in this website by year, and whether "Receptors, Cytoplasmic and Nuclear" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 4 | 0 | 4 |
1995 | 1 | 0 | 1 |
1996 | 1 | 2 | 3 |
1997 | 6 | 2 | 8 |
1998 | 6 | 1 | 7 |
1999 | 10 | 7 | 17 |
2000 | 7 | 9 | 16 |
2001 | 12 | 3 | 15 |
2002 | 12 | 5 | 17 |
2003 | 20 | 7 | 27 |
2004 | 14 | 15 | 29 |
2005 | 19 | 10 | 29 |
2006 | 14 | 8 | 22 |
2007 | 14 | 2 | 16 |
2008 | 6 | 3 | 9 |
2009 | 10 | 3 | 13 |
2010 | 10 | 6 | 16 |
2011 | 9 | 5 | 14 |
2012 | 9 | 1 | 10 |
2013 | 8 | 6 | 14 |
2014 | 8 | 6 | 14 |
2015 | 12 | 3 | 15 |
2016 | 9 | 3 | 12 |
2017 | 10 | 2 | 12 |
2018 | 5 | 3 | 8 |
2019 | 6 | 3 | 9 |
2020 | 5 | 2 | 7 |
2021 | 4 | 2 | 6 |
2022 | 1 | 5 | 6 |
2023 | 0 | 3 | 3 |
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Below are the most recent publications written about "Receptors, Cytoplasmic and Nuclear" by people in Profiles.
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Therapeutic implications of impaired nuclear receptor function and dysregulated metabolism in Wilson's disease. Pharmacol Ther. 2023 Nov; 251:108529.
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International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023. Pharmacol Rev. 2023 Nov; 75(6):1233-1318.
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A novel de novo pathogenic variant in TBL1XR1 as a new proposed cause of Pierpont syndrome. Am J Med Genet A. 2023 06; 191(6):1576-1580.
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Exportin(g) precision oncology beyond genomics with XPO1 inhibition. Med. 2022 11 11; 3(11):730-732.
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Loss of heat shock factor initiates intracellular lipid surveillance by actin destabilization. Cell Rep. 2022 10 18; 41(3):111493.
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Maternal and Fetal Bile Acid Homeostasis Regulated by Sulfated Progesterone Metabolites through FXR Signaling Pathway in a Pregnant Sow Model. Int J Mol Sci. 2022 Jun 10; 23(12).
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Intracellular lipid surveillance by small G protein geranylgeranylation. Nature. 2022 05; 605(7911):736-740.
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Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis. Proc Natl Acad Sci U S A. 2022 03 29; 119(13):e2023784119.
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Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML. Cell Rep. 2022 03 08; 38(10):110481.
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Tissue-specific mechanisms of bile acid homeostasis and activation of FXR-FGF19 signaling in preterm and term neonatal pigs. Am J Physiol Gastrointest Liver Physiol. 2022 01 01; 322(1):G117-G133.