Receptors, Cytoplasmic and Nuclear
"Receptors, Cytoplasmic and Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.
| Descriptor ID |
D018160
|
| MeSH Number(s) |
D12.776.826
|
| Concept/Terms |
Receptors, Cytoplasmic and Nuclear- Receptors, Cytoplasmic and Nuclear
- Receptors, Cytosol and Nuclear
- Cytosolic and Nuclear Receptors
- Receptors, Nuclear and Cytoplasmic
- Cytoplasmic and Nuclear Receptors
- Cytosol and Nuclear Receptors
- Nuclear and Cytoplasmic Receptors
- Receptors, Cytosolic and Nuclear
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Cytoplasmic and Nuclear".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Cytoplasmic and Nuclear".
This graph shows the total number of publications written about "Receptors, Cytoplasmic and Nuclear" by people in this website by year, and whether "Receptors, Cytoplasmic and Nuclear" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 2 | 3 |
| 1997 | 4 | 2 | 6 |
| 1998 | 3 | 0 | 3 |
| 1999 | 9 | 1 | 10 |
| 2000 | 5 | 5 | 10 |
| 2001 | 7 | 2 | 9 |
| 2002 | 8 | 3 | 11 |
| 2003 | 11 | 3 | 14 |
| 2004 | 6 | 5 | 11 |
| 2005 | 7 | 7 | 14 |
| 2006 | 7 | 3 | 10 |
| 2007 | 10 | 2 | 12 |
| 2008 | 4 | 3 | 7 |
| 2009 | 6 | 1 | 7 |
| 2010 | 9 | 2 | 11 |
| 2011 | 5 | 1 | 6 |
| 2012 | 7 | 1 | 8 |
| 2013 | 6 | 4 | 10 |
| 2014 | 4 | 6 | 10 |
| 2015 | 7 | 2 | 9 |
| 2016 | 7 | 1 | 8 |
| 2017 | 8 | 0 | 8 |
| 2018 | 5 | 3 | 8 |
| 2019 | 3 | 3 | 6 |
| 2020 | 4 | 2 | 6 |
| 2021 | 3 | 1 | 4 |
| 2022 | 1 | 4 | 5 |
| 2023 | 0 | 3 | 3 |
| 2025 | 4 | 2 | 6 |
| 2026 | 1 | 1 | 2 |
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Below are the most recent publications written about "Receptors, Cytoplasmic and Nuclear" by people in Profiles.
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Stomach at the crossroads: nuclear receptor signaling at the interface between what we are and what we eat. Physiol Rev. 2026 07 01; 106(3):1495-1533.
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Silencing lipid catabolism determines longevity in response to fasting. Nat Commun. 2026 Jan 22; 17(1).
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Selective agonism of liver and gut FXR prevents cholestasis and intestinal atrophy in parenterally fed neonatal pigs. J Lipid Res. 2025 Nov; 66(11):100919.
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Pathogenic XPO1 variants cause a dominant neurodevelopmental disorder. Genet Med. 2025 Nov; 27(11):101555.
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The potential of 4-Methylumbelliferone to be repurposed for treating liver fibrosis. Biomed Pharmacother. 2025 Sep; 190:118427.
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Muscle Rev-erb controls time-dependent adaptations to chronic exercise in mice. Nat Commun. 2025 Jul 01; 16(1):5708.
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Changes in the FXR-cistrome and alterations in bile acid physiology in Wilson disease. Hepatol Commun. 2025 Jun 01; 9(6).
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Bile acid regulation of xenobiotic nuclear receptors on the expressions of orosomucoids in the liver. Am J Physiol Endocrinol Metab. 2025 06 01; 328(6):E940-E951.
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Therapeutic implications of impaired nuclear receptor function and dysregulated metabolism in Wilson's disease. Pharmacol Ther. 2023 11; 251:108529.
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International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023. Pharmacol Rev. 2023 11; 75(6):1233-1318.