CRISPR-Associated Proteins
"CRISPR-Associated Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein components of the CRISPR-CAS SYSTEMS for anti-viral defense in ARCHAEA and BACTERIA. These are proteins that carry out a variety of functions during the creation and expansion of the CRISPR ARRAYS, the capture of new CRISPR SPACERS, biogenesis of SMALL INTERFERING RNA (CRISPR or crRNAs), and the targeting and silencing of invading viruses and plasmids. They include DNA HELICASES; RNA-BINDING PROTEINS; ENDONUCLEASES; and RNA and DNA POLYMERASES.
| Descriptor ID |
D064130
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| MeSH Number(s) |
D12.776.212
|
| Concept/Terms |
CRISPR-Associated Protein Complex Proteins- CRISPR-Associated Protein Complex Proteins
- CRISPR Associated Protein Complex Proteins
- CRISPR-Associated Complex for Antiviral Defense Proteins
- CRISPR Associated Complex for Antiviral Defense Proteins
- CASCADE Proteins, CRISPR-Associated
- CASCADE Proteins, CRISPR Associated
- CRISPR-Associated CASCADE Proteins
|
Below are MeSH descriptors whose meaning is more general than "CRISPR-Associated Proteins".
Below are MeSH descriptors whose meaning is more specific than "CRISPR-Associated Proteins".
This graph shows the total number of publications written about "CRISPR-Associated Proteins" by people in this website by year, and whether "CRISPR-Associated Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 2 | 1 | 3 |
| 2018 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "CRISPR-Associated Proteins" by people in Profiles.
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A One-Step RPA-CRISPR Assay Using crRNA Based on Suboptimal Protospacer Adjacent Motif for Vibrio vulnificus Detection. Foodborne Pathog Dis. 2024 Jul; 21(7):458-466.
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Repurposing type I-F CRISPR-Cas system as a transcriptional activation tool in human cells. Nat Commun. 2020 06 19; 11(1):3136.
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Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry. Cell Res. 2019 04; 29(4):305-312.
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Genome-wide profiling of adenine base editor specificity by EndoV-seq. Nat Commun. 2019 01 08; 10(1):67.
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A Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition. Mol Cell. 2018 11 15; 72(4):700-714.e8.
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The Implications of CRISPR-Cas9 Genome Editing for IR. J Vasc Interv Radiol. 2018 09; 29(9):1264-1267.e1.
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CCR5 gene disruption via lentiviral vectors expressing Cas9 and single guided RNA renders cells resistant to HIV-1 infection. PLoS One. 2014; 9(12):e115987.
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Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers. Biochem J. 2014 Sep 15; 462(3):397-413.
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Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes. Dev Biol. 2014 Sep 01; 393(1):3-9.
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CRISPR/Cas9-based genome editing in mice by single plasmid injection. Methods Enzymol. 2014; 546:319-36.