"Protein Isoforms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE SPLICING.
| Descriptor ID |
D020033
|
| MeSH Number(s) |
D12.776.800
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Isoforms".
Below are MeSH descriptors whose meaning is more specific than "Protein Isoforms".
This graph shows the total number of publications written about "Protein Isoforms" by people in this website by year, and whether "Protein Isoforms" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 8 | 8 |
| 2000 | 2 | 14 | 16 |
| 2001 | 0 | 14 | 14 |
| 2002 | 0 | 13 | 13 |
| 2003 | 1 | 15 | 16 |
| 2004 | 0 | 20 | 20 |
| 2005 | 0 | 13 | 13 |
| 2006 | 0 | 6 | 6 |
| 2007 | 0 | 11 | 11 |
| 2008 | 4 | 13 | 17 |
| 2009 | 2 | 15 | 17 |
| 2010 | 0 | 16 | 16 |
| 2011 | 2 | 8 | 10 |
| 2012 | 0 | 12 | 12 |
| 2013 | 1 | 8 | 9 |
| 2014 | 3 | 13 | 16 |
| 2015 | 0 | 6 | 6 |
| 2016 | 2 | 10 | 12 |
| 2017 | 0 | 19 | 19 |
| 2018 | 1 | 14 | 15 |
| 2019 | 0 | 7 | 7 |
| 2020 | 0 | 6 | 6 |
| 2021 | 2 | 4 | 6 |
| 2022 | 0 | 10 | 10 |
| 2023 | 0 | 9 | 9 |
| 2024 | 0 | 3 | 3 |
| 2025 | 0 | 7 | 7 |
| 2026 | 0 | 2 | 2 |
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Below are the most recent publications written about "Protein Isoforms" by people in Profiles.
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Identification of CAND1 as a DNA-dependent protein kinase-regulated coactivator of androgen receptor and the ARv7 splice variant. PLoS One. 2026; 21(5):e0349130.
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Modulating alternative splicing of MECP2 is a potential therapeutic strategy for Rett syndrome. Sci Transl Med. 2026 Mar 04; 18(839):eadq4529.
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Therapeutic p63 isoform switching rescues epidermal defects in AEC syndrome. Mol Ther. 2026 Apr 01; 34(4):2324-2342.
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A clinical and genotype-phenotype analysis of MACF1 variants. Am J Hum Genet. 2025 Oct 02; 112(10):2363-2380.
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Divergent Roles of C/EBP? Isoforms LAP and LIP in Shaping T Cell Dysfunction and Tumor Progression in Triple-Negative Breast Cancer. FASEB J. 2025 Aug 31; 39(16):e70984.
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Progesterone receptor isoform modulation via enhancer activation regulates progesterone signaling in endometrial stromal cells. F S Sci. 2025 Nov; 6(4):397-413.
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Integrated proteomics identifies troponin I isoform switch as a regulator of a sarcomere-metabolism axis during cardiac regeneration. Cardiovasc Res. 2025 Jul 31; 121(8):1240-1253.
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Structural proteomics defines a sequential priming mechanism for the progesterone receptor. Nat Commun. 2025 May 12; 16(1):4403.
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Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms. Mol Cell. 2025 Apr 03; 85(7):1445-1466.e13.
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Non-coding cause of congenital heart defects: Abnormal RNA splicing with multiple isoforms as a mechanism for heterotaxy. HGG Adv. 2024 Oct 10; 5(4):100353.