"Protein Isoforms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE SPLICING.
| Descriptor ID |
D020033
|
| MeSH Number(s) |
D12.776.800
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Isoforms".
Below are MeSH descriptors whose meaning is more specific than "Protein Isoforms".
This graph shows the total number of publications written about "Protein Isoforms" by people in this website by year, and whether "Protein Isoforms" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 8 | 8 |
| 2000 | 2 | 15 | 17 |
| 2001 | 0 | 17 | 17 |
| 2002 | 0 | 13 | 13 |
| 2003 | 1 | 16 | 17 |
| 2004 | 0 | 22 | 22 |
| 2005 | 0 | 14 | 14 |
| 2006 | 0 | 6 | 6 |
| 2007 | 0 | 12 | 12 |
| 2008 | 4 | 13 | 17 |
| 2009 | 2 | 14 | 16 |
| 2010 | 0 | 15 | 15 |
| 2011 | 2 | 7 | 9 |
| 2012 | 0 | 13 | 13 |
| 2013 | 1 | 9 | 10 |
| 2014 | 3 | 13 | 16 |
| 2015 | 0 | 5 | 5 |
| 2016 | 3 | 10 | 13 |
| 2017 | 0 | 21 | 21 |
| 2018 | 1 | 13 | 14 |
| 2019 | 0 | 8 | 8 |
| 2020 | 0 | 6 | 6 |
| 2021 | 2 | 6 | 8 |
| 2022 | 1 | 11 | 12 |
| 2023 | 0 | 9 | 9 |
| 2024 | 0 | 3 | 3 |
| 2025 | 0 | 5 | 5 |
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Below are the most recent publications written about "Protein Isoforms" by people in Profiles.
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A clinical and genotype-phenotype analysis of MACF1 variants. Am J Hum Genet. 2025 Oct 02; 112(10):2363-2380.
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Divergent Roles of C/EBP? Isoforms LAP and LIP in Shaping T Cell Dysfunction and Tumor Progression in Triple-Negative Breast Cancer. FASEB J. 2025 Aug 31; 39(16):e70984.
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Integrated proteomics identifies troponin I isoform switch as a regulator of a sarcomere-metabolism axis during cardiac regeneration. Cardiovasc Res. 2025 Jul 31; 121(8):1240-1253.
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Structural proteomics defines a sequential priming mechanism for the progesterone receptor. Nat Commun. 2025 May 12; 16(1):4403.
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Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms. Mol Cell. 2025 Apr 03; 85(7):1445-1466.e13.
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Non-coding cause of congenital heart defects: Abnormal RNA splicing with multiple isoforms as a mechanism for heterotaxy. HGG Adv. 2024 Oct 10; 5(4):100353.
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Global prevalence of claudin 18 isoform 2 in tumors of patients with locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma. Gastric Cancer. 2024 Sep; 27(5):1058-1068.
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A method for rapid and reliable quantification of VEGF-cell binding activity. Biochem Biophys Res Commun. 2024 10 01; 727:150321.
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Retrospective Study of Claudin 18 Isoform 2 Prevalence and Prognostic Association in Gastric and Gastroesophageal Junction Adenocarcinoma. JCO Precis Oncol. 2024 May; 8:e2300543.
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Identification of Nonfunctional Alternatively Spliced Isoforms of STING in Human Acute Myeloid Leukemia. Cancer Res Commun. 2024 03 25; 4(3):911-918.