"Cystatins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A homologous group of endogenous CYSTEINE PROTEINASE INHIBITORS. The cystatins inhibit most CYSTEINE ENDOPEPTIDASES such as PAPAIN, and other peptidases which have a sulfhydryl group at the active site.
| Descriptor ID |
D015891
|
| MeSH Number(s) |
D12.776.215
|
| Concept/Terms |
Type 3 Cystatins- Type 3 Cystatins
- Cystatins, Type 3
- Type III Cystatins
- Cystatins, Type III
Type 2 Cystatins- Type 2 Cystatins
- Cystatins, Type 2
- Type II Cystatins
- Cystatins, Type II
Type 1 Cystatins- Type 1 Cystatins
- Cystatins, Type 1
- Type I Cystatins
- Cystatins, Type I
- Stefins
|
Below are MeSH descriptors whose meaning is more general than "Cystatins".
Below are MeSH descriptors whose meaning is more specific than "Cystatins".
This graph shows the total number of publications written about "Cystatins" by people in this website by year, and whether "Cystatins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cystatins" by people in Profiles.
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Schistosoma japonicum cystatin alleviates paraquat poisoning caused acute lung injury in mice through activating regulatory macrophages. Ecotoxicol Environ Saf. 2024 Aug; 281:116615.
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Trichinella spiralis cystatin alleviates polymicrobial sepsis through activating regulatory macrophages. Int Immunopharmacol. 2022 Aug; 109:108907.
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Schistosoma japonicum Cystatin Alleviates Sepsis Through Activating Regulatory Macrophages. Front Cell Infect Microbiol. 2021; 11:617461.
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Therapeutic efficacy of Schistosoma japonicum cystatin on sepsis-induced cardiomyopathy in a mouse model. Parasit Vectors. 2020 May 18; 13(1):260.
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Therapeutic effect of Schistosoma japonicum cystatin on bacterial sepsis in mice. Parasit Vectors. 2017 May 08; 10(1):222.
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Renal impairment and outcomes in heart failure: systematic review and meta-analysis. J Am Coll Cardiol. 2006 May 16; 47(10):1987-96.
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Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors. J Biol Chem. 2006 Mar 03; 281(9):6020-9.
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Apoptosis caused by cathepsins does not require Bid signaling in an in vivo model of progressive myoclonus epilepsy (EPM1). Cell Death Differ. 2003 Dec; 10(12):1329-35.
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Progressive ataxia, myoclonic epilepsy and cerebellar apoptosis in cystatin B-deficient mice. Nat Genet. 1998 Nov; 20(3):251-8.
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Role of the occluding loop in cathepsin B activity. J Biol Chem. 1997 Jan 10; 272(2):1197-202.