Proteinase Inhibitory Proteins, Secretory
"Proteinase Inhibitory Proteins, Secretory" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptides and proteins found in BODILY SECRETIONS and BODY FLUIDS that are PROTEASE INHIBITORS. They play a role in INFLAMMATION, tissue repair and innate immunity (IMMUNITY, INNATE) by inhibiting endogenous proteinases such as those produced by LEUKOCYTES and exogenous proteases such as those produced by invading microorganisms.
| Descriptor ID |
D053491
|
| MeSH Number(s) |
D12.644.822 D12.776.645
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Proteinase Inhibitory Proteins, Secretory".
Below are MeSH descriptors whose meaning is more specific than "Proteinase Inhibitory Proteins, Secretory".
This graph shows the total number of publications written about "Proteinase Inhibitory Proteins, Secretory" by people in this website by year, and whether "Proteinase Inhibitory Proteins, Secretory" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Proteinase Inhibitory Proteins, Secretory" by people in Profiles.
-
The fibroblast-derived protein PI16 controls neuropathic pain. Proc Natl Acad Sci U S A. 2020 03 10; 117(10):5463-5471.
-
Imbalanced matriptase pericellular proteolysis contributes to the pathogenesis of malignant B-cell lymphomas. Am J Pathol. 2013 Oct; 183(4):1306-17.
-
Inhibition of human kallikreins 5 and 7 by the serine protease inhibitor lympho-epithelial Kazal-type inhibitor (LEKTI). Biol Chem. 2005 Nov; 386(11):1173-84.
-
Negative regulation of two hyperproliferative keratinocyte differentiation markers by a retinoic acid receptor-specific retinoid: insight into the mechanism of retinoid action in psoriasis. Cell Growth Differ. 1996 Dec; 7(12):1783-91.