"Polyglutamic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide that is a homopolymer of glutamic acid.
| Descriptor ID |
D011099
|
| MeSH Number(s) |
D12.125.067.625.700 D12.125.119.409.700 D12.644.748
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Polyglutamic Acid".
Below are MeSH descriptors whose meaning is more specific than "Polyglutamic Acid".
This graph shows the total number of publications written about "Polyglutamic Acid" by people in this website by year, and whether "Polyglutamic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 3 | 0 | 3 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 2 | 2 | 4 |
| 2001 | 1 | 0 | 1 |
| 2002 | 2 | 0 | 2 |
| 2003 | 2 | 0 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 7 | 1 | 8 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Polyglutamic Acid" by people in Profiles.
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Methotrexate accumulation in target intestinal mucosa and white blood cells differs from non-target red blood cells of patients with Crohn's disease. Basic Clin Pharmacol Toxicol. 2024 Sep; 135(3):308-320.
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[Preparation and properties of paclitaxel-loaded self-assembling nano-micelles of cholesterol-bearing ?-Polyglutamic acid]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2018 06 25; 35(3):403-408.
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Phase Ib/II Trial of NC-6004 (Nanoparticle Cisplatin) Plus Gemcitabine in Patients with Advanced Solid Tumors. Clin Cancer Res. 2018 01 01; 24(1):43-51.
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A hindsight reflection on the clinical studies of poly(l-glutamic acid)-paclitaxel. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2018 05; 10(3):e1497.
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An injectable nanoparticle generator enhances delivery of cancer therapeutics. Nat Biotechnol. 2016 Apr; 34(4):414-8.
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Multifunctional synthetic poly(L-glutamic acid)-based cancer therapeutic and imaging agents. Mol Imaging. 2011 Feb; 10(1):28-42.
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Pharmacokinetics and magnetic resonance imaging of biodegradable macromolecular blood-pool contrast agent PG-Gd in non-human primates: a pilot study. Contrast Media Mol Imaging. 2011 Jul-Aug; 6(4):289-97.
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Targeted imaging of tumor-associated M2 macrophages using a macromolecular contrast agent PG-Gd-NIR813. Biomaterials. 2010 Sep; 31(25):6567-73.
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Polymer-drug conjugates: recent development in clinical oncology. Adv Drug Deliv Rev. 2008 May 22; 60(8):886-98.
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Micelles based on biodegradable poly(L-glutamic acid)-b-polylactide with paramagnetic Gd ions chelated to the shell layer as a potential nanoscale MRI-visible delivery system. Biomacromolecules. 2008 Jan; 9(1):36-42.