"Polyglutamic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide that is a homopolymer of glutamic acid.
| Descriptor ID |
D011099
|
| MeSH Number(s) |
D12.125.067.625.700 D12.125.119.409.700 D12.644.748
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Polyglutamic Acid".
Below are MeSH descriptors whose meaning is more specific than "Polyglutamic Acid".
This graph shows the total number of publications written about "Polyglutamic Acid" by people in this website by year, and whether "Polyglutamic Acid" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Polyglutamic Acid" by people in Profiles.
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Multifunctional synthetic poly(L-glutamic acid)-based cancer therapeutic and imaging agents. Mol Imaging. 2011 Feb; 10(1):28-42.
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Pharmacokinetics and magnetic resonance imaging of biodegradable macromolecular blood-pool contrast agent PG-Gd in non-human primates: a pilot study. Contrast Media Mol Imaging. 2011 Jul-Aug; 6(4):289-97.
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Polymer-drug conjugates: recent development in clinical oncology. Adv Drug Deliv Rev. 2008 May 22; 60(8):886-98.
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Micelles based on biodegradable poly(L-glutamic acid)-b-polylactide with paramagnetic Gd ions chelated to the shell layer as a potential nanoscale MRI-visible delivery system. Biomacromolecules. 2008 Jan; 9(1):36-42.
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Phase I trial of poly-L-glutamate camptothecin (CT-2106) administered weekly in patients with advanced solid malignancies. Clin Cancer Res. 2007 Oct 01; 13(19):5855-61.
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Antitumor activity of 4-(N-hydroxyphenyl)retinamide conjugated with poly(L-glutamic acid) against ovarian cancer xenografts. Gynecol Oncol. 2007 Dec; 107(3):441-9.
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Polymeric retinoid prodrug PG-4HPR enhances the radiation response of lung cancer. Oncol Rep. 2007 Sep; 18(3):645-51.
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Development of a macromolecular dual-modality MR-optical imaging for sentinel lymph node mapping. Invest Radiol. 2007 Aug; 42(8):569-78.
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Magnetic resonance imaging of therapy-induced necrosis using gadolinium-chelated polyglutamic acids. Int J Radiat Oncol Biol Phys. 2007 Jul 01; 68(3):830-8.
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A novel method for imaging in vivo degradation of poly(L-glutamic acid), a biodegradable drug carrier. Pharm Res. 2007 Jun; 24(6):1217-24.