"Peptoids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Polymers of N-SUBSTITUTED GLYCINES containing chiral centers at the a-position of their side chains. These oligomers lack HYDROGEN BONDING donors, preventing formation of the usual intrachain hydrogen bonds but can form helices driven by the steric influence of chiral side chains.
| Descriptor ID |
D034444
|
| MeSH Number(s) |
D12.644.679
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Peptoids".
Below are MeSH descriptors whose meaning is more specific than "Peptoids".
This graph shows the total number of publications written about "Peptoids" by people in this website by year, and whether "Peptoids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 2 | 0 | 2 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Peptoids" by people in Profiles.
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Linker optimization and activity validation of a cell surface vimentin targeted homo-dimeric peptoid antagonist for lung cancer stem cells. Bioorg Med Chem. 2024 01 01; 97:117560.
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Optimization of a cell surface vimentin binding peptoid to extract antagonist effect on lung cancer cells. Bioorg Chem. 2022 Dec; 129:106113.
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Unbiased peptoid cell screen identifies a peptoid targeting newly appeared cell surface vimentin on tumor transformed early lung cancer cells. Bioorg Med Chem. 2022 03 15; 58:116673.
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"Molecular Masks" for ACE2 to Effectively and Safely Block SARS-CoV-2 Virus Entry. Int J Mol Sci. 2021 Aug 20; 22(16).
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Unbiased peptoid combinatorial cell screen identifies plectin protein as a potential biomarker for lung cancer stem cells. Sci Rep. 2019 10 18; 9(1):14954.
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A comprehensive lipid binding and activity validation of a cancer-specific peptide-peptoid hybrid PPS1. Biochem Biophys Res Commun. 2017 04 29; 486(2):545-550.
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Development of a large peptoid-DOTA combinatorial library. Biopolymers. 2016 Sep; 106(5):673-84.
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Identification of the minimum pharmacophore of lipid-phosphatidylserine (PS) binding peptide-peptoid hybrid PPS1D1. Bioorg Med Chem. 2016 09 15; 24(18):4470-4477.
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Improving biomarker identification with better designs and reporting. Clin Chem. 2011 Aug; 57(8):1093-5.
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GU81, a VEGFR2 antagonist peptoid, enhances the anti-tumor activity of doxorubicin in the murine MMTV-PyMT transgenic model of breast cancer. BMC Cancer. 2010 Jul 30; 10:397.