Sodium Potassium Chloride Symporter Inhibitors
"Sodium Potassium Chloride Symporter Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA.
| Descriptor ID |
D049994
|
| MeSH Number(s) |
D27.505.519.562.906 D27.505.696.560.500.931
|
| Concept/Terms |
Sodium Potassium Chloride Symporter Inhibitors- Sodium Potassium Chloride Symporter Inhibitors
- Na-K-CL Symporter Inhibitors
- Inhibitors, Na-K-CL Symporter
- Na K CL Symporter Inhibitors
- Symporter Inhibitors, Na-K-CL
- Sodium Potassium Chloride Cotransporter Inhibitors
- Bumetanide Sensitive Na-K-Cl-Transporter Inhibitors
- Bumetanide Sensitive Na K Cl Transporter Inhibitors
|
Below are MeSH descriptors whose meaning is more general than "Sodium Potassium Chloride Symporter Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Sodium Potassium Chloride Symporter Inhibitors".
This graph shows the total number of publications written about "Sodium Potassium Chloride Symporter Inhibitors" by people in this website by year, and whether "Sodium Potassium Chloride Symporter Inhibitors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 2 | 3 |
| 2017 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Sodium Potassium Chloride Symporter Inhibitors" by people in Profiles.
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Relation of Low Chloride Concentration to Diuretic Efficiency and Transplant-Free Survival in Children Hospitalized With Heart Failure. Am J Cardiol. 2022 12 01; 184:72-79.
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Revisiting diuretic choice in chronic kidney disease. Curr Opin Nephrol Hypertens. 2022 09 01; 31(5):406-413.
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Tubular Acidification Defect in Adults with Sickle Cell Disease. Clin J Am Soc Nephrol. 2020 01 07; 15(1):16-24.
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Diuretic Responsiveness and Its Prognostic Significance in Children With Heart Failure. J Card Fail. 2019 Dec; 25(12):941-947.
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Expert Panel Recommendations for the Identification and Management of Hyperkalemia and Role of Patiromer in Patients with Chronic Kidney Disease and Heart Failure. J Manag Care Spec Pharm. 2017 Apr; 23(4-a Suppl):S10-S19.
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NKCC1 up-regulation contributes to early post-traumatic seizures and increased post-traumatic seizure susceptibility. Brain Struct Funct. 2017 04; 222(3):1543-1556.
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Efficacy of loop diuretics in the management of undocumented patients with end-stage renal disease. Am J Emerg Med. 2016 Aug; 34(8):1552-5.
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Chronic Unpredictable Mild Stress Induces Loss of GABA Inhibition in Corticotrophin-Releasing Hormone-Expressing Neurons through NKCC1 Upregulation. Neuroendocrinology. 2017; 104(2):194-208.
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Comment on "is addition of vasodilators to loop diuretics of value in the care of hospitalized acute heart failure patients? Real-world evidence from a retrospective analysis of a large United States hospital database". J Card Fail. 2015 May; 21(5):434-435.
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With-No-Lysine Kinase 3 (WNK3) stimulates glioma invasion by regulating cell volume. Am J Physiol Cell Physiol. 2011 Nov; 301(5):C1150-60.