"Troponin I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
| Descriptor ID |
D019210
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| MeSH Number(s) |
D05.500.945.925 D05.750.078.730.825.925 D12.776.210.500.910.925 D12.776.220.525.825.925
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Troponin I".
Below are MeSH descriptors whose meaning is more specific than "Troponin I".
This graph shows the total number of publications written about "Troponin I" by people in this website by year, and whether "Troponin I" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 2 | 3 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 1 | 2 |
| 2002 | 1 | 0 | 1 |
| 2003 | 3 | 0 | 3 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 2 | 1 | 3 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 3 | 4 |
| 2014 | 4 | 1 | 5 |
| 2015 | 2 | 1 | 3 |
| 2016 | 5 | 0 | 5 |
| 2017 | 3 | 1 | 4 |
| 2018 | 4 | 1 | 5 |
| 2019 | 4 | 3 | 7 |
| 2020 | 11 | 2 | 13 |
| 2021 | 3 | 5 | 8 |
| 2022 | 0 | 4 | 4 |
| 2023 | 0 | 3 | 3 |
| 2024 | 3 | 2 | 5 |
| 2025 | 4 | 0 | 4 |
| 2026 | 1 | 1 | 2 |
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Below are the most recent publications written about "Troponin I" by people in Profiles.
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Prediabetes, Subclinical Myocardial Injury or Stress, and Heart Failure Risk for Adults With Hypertension. JAMA Cardiol. 2026 Mar 01; 11(3):281-287.
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Ultrasound-enabled refreshable electrochemical sensors for cardiac biomarker monitoring. Biosens Bioelectron. 2026 Jun 15; 302:118519.
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N-Terminal Pro-B-Type Natriuretic Peptide and B-Type Natriuretic Peptide-to-Troponin - Ratios for Differentiating Type 1 From Type 2 Myocardial Infarction: A HIGH-US Substudy. Crit Pathw Cardiol. 2025 Dec 01; 24(4):e0399.
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Integrated proteomics identifies troponin I isoform switch as a regulator of a sarcomere-metabolism axis during cardiac regeneration. Cardiovasc Res. 2025 Jul 31; 121(8):1240-1253.
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Elevated Troponin in an Infant With Spinal Muscular Atrophy. J Child Neurol. 2026 Jan; 41(1):105-108.
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A Meta-Analysis and Systematic Review of Cardiac Troponin I vs T in Community Dwelling Adults: Is Specificity at Risk? Clin Chem. 2025 Jun 03; 71(6):664-676.
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NT-proBNP and Cardiac Troponin I, but Not Cardiac Troponin T, Are Associated With 7-Year Changes in Cardiac Structure and Function in Older Adults: The ARIC Study. Circulation. 2024 Dec 03; 150(23):1847-1857.
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Protocol for Improving Care by FAster risk-STratification through use of high sensitivity point-of-care troponin in patients presenting with possible acute coronary syndrome in the EmeRgency department (ICare-FASTER): a stepped-wedge cluster randomised quality improvement initiative. BMJ Open. 2024 06 13; 14(6):e083752.
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Prognostic Value of Cardiovascular Biomarkers in the Population. JAMA. 2024 06 11; 331(22):1898-1909.
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Individual and Joint Associations of High-Sensitivity Troponin I and High-Sensitivity Troponin T with Cardiac Phenotypes and Outcomes in the General Population: An Analysis From the Dallas Heart Study. J Am Heart Assoc. 2024 Jul 02; 13(13):e034549.