"Calcium Channel Agonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in VASCULAR SMOOTH MUSCLE and/or CARDIAC MUSCLE cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture.
| Descriptor ID |
D002120
|
| MeSH Number(s) |
D27.505.519.562.124 D27.505.954.411.793.205
|
| Concept/Terms |
Calcium Channel Agonists- Calcium Channel Agonists
- Agonists, Calcium Channel
- Channel Agonists, Calcium
- Calcium Channel Activators
- Activators, Calcium Channel
- Channel Activators, Calcium
- Calcium Channel Agonist
- Agonist, Calcium Channel
- Channel Agonist, Calcium
|
Below are MeSH descriptors whose meaning is more general than "Calcium Channel Agonists".
Below are MeSH descriptors whose meaning is more specific than "Calcium Channel Agonists".
This graph shows the total number of publications written about "Calcium Channel Agonists" by people in this website by year, and whether "Calcium Channel Agonists" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 2 | 3 |
| 2007 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Calcium Channel Agonists" by people in Profiles.
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The Ryanodine Receptor Contributes to the Lysophosphatidylcholine-Induced Mineralization in Valvular Interstitial Cells. Cardiovasc Eng Technol. 2020 06; 11(3):316-327.
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Disruption of K(2P)6.1 produces vascular dysfunction and hypertension in mice. Hypertension. 2011 Oct; 58(4):672-8.
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Activation of cholinergic receptors blocks non-adrenergic non-cholinergic contractions in the rat urinary bladder. Brain Res Bull. 2008 Dec 16; 77(6):420-6.
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Ryanodine receptors as pharmacological targets for heart disease. Acta Pharmacol Sin. 2007 Jul; 28(7):937-44.
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A role for L-type calcium channels in the maturation of parvalbumin-containing hippocampal interneurons. Neuroscience. 2005; 135(3):839-50.
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Androgen receptor signaling and vitamin D receptor action in prostate cancer cells. Prostate. 2005 Sep 01; 64(4):362-72.
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Role of insulin-like growth factor binding proteins in 1alpha,25-dihydroxyvitamin D(3)-induced growth inhibition of human prostate cancer cells. Prostate. 2005 Jun 15; 64(1):9-19.
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Facilitation of L-type Ca2+ channels in dendritic spines by activation of beta2 adrenergic receptors. J Neurosci. 2004 Sep 29; 24(39):8416-27.
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1alpha,25-dihydroxyvitamin D3 induced growth inhibition of PC-3 prostate cancer cells requires an active transforming growth factor beta signaling pathway. Prostate. 2004 May 15; 59(3):282-91.
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The nephrologist's role in the management of calcium-phosphorus metabolism in patients with chronic kidney disease. Kidney Int. 2003 May; 63(5):1836-42.