"MAP Kinase Kinase 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitogen-activated protein kinase kinase with specificity for MITOGEN-ACTIVATED PROTEIN KINASE 7.
| Descriptor ID |
D048671
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.565.500 D08.811.913.696.620.682.725.200.500 D12.644.360.440.500 D12.776.476.440.500
|
| Concept/Terms |
MAP Kinase Kinase 5- MAP Kinase Kinase 5
- MAPKK-5 Protein Kinase
- MAPKK 5 Protein Kinase
- MAPKK5 Protein Kinase
- MAP2K5 Protein
- MAPK-ERK Kinase 5
- MAPK ERK Kinase 5
- Mitogen-Activated Protein Kinase Kinase 5
- Mitogen Activated Protein Kinase Kinase 5
|
Below are MeSH descriptors whose meaning is more general than "MAP Kinase Kinase 5".
Below are MeSH descriptors whose meaning is more specific than "MAP Kinase Kinase 5".
This graph shows the total number of publications written about "MAP Kinase Kinase 5" by people in this website by year, and whether "MAP Kinase Kinase 5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2008 | 3 | 0 | 3 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "MAP Kinase Kinase 5" by people in Profiles.
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A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells. J Cell Biol. 2022 07 04; 221(7).
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The MEK5-ERK5 Kinase Axis Controls Lipid Metabolism in Small-Cell Lung Cancer. Cancer Res. 2020 03 15; 80(6):1293-1303.
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p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction. Circ Res. 2012 Feb 17; 110(4):536-50.
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FSP-1 silencing in bone marrow cells suppresses neointima formation in vein graft. Circ Res. 2012 Jan 20; 110(2):230-40.
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Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype. Breast Cancer Res. 2008; 10(6):R105.
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Effects of MEK5/ERK5 association on small ubiquitin-related modification of ERK5: implications for diabetic ventricular dysfunction after myocardial infarction. Circ Res. 2008 Jun 06; 102(11):1416-25.
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Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells. Biochem Biophys Res Commun. 2008 May 23; 370(1):159-63.
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Protein kinase-mediated regulation of calcineurin through the phosphorylation of modulatory calcineurin-interacting protein 1. J Biol Chem. 2006 Mar 24; 281(12):7717-26.
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Big mitogen-activated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis. Circ Res. 2004 Feb 20; 94(3):362-9.
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ERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons. Proc Natl Acad Sci U S A. 2003 Jul 08; 100(14):8532-7.