"Peptidomimetics" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that are designed to mimic the 3D structure of a natural peptide or protein.
| Descriptor ID |
D057786
|
| MeSH Number(s) |
D27.505.519.828
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Peptidomimetics".
Below are MeSH descriptors whose meaning is more specific than "Peptidomimetics".
This graph shows the total number of publications written about "Peptidomimetics" by people in this website by year, and whether "Peptidomimetics" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2020 | 2 | 1 | 3 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Peptidomimetics" by people in Profiles.
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Pharmacologically Targeting the Fibroblast Growth Factor 14 Interaction Site on the Voltage-Gated Na+ Channel 1.6 Enables Isoform-Selective Modulation. Int J Mol Sci. 2021 Dec 17; 22(24).
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A novel peptidomimetic therapeutic for selective suppression of lung cancer stem cells over non-stem cancer cells. Bioorg Chem. 2021 11; 116:105340.
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Design, Synthesis, and Pharmacological Evaluation of Analogues Derived from the PLEV Tetrapeptide as Protein-Protein Interaction Modulators of Voltage-Gated Sodium Channel 1.6. J Med Chem. 2020 10 22; 63(20):11522-11547.
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Bidirectional Modulation of the Voltage-Gated Sodium (Nav1.6) Channel by Rationally Designed Peptidomimetics. Molecules. 2020 Jul 24; 25(15).
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Mapping Protein-Protein Interaction Interface Peptides with Jun-Fos Assisted Phage Display and Deep Sequencing. ACS Synth Biol. 2020 07 17; 9(7):1882-1896.
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Macromolecular modeling and design in Rosetta: recent methods and frameworks. Nat Methods. 2020 07; 17(7):665-680.
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Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7. Cell Chem Biol. 2019 10 17; 26(10):1365-1379.e22.
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SMAC mimetics as potential cancer therapeutics in myeloid malignancies. Br J Haematol. 2019 04; 185(2):219-231.
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Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates. Pharmacogenomics J. 2018 05 22; 18(3):436-443.
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Long-Acting Beta Agonists Enhance Allergic Airway Disease. PLoS One. 2015; 10(11):e0142212.