NAV1.6 Voltage-Gated Sodium Channel
"NAV1.6 Voltage-Gated Sodium Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A voltage-gated sodium channel subtype found widely expressed in neurons of the central and peripheral nervous systems. Defects in the SCN8A gene which codes for the alpha subunit of this sodium channel are associated with ATAXIA and cognitive deficits.
Descriptor ID |
D062557
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MeSH Number(s) |
D12.776.157.530.400.875.750.600 D12.776.543.550.450.875.750.600 D12.776.543.585.400.875.750.600 D12.776.631.960.600
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Concept/Terms |
NAV1.6 Voltage-Gated Sodium Channel- NAV1.6 Voltage-Gated Sodium Channel
- NAV1.6 Voltage Gated Sodium Channel
- Voltage-Gated Sodium Channel Type 8
- Voltage Gated Sodium Channel Type 8
- Type 8 Voltage-Gated Sodium Channel
- Type 8 Voltage Gated Sodium Channel
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Below are MeSH descriptors whose meaning is more general than "NAV1.6 Voltage-Gated Sodium Channel".
Below are MeSH descriptors whose meaning is more specific than "NAV1.6 Voltage-Gated Sodium Channel".
This graph shows the total number of publications written about "NAV1.6 Voltage-Gated Sodium Channel" by people in this website by year, and whether "NAV1.6 Voltage-Gated Sodium Channel" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2004 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2016 | 1 | 1 | 2 |
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Below are the most recent publications written about "NAV1.6 Voltage-Gated Sodium Channel" by people in Profiles.
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Reassembly of Excitable Domains after CNS Axon Regeneration. J Neurosci. 2016 08 31; 36(35):9148-60.
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SCN8A Epileptic Encephalopathy: Detection of Fetal Seizures Guides Multidisciplinary Approach to Diagnosis and Treatment. Pediatr Neurol. 2016 11; 64:87-91.
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Skin-derived precursor Schwann cell myelination capacity in focal tibial demyelination. Muscle Nerve. 2014 Aug; 50(2):262-72.
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Genetic reduction of the a1 subunit of Na/K-ATPase corrects multiple hippocampal phenotypes in Angelman syndrome. Cell Rep. 2013 Aug 15; 4(3):405-12.
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Where is the spike generator of the cochlear nerve? Voltage-gated sodium channels in the mouse cochlea. J Neurosci. 2005 Jul 20; 25(29):6857-68.
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Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture. J Neurosci. 2004 Apr 21; 24(16):4030-42.
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Paranodal transverse bands are required for maintenance but not initiation of Nav1.6 sodium channel clustering in CNS optic nerve axons. Glia. 2003 Nov; 44(2):173-82.