Mitogen-Activated Protein Kinase 7
"Mitogen-Activated Protein Kinase 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 110-kDa extracellular signal-regulated MAP kinase that is activated in response to cellular stress and by GROWTH FACTOR RECEPTORS-mediated pathways.
| Descriptor ID |
D048054
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.567.249.937 D12.644.360.450.169.937 D12.776.476.450.169.937
|
| Concept/Terms |
Mitogen-Activated Protein Kinase 7- Mitogen-Activated Protein Kinase 7
- Mitogen Activated Protein Kinase 7
- Extracellular Signal-Regulated Kinase 5
- Extracellular Signal Regulated Kinase 5
- MAPK7 Mitogen-Activated Protein Kinase
- MAPK7 Mitogen Activated Protein Kinase
- ERK5 Kinase
- Kinase, ERK5
- Big MAP Kinase 1
- BMK1 Kinase
- Kinase, BMK1
|
Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 7".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 7".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 7" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 7" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase 7" by people in Profiles.
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An ERK5-NRF2 Axis Mediates Senescence-Associated Stemness and Atherosclerosis. Circ Res. 2023 06 23; 133(1):25-44.
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Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation. Redox Biol. 2021 11; 47:102132.
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Design of a dual ERK5 kinase activation and autophosphorylation inhibitor to block cancer stem cell activity. Bioorg Med Chem Lett. 2020 12 01; 30(23):127552.
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WNK lysine deficient protein kinase 1 regulates human endometrial stromal cell decidualization, proliferation, and migration in part through mitogen-activated protein kinase 7. Biol Reprod. 2017 Sep 01; 97(3):400-412.
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Heterotrimeric G-protein, Ga16, is a critical downstream effector of non-canonical Wnt signaling and a potent inhibitor of transformed cell growth in non small cell lung cancer. PLoS One. 2013; 8(10):e76895.
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FSP-1 silencing in bone marrow cells suppresses neointima formation in vein graft. Circ Res. 2012 Jan 20; 110(2):230-40.
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ERK5 MAP kinase regulates neurogenin1 during cortical neurogenesis. PLoS One. 2009; 4(4):e5204.
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Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype. Breast Cancer Res. 2008; 10(6):R105.
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Extracellular signal-regulated kinase (ERK) 5 is necessary and sufficient to specify cortical neuronal fate. Proc Natl Acad Sci U S A. 2006 Jun 20; 103(25):9697-702.
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Protein kinase-mediated regulation of calcineurin through the phosphorylation of modulatory calcineurin-interacting protein 1. J Biol Chem. 2006 Mar 24; 281(12):7717-26.