"Estrogen Receptor alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the ESTROGEN RECEPTORS that has marked affinity for ESTRADIOL. Its expression and function differs from, and in some ways opposes, ESTROGEN RECEPTOR BETA.
| Descriptor ID |
D047628
|
| MeSH Number(s) |
D12.776.826.750.350.174
|
| Concept/Terms |
Estrogen Receptor alpha- Estrogen Receptor alpha
- Estradiol Receptor alpha
- Receptor alpha, Estradiol
- alpha, Estradiol Receptor
- Receptor alpha, Estrogen
- ERalpha
- Estrogen Receptors alpha
|
Below are MeSH descriptors whose meaning is more general than "Estrogen Receptor alpha".
Below are MeSH descriptors whose meaning is more specific than "Estrogen Receptor alpha".
This graph shows the total number of publications written about "Estrogen Receptor alpha" by people in this website by year, and whether "Estrogen Receptor alpha" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 4 | 4 |
| 2001 | 0 | 7 | 7 |
| 2002 | 0 | 6 | 6 |
| 2003 | 0 | 6 | 6 |
| 2004 | 5 | 3 | 8 |
| 2005 | 7 | 5 | 12 |
| 2006 | 11 | 4 | 15 |
| 2007 | 5 | 2 | 7 |
| 2008 | 5 | 5 | 10 |
| 2009 | 15 | 1 | 16 |
| 2010 | 6 | 6 | 12 |
| 2011 | 6 | 8 | 14 |
| 2012 | 5 | 7 | 12 |
| 2013 | 5 | 10 | 15 |
| 2014 | 11 | 8 | 19 |
| 2015 | 7 | 5 | 12 |
| 2016 | 8 | 4 | 12 |
| 2017 | 6 | 2 | 8 |
| 2018 | 9 | 3 | 12 |
| 2019 | 5 | 2 | 7 |
| 2020 | 10 | 5 | 15 |
| 2021 | 4 | 2 | 6 |
| 2022 | 4 | 0 | 4 |
| 2023 | 1 | 2 | 3 |
| 2024 | 3 | 2 | 5 |
| 2025 | 4 | 1 | 5 |
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Below are the most recent publications written about "Estrogen Receptor alpha" by people in Profiles.
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Muscle metabolic resilience and enhanced exercise adaptation by Esr1-induced remodeling of mitochondrial cristae-nucleoid architecture in males. Cell Rep Med. 2025 May 20; 6(5):102116.
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ESR1 Y537S and D538G Mutations Drive Resistance to CDK4/6 Inhibitors in Estrogen Receptor-Positive Breast Cancer. Clin Cancer Res. 2025 May 01; 31(9):1667-1675.
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Purification and biochemical characterization of mutant ligand binding domain of human estrogen receptor a protein. J Steroid Biochem Mol Biol. 2025 Jul; 251:106763.
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Suppression of hypothalamic oestrogenic signal sustains hyperprolactinemia and metabolic adaptation in lactating mice. Nat Metab. 2025 Apr; 7(4):759-777.
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Altered thermal preference by preoptic estrogen receptor alpha neurons in postpartum females. Mol Metab. 2025 Mar; 93:102108.
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Cell-cycle machinery is critical in regulating uterine steroid hormone for embryo implantation and development. J Clin Invest. 2024 Nov 15; 134(22).
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Evidence that CRISPR-Cas9 Y537S-mutant expressing breast cancer cells activate Yes-associated protein 1 to driving the conversion of normal fibroblasts into cancer-associated fibroblasts. Cell Commun Signal. 2024 Nov 14; 22(1):545.
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Identification of an ionic mechanism for ERa-mediated rapid excitation in neurons. Sci Adv. 2024 Oct 04; 10(40):eadp0696.
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27-Hydroxycholesterol acts on estrogen receptor a expressed by POMC neurons in the arcuate nucleus to modulate feeding behavior. Sci Adv. 2024 Jul 12; 10(28):eadi4746.
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Editorial: Underlying molecular interconnections of the estrogen receptor alpha and associated factors involved in breast cancer development: the way to new therapeutic approaches, volume II. Front Endocrinol (Lausanne). 2024; 15:1427468.