Mitogen-Activated Protein Kinase 3
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"Mitogen-Activated Protein Kinase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A 44-kDa extracellular signal-regulated MAP kinase that may play a role the initiation and regulation of MEIOSIS; MITOSIS; and postmitotic functions in differentiated cells. It phosphorylates a number of TRANSCRIPTION FACTORS; and MICROTUBULE-ASSOCIATED PROTEINS.
    
			
			
				
				
					
						| Descriptor ID | D048052 | 
					
						| MeSH Number(s) | D08.811.913.696.620.682.700.567.249.750 D12.644.360.450.169.750 D12.776.476.450.169.750 | 
					
						| Concept/Terms | Mitogen-Activated Protein Kinase 3Mitogen-Activated Protein Kinase 3Mitogen Activated Protein Kinase 3Meiosis-Activated Myelin Basic Protein Kinase p44(mpk)p44 MAPKProtein-Serine-Threonine Kinase p44(mpk)MAPK3 Mitogen-Activated Protein KinaseMAPK3 Mitogen Activated Protein KinaseMicrotubule-Associated Protein-2 KinaseKinase, Microtubule-Associated Protein-2Microtubule Associated Protein 2 KinaseERK1 KinaseKinase, ERK1PSTkinase p44mpkp44mpk, PSTkinaseExtracellular Signal-Regulated Kinase 1Extracellular Signal Regulated Kinase 1
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				Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 3".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 3".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 3" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 3" was a major or minor topic of these publications. 
				
					 
                    To see the data from this visualization as text, 
click here. 
                
		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1998 | 0 | 1 | 1 | 
| 1999 | 0 | 2 | 2 | 
| 2000 | 0 | 2 | 2 | 
| 2001 | 0 | 4 | 4 | 
| 2002 | 0 | 5 | 5 | 
| 2003 | 0 | 3 | 3 | 
| 2004 | 2 | 2 | 4 | 
| 2005 | 1 | 4 | 5 | 
| 2006 | 0 | 5 | 5 | 
| 2007 | 3 | 7 | 10 | 
| 2008 | 3 | 2 | 5 | 
| 2009 | 2 | 2 | 4 | 
| 2010 | 1 | 7 | 8 | 
| 2011 | 1 | 2 | 3 | 
| 2012 | 1 | 1 | 2 | 
| 2013 | 1 | 0 | 1 | 
| 2014 | 0 | 1 | 1 | 
| 2015 | 1 | 1 | 2 | 
| 2017 | 0 | 1 | 1 | 
| 2018 | 0 | 3 | 3 | 
| 2020 | 0 | 2 | 2 | 
| 2021 | 0 | 2 | 2 | 
| 2025 | 1 | 0 | 1 | 
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				Below are the most recent publications written about "Mitogen-Activated Protein Kinase 3" by people in Profiles.
						
					
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								Assessing the predicted impact of single amino acid substitutions in MAPK proteins for CAGI6 challenges. Hum Genet. 2025 Mar; 144(2-3):265-280. 
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								Circulatory Endothelin 1-Regulating RNAs Panel: Promising Biomarkers for Non-Invasive NAFLD/NASH Diagnosis and Stratification: Clinical and Molecular Pilot Study. Genes (Basel). 2021 11 18; 12(11). 
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								Cell lineage tracing links ERa loss in Erbb2-positive breast cancers to the arising of a highly aggressive breast cancer subtype. Proc Natl Acad Sci U S A. 2021 05 25; 118(21). 
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								MYC protein stability is negatively regulated by BRD4. Proc Natl Acad Sci U S A. 2020 06 16; 117(24):13457-13467. 
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								Differential functions of ERK1 and ERK2 in lung metastasis processes in triple-negative breast cancer. Sci Rep. 2020 05 22; 10(1):8537. 
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								Tie-2 Cre-Mediated Deficiency of Extracellular Signal-Regulated Kinase 2 Potentiates Experimental Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension in Neonatal Mice. Int J Mol Sci. 2020 Mar 31; 21(7). 
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								TGF-? Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma. Cell Rep. 2018 06 26; 23(13):3798-3812.e8. 
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								Hyperoxia Disrupts Extracellular Signal-Regulated Kinases 1/2-Induced Angiogenesis in the Developing Lungs. Int J Mol Sci. 2018 May 20; 19(5). 
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								Effect of ulixertinib, a novel ERK1/2 inhibitor, on the QT/QTc interval in patients with advanced solid tumor malignancies. Cancer Chemother Pharmacol. 2018 06; 81(6):1129-1141. 
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								Endocrine, Paracrine, and Autocrine Signaling Pathways That Regulate Ovulation. Trends Endocrinol Metab. 2018 05; 29(5):313-325.