Mitogen-Activated Protein Kinase 3
"Mitogen-Activated Protein Kinase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 44-kDa extracellular signal-regulated MAP kinase that may play a role the initiation and regulation of MEIOSIS; MITOSIS; and postmitotic functions in differentiated cells. It phosphorylates a number of TRANSCRIPTION FACTORS; and MICROTUBULE-ASSOCIATED PROTEINS.
| Descriptor ID |
D048052
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.567.249.750 D12.644.360.450.169.750 D12.776.476.450.169.750
|
| Concept/Terms |
Mitogen-Activated Protein Kinase 3- Mitogen-Activated Protein Kinase 3
- Mitogen Activated Protein Kinase 3
- Meiosis-Activated Myelin Basic Protein Kinase p44(mpk)
- p44 MAPK
- Protein-Serine-Threonine Kinase p44(mpk)
- MAPK3 Mitogen-Activated Protein Kinase
- MAPK3 Mitogen Activated Protein Kinase
- Microtubule-Associated Protein-2 Kinase
- Kinase, Microtubule-Associated Protein-2
- Microtubule Associated Protein 2 Kinase
- ERK1 Kinase
- Kinase, ERK1
- PSTkinase p44mpk
- p44mpk, PSTkinase
- Extracellular Signal-Regulated Kinase 1
- Extracellular Signal Regulated Kinase 1
|
Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 3".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 3".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 3" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1995 | 0 | 2 | 2 |
| 1997 | 0 | 3 | 3 |
| 1998 | 0 | 6 | 6 |
| 1999 | 0 | 6 | 6 |
| 2000 | 0 | 8 | 8 |
| 2001 | 0 | 13 | 13 |
| 2002 | 0 | 18 | 18 |
| 2003 | 0 | 11 | 11 |
| 2004 | 2 | 9 | 11 |
| 2005 | 4 | 6 | 10 |
| 2006 | 1 | 13 | 14 |
| 2007 | 5 | 12 | 17 |
| 2008 | 4 | 7 | 11 |
| 2009 | 5 | 10 | 15 |
| 2010 | 2 | 7 | 9 |
| 2011 | 2 | 2 | 4 |
| 2012 | 2 | 3 | 5 |
| 2013 | 1 | 3 | 4 |
| 2014 | 1 | 2 | 3 |
| 2015 | 1 | 4 | 5 |
| 2016 | 0 | 4 | 4 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 4 | 4 |
| 2020 | 1 | 2 | 3 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase 3" by people in Profiles.
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Cell lineage tracing links ERa loss in Erbb2-positive breast cancers to the arising of a highly aggressive breast cancer subtype. Proc Natl Acad Sci U S A. 2021 05 25; 118(21).
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MYC protein stability is negatively regulated by BRD4. Proc Natl Acad Sci U S A. 2020 06 16; 117(24):13457-13467.
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Differential functions of ERK1 and ERK2 in lung metastasis processes in triple-negative breast cancer. Sci Rep. 2020 05 22; 10(1):8537.
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Tie-2 Cre-Mediated Deficiency of Extracellular Signal-Regulated Kinase 2 Potentiates Experimental Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension in Neonatal Mice. Int J Mol Sci. 2020 Mar 31; 21(7).
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Hyperoxia Disrupts Extracellular Signal-Regulated Kinases 1/2-Induced Angiogenesis in the Developing Lungs. Int J Mol Sci. 2018 May 20; 19(5).
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Effect of ulixertinib, a novel ERK1/2 inhibitor, on the QT/QTc interval in patients with advanced solid tumor malignancies. Cancer Chemother Pharmacol. 2018 06; 81(6):1129-1141.
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Endocrine, Paracrine, and Autocrine Signaling Pathways That Regulate Ovulation. Trends Endocrinol Metab. 2018 05; 29(5):313-325.
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Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors. JCI Insight. 2018 02 22; 3(4).
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First-in-Class ERK1/2 Inhibitor Ulixertinib (BVD-523) in Patients with MAPK Mutant Advanced Solid Tumors: Results of a Phase I Dose-Escalation and Expansion Study. Cancer Discov. 2018 02; 8(2):184-195.
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Effects of ?-blockers on house dust mite-driven murine models pre- and post-development of an asthma phenotype. Pulm Pharmacol Ther. 2017 Oct; 46:30-40.