"MAP Kinase Kinase 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES. It takes part in a SIGNAL TRANSDUCTION pathway that is activated in response to CYTOKINES.
| Descriptor ID |
D048688
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| MeSH Number(s) |
D08.811.913.696.620.682.700.565.700 D08.811.913.696.620.682.725.200.700 D12.644.360.440.700 D12.776.476.440.700
|
| Concept/Terms |
MAP Kinase Kinase 7- MAP Kinase Kinase 7
- PRKMK7
- Mitogen-Activated Protein Kinase Kinase 7
- Mitogen Activated Protein Kinase Kinase 7
- MAPKK7 Protein Kinase
- Protein Kinase, MAPKK7
- MEK7 Protein Kinase
- Protein Kinase, MEK7
- SKK4 Protein Kinase
- Protein Kinase, SKK4
- JNK-Activating Kinase 2
- JNK Activating Kinase 2
- SEK2 Protein Kinase
- Protein Kinase, SEK2
|
Below are MeSH descriptors whose meaning is more general than "MAP Kinase Kinase 7".
Below are MeSH descriptors whose meaning is more specific than "MAP Kinase Kinase 7".
This graph shows the total number of publications written about "MAP Kinase Kinase 7" by people in this website by year, and whether "MAP Kinase Kinase 7" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "MAP Kinase Kinase 7" by people in Profiles.
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JNK1/2 represses Lkb1-deficiency-induced lung squamous cell carcinoma progression. Nat Commun. 2019 05 14; 10(1):2148.
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Novel tumor-suppressor function of KLF4 in pediatric T-cell acute lymphoblastic leukemia. Exp Hematol. 2017 09; 53:16-25.
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Inactivation of KLF4 promotes T-cell acute lymphoblastic leukemia and activates the MAP2K7 pathway. Leukemia. 2017 06; 31(6):1314-1324.
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TNF-alpha suppresses prolyl-4-hydroxylase alpha1 expression via the ASK1-JNK-NonO pathway. Arterioscler Thromb Vasc Biol. 2007 Aug; 27(8):1760-7.
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Negative regulation of JNK signaling by the tumor suppressor CYLD. J Biol Chem. 2004 Dec 31; 279(53):55161-7.
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PKC delta is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements. Genes Dev. 2003 Jul 01; 17(13):1663-76.
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Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells. J Biol Chem. 2003 May 23; 278(21):19245-56.
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Stimulus-specific requirements for MAP3 kinases in activating the JNK pathway. J Biol Chem. 2002 Dec 20; 277(51):49105-10.
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The dual specificity JKAP specifically activates the c-Jun N-terminal kinase pathway. J Biol Chem. 2002 Sep 27; 277(39):36592-601.
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Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation. Mol Cell Biol. 2000 Apr; 20(7):2334-42.