"Plectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytoskeletal linker protein with a molecular weight of greater than 500 kDa. It binds INTERMEDIATE FILAMENTS; MICROTUBULES; and ACTIN CYTOSKELETON and plays a central role in the organization and stability of the CYTOSKELETON. Plectin is phosphorylated by CALMODULIN KINASE; PROTEIN KINASE A; and PROTEIN KINASE C.
| Descriptor ID |
D051190
|
| MeSH Number(s) |
D12.776.220.790.750 D12.776.744.736
|
| Concept/Terms |
Plectin- Plectin
- Hemidesmosomal Protein HD1
- HD1, Hemidesmosomal Protein
- 500-kDa HD1 Protein
- 500 kDa HD1 Protein
- HD1 Protein, 500-kDa
|
Below are MeSH descriptors whose meaning is more general than "Plectin".
Below are MeSH descriptors whose meaning is more specific than "Plectin".
This graph shows the total number of publications written about "Plectin" by people in this website by year, and whether "Plectin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Plectin" by people in Profiles.
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Epidermolysis Bullosa with Pyloric Atresia and Significant Urologic Involvement. Pediatr Dermatol. 2017 Jan; 34(1):e61-e64.
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Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19414-9.
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Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma. PLoS Med. 2008 Apr 15; 5(4):e85.
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Human plectin: organization of the gene, sequence analysis, and chromosome localization (8q24). Proc Natl Acad Sci U S A. 1996 Apr 30; 93(9):4278-83.