Interferon Regulatory Factor-7
"Interferon Regulatory Factor-7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interferon regulatory factor that is induced by INTERFERONS as well as LMP-1 protein from EPSTEIN-BARR VIRUS. IRF-7 undergoes PHOSPHORYLATION prior to nuclear translocation and it activates GENETIC TRANSCRIPTION of multiple interferon GENES.
Descriptor ID |
D050839
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MeSH Number(s) |
D12.644.360.024.302.437 D12.776.157.057.050.437 D12.776.260.504.437 D12.776.476.024.385.437 D12.776.744.631 D12.776.930.332.437
|
Concept/Terms |
IRF-7C Transcription Factor- IRF-7C Transcription Factor
- Factor, IRF-7C Transcription
- IRF 7C Transcription Factor
- Transcription Factor, IRF-7C
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Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factor-7".
Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factor-7".
This graph shows the total number of publications written about "Interferon Regulatory Factor-7" by people in this website by year, and whether "Interferon Regulatory Factor-7" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2004 | 0 | 2 | 2 |
2005 | 0 | 1 | 1 |
2008 | 2 | 0 | 2 |
2009 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2011 | 1 | 2 | 3 |
2012 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
2018 | 2 | 0 | 2 |
2019 | 1 | 0 | 1 |
2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Interferon Regulatory Factor-7" by people in Profiles.
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Transcriptomic studies revealed pathophysiological impact of COVID-19 to predominant health conditions. Brief Bioinform. 2021 11 05; 22(6).
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Inflammatory Regulation by TNF-a-Activated Adipose-Derived Stem Cells in the Human Bladder Cancer Microenvironment. Int J Mol Sci. 2021 Apr 13; 22(8).
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Interferon regulatory factor 7 (IRF7) represents a link between inflammation and fibrosis in the pathogenesis of systemic sclerosis. Ann Rheum Dis. 2019 11; 78(11):1583-1591.
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The Effect of Lipopolysaccharide on Noxa Expression Is Mediated through IRF1, 3, and 7. J Microbiol Biotechnol. 2018 Mar 28; 28(3):491-497.
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Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nat Med. 2018 03; 24(3):282-291.
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PU.1 acts as tumor suppressor for myeloma cells through direct transcriptional repression of IRF4. Oncogene. 2017 08; 36(31):4481-4497.
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Grancalcin (GCA) modulates Toll-like receptor 9 (TLR9) mediated signaling through its direct interaction with TLR9. Eur J Immunol. 2016 Mar; 46(3):712-24.
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Phospholipid scramblase 1 regulates Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells. Cell Res. 2012 Jul; 22(7):1129-39.
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Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis. Ann Rheum Dis. 2012 Jan; 71(1):114-9.
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Suppression of IRF4 by IRF1, 3, and 7 in Noxa expression is a necessary event for IFN-?-mediated tumor elimination. Mol Cancer Res. 2011 Oct; 9(10):1356-65.