Primary Graft Dysfunction
"Primary Graft Dysfunction" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of ischemia-reperfusion injury occurring in the early period following transplantation. Significant pathophysiological changes in MITOCHONDRIA are the main cause of the dysfunction. It is most often seen in the transplanted lung, liver, or kidney and can lead to GRAFT REJECTION.
| Descriptor ID |
D055031
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| MeSH Number(s) |
C14.907.725.675 C23.550.767.877.750
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Primary Graft Dysfunction".
Below are MeSH descriptors whose meaning is more specific than "Primary Graft Dysfunction".
This graph shows the total number of publications written about "Primary Graft Dysfunction" by people in this website by year, and whether "Primary Graft Dysfunction" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2015 | 2 | 1 | 3 |
| 2017 | 3 | 0 | 3 |
| 2018 | 2 | 1 | 3 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 2 | 0 | 2 |
| 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Primary Graft Dysfunction" by people in Profiles.
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Primary Graft Dysfunction in Lung Transplantation: A Review of Mechanisms and Future Applications. Transplantation. 2023 08 01; 107(8):1687-1697.
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Intraoperative Red Blood Cell Transfusion and Primary Graft Dysfunction After Lung Transplantation. Transplantation. 2023 07 01; 107(7):1573-1579.
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Plasma protein biomarkers for primary graft dysfunction after lung transplantation: a single-center cohort analysis. Sci Rep. 2022 09 27; 12(1):16137.
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Effect of mode of intraoperative support on primary graft dysfunction after lung transplant. J Thorac Cardiovasc Surg. 2022 11; 164(5):1351-1361.e4.
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Analysis of sex-based differences in clinical and molecular responses to ischemia reperfusion after lung transplantation. Respir Res. 2021 Dec 22; 22(1):318.
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Residual endotoxin induces primary graft dysfunction through ischemia/reperfusion-primed alveolar macrophages. J Clin Invest. 2020 08 03; 130(8):4456-4469.
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Evaluation of the INSPIRE trial and its implications for lung transplantation with normothermic portable ex?vivo lung perfusion. J Thorac Cardiovasc Surg. 2019 10; 158(4):1259-1263.
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Impairment of the Akt pathway in transplanted Type 1 diabetic hearts is associated with post-transplant graft injury. Interact Cardiovasc Thorac Surg. 2018 12 01; 27(6):884-894.
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Association of methacholine challenge test with diagnosis of chronic lung allograft dysfunction in lung transplant patients. Clin Transplant. 2018 10; 32(10):e13397.
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EVLP: Ready for Prime Time? Semin Thorac Cardiovasc Surg. 2019; 31(1):1-6.