Chaperonin Containing TCP-1
"Chaperonin Containing TCP-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group II chaperonin found in eukaryotic CYTOSOL. It is comprised of eight subunits with each subunit encoded by a separate gene. This chaperonin is named after one of its subunits which is a T-COMPLEX REGION-encoded polypeptide.
| Descriptor ID |
D056404
|
| MeSH Number(s) |
D08.811.277.040.025.142.750.500 D12.776.580.216.210.795.500
|
| Concept/Terms |
Chaperonin Containing TCP-1- Chaperonin Containing TCP-1
- Chaperonin Containing TCP 1
- Cytosolic Molecular Chaperone CCT
- Cytosolic Chaperonin
- Chaperonin, Cytosolic
- Chaperonin CCT
- Chaperonin Containing t-Complex Polypeptide
- Chaperonin Containing t Complex Polypeptide
Chaperonin CCT, alpha Subunit- Chaperonin CCT, alpha Subunit
- Testis Complex Polypeptide 1
- t-Complex Polypeptide 1
- t Complex Polypeptide 1
- t-Complex Protein 1
- t Complex Protein 1
- Chaperonin Containing TCP1, Subunit 1
- Chaperonin-Containing T-Complex Polypeptide 1
- Chaperonin Containing T Complex Polypeptide 1
|
Below are MeSH descriptors whose meaning is more general than "Chaperonin Containing TCP-1".
Below are MeSH descriptors whose meaning is more specific than "Chaperonin Containing TCP-1".
This graph shows the total number of publications written about "Chaperonin Containing TCP-1" by people in this website by year, and whether "Chaperonin Containing TCP-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Chaperonin Containing TCP-1" by people in Profiles.
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Brain malformations and seizures by impaired chaperonin function of TRiC. Science. 2024 Nov; 386(6721):516-525.
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The CCT chaperonin and actin modulate the ER and RNA-binding protein condensation during oogenesis and maintain translational repression of maternal mRNA and oocyte quality. Mol Biol Cell. 2024 Oct 01; 35(10):ar131.
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Serum Proteomics Identifies Biomarkers Associated With the Pathogenesis of Idiopathic Pulmonary Fibrosis. Mol Cell Proteomics. 2023 04; 22(4):100524.
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The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. Cell. 2019 04 18; 177(3):751-765.e15.
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Murine cytomegalovirus M72 promotes acute virus replication in vivo and is a substrate of the TRiC/CCT complex. Virology. 2018 09; 522:92-105.
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TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington's disease. Proc Natl Acad Sci U S A. 2016 09 20; 113(38):E5655-64.
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Chaperonin TRiC/CCT Recognizes Fusion Oncoprotein AML1-ETO through Subunit-Specific Interactions. Biophys J. 2016 06 07; 110(11):2377-2385.
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Chaperonin TRiC/CCT Modulates the Folding and Activity of Leukemogenic Fusion Oncoprotein AML1-ETO. J Biol Chem. 2016 Feb 26; 291(9):4732-41.
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Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis. Int J Mol Sci. 2015 Nov 06; 16(11):26706-20.
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Improved Peak Detection and Deconvolution of Native Electrospray Mass Spectra from Large Protein Complexes. J Am Soc Mass Spectrom. 2015 Dec; 26(12):2141-51.