"Integrin beta Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Integrin beta chains combine with integrin alpha chains to form heterodimeric cell surface receptors. Integrins have traditionally been classified into functional groups based on the identity of one of three beta chains present in the heterodimer. The beta chain is necessary and sufficient for integrin-dependent signaling. Its short cytoplasmic tail contains sequences critical for inside-out signaling.
| Descriptor ID |
D039641
|
| MeSH Number(s) |
D12.776.543.750.705.408.200
|
| Concept/Terms |
Integrin beta Chains- Integrin beta Chains
- beta Chains, Integrin
- Integrin beta Subunits
- beta Integrins
- Integrins, beta
|
Below are MeSH descriptors whose meaning is more general than "Integrin beta Chains".
Below are MeSH descriptors whose meaning is more specific than "Integrin beta Chains".
This graph shows the total number of publications written about "Integrin beta Chains" by people in this website by year, and whether "Integrin beta Chains" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Integrin beta Chains" by people in Profiles.
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The ?8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development. Development. 2022 03 15; 149(6).
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T-cell trafficking plays an essential role in tumor immunity. Lab Invest. 2019 01; 99(1):85-92.
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Treatment-Na?ve HIV-Infected Patients Have Fewer Gut-Homing ?7 Memory CD4 T Cells than Healthy Controls. South Med J. 2017 11; 110(11):709-713.
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Glioblastoma stem cells exploit the av?8 integrin-TGF?1 signaling axis to drive tumor initiation and progression. Oncogene. 2017 11 23; 36(47):6568-6580.
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Integrin beta8 (ITGB8) activates VAV-RAC1 signaling via FAK in the acquisition of endometrial epithelial cell receptivity for blastocyst implantation. Sci Rep. 2017 05 15; 7(1):1885.
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Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nat Med. 2016 05; 22(5):497-505.
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Expansion of the spectrum of ITGB6-related disorders to adolescent alopecia, dentogingival abnormalities and intellectual disability. Eur J Hum Genet. 2016 08; 24(8):1223-7.
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Neuropilin 1 balances ?8 integrin-activated TGF? signaling to control sprouting angiogenesis in the brain. Development. 2015 Dec 15; 142(24):4363-73.
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Integrin Adhesions Suppress Syncytium Formation in the Drosophila Larval Epidermis. Curr Biol. 2015 Aug 31; 25(17):2215-27.
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The ZNF304-integrin axis protects against anoikis in cancer. Nat Commun. 2015 Jun 17; 6:7351.