"Integrin beta3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin beta subunit of approximately 85-kDa in size which has been found in INTEGRIN ALPHAIIB-containing and INTEGRIN ALPHAV-containing heterodimers. Integrin beta3 occurs as three alternatively spliced isoforms, designated beta3A-C.
| Descriptor ID |
D039661
|
| MeSH Number(s) |
D12.776.543.750.705.408.200.750
|
| Concept/Terms |
Integrin beta3- Integrin beta3
- beta3, Integrin
- CD61 Antigen
- Antigen, CD61
- GPIIIa
- beta(3) Integrin
- Platelet Glycoprotein IIIa
- Glycoprotein IIIa, Platelet
- Platelet GPIIIa
- Antigens, CD61
- CD61 Antigens
- Platelet Membrane Glycoprotein IIIa
- beta3 Integrin
- Integrin, beta3
|
Below are MeSH descriptors whose meaning is more general than "Integrin beta3".
Below are MeSH descriptors whose meaning is more specific than "Integrin beta3".
This graph shows the total number of publications written about "Integrin beta3" by people in this website by year, and whether "Integrin beta3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 2 | 2 | 4 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2011 | 2 | 1 | 3 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Integrin beta3" by people in Profiles.
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Molecular dynamics simulations corroborate recombinant expression studies carried out on three aIIb ?-propeller mutations reported in Indian Glanzmann thrombasthenia patients. J Cell Biochem. 2023 07; 124(7):989-1001.
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UV radiation resistance-associated gene (UVRAG) promotes cell proliferation, migration, invasion by regulating cyclin-dependent kinases (CDK) and integrin-?/Src signaling in breast cancer cells. Mol Cell Biochem. 2021 May; 476(5):2075-2084.
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Co-stimulatory effect of TLR2 and TLR4 stimulation on megakaryocytic development is mediated through PI3K/NF-?B and XBP-1 loop. Cell Signal. 2021 04; 80:109924.
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Decreased Jagged1 expression in vascular smooth muscle cells delays endothelial regeneration in arteriovenous graft. Cardiovasc Res. 2020 11 01; 116(13):2142-2155.
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Integrin ?3 Mediates the Endothelial-to-Mesenchymal Transition via the Notch Pathway. Cell Physiol Biochem. 2018; 49(3):985.
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Are micromegakaryocytes specific for refractory cytopenia of childhood (RCC)? A study of 38 pediatric patients with thrombocytopenia unrelated to RCC. Leuk Res. 2016 08; 47:84-7.
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Impaired integrin ?3 delays endothelial cell regeneration and contributes to arteriovenous graft failure in mice. Arterioscler Thromb Vasc Biol. 2015 Mar; 35(3):607-15.
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An integrin ?3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition. Nat Cell Biol. 2014 May; 16(5):457-68.
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Integrin-dependent neutrophil migration in the injured mouse cornea. Exp Eye Res. 2014 Mar; 120:61-70.
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Combating resistance to anti-IGFR antibody by targeting the integrin ?3-Src pathway. J Natl Cancer Inst. 2013 Oct 16; 105(20):1558-70.