"Integrin beta3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin beta subunit of approximately 85-kDa in size which has been found in INTEGRIN ALPHAIIB-containing and INTEGRIN ALPHAV-containing heterodimers. Integrin beta3 occurs as three alternatively spliced isoforms, designated beta3A-C.
| Descriptor ID |
D039661
|
| MeSH Number(s) |
D12.776.543.750.705.408.200.750
|
| Concept/Terms |
Integrin beta3- Integrin beta3
- beta3, Integrin
- CD61 Antigen
- Antigen, CD61
- GPIIIa
- beta(3) Integrin
- Platelet Glycoprotein IIIa
- Glycoprotein IIIa, Platelet
- Platelet GPIIIa
- Antigens, CD61
- CD61 Antigens
- Platelet Membrane Glycoprotein IIIa
- beta3 Integrin
- Integrin, beta3
|
Below are MeSH descriptors whose meaning is more general than "Integrin beta3".
Below are MeSH descriptors whose meaning is more specific than "Integrin beta3".
This graph shows the total number of publications written about "Integrin beta3" by people in this website by year, and whether "Integrin beta3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 |
| 2002 | 2 | 2 | 4 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2011 | 2 | 1 | 3 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Integrin beta3" by people in Profiles.
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Molecular dynamics simulations corroborate recombinant expression studies carried out on three aIIb ?-propeller mutations reported in Indian Glanzmann thrombasthenia patients. J Cell Biochem. 2023 07; 124(7):989-1001.
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Decreased Jagged1 expression in vascular smooth muscle cells delays endothelial regeneration in arteriovenous graft. Cardiovasc Res. 2020 11 01; 116(13):2142-2155.
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Integrin ?3 Mediates the Endothelial-to-Mesenchymal Transition via the Notch Pathway. Cell Physiol Biochem. 2018; 49(3):985.
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Are micromegakaryocytes specific for refractory cytopenia of childhood (RCC)? A study of 38 pediatric patients with thrombocytopenia unrelated to RCC. Leuk Res. 2016 08; 47:84-7.
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Impaired integrin ?3 delays endothelial cell regeneration and contributes to arteriovenous graft failure in mice. Arterioscler Thromb Vasc Biol. 2015 Mar; 35(3):607-15.
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An integrin ?3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition. Nat Cell Biol. 2014 May; 16(5):457-68.
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Distinct roles for the a , ? and ?1 isoforms of protein phosphatase 1 in the outside-in aIIb?3 integrin signalling-dependent functions. Thromb Haemost. 2013 Jan; 109(1):118-26.
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Role of integrin-?3 protein in macrophage polarization and regeneration of injured muscle. J Biol Chem. 2012 Feb 24; 287(9):6177-86.
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Regulation of endothelial cell activation and angiogenesis by injectable peptide nanofibers. Acta Biomater. 2012 Jan; 8(1):154-64.
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Association of the platelet GPIIb/IIIa polymorphism with atherosclerotic plaque morphology: the Atherosclerosis Risk in Communities (ARIC) Study. Atherosclerosis. 2011 May; 216(1):151-6.