"Chaperonins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of multisubunit protein complexes that form into large cylindrical structures which bind to and encapsulate non-native proteins. Chaperonins utilize the energy of ATP hydrolysis to enhance the efficiency of PROTEIN FOLDING reactions and thereby help proteins reach their functional conformation. The family of chaperonins is split into GROUP I CHAPERONINS, and GROUP II CHAPERONINS, with each group having its own repertoire of protein subunits and subcellular preferences.
| Descriptor ID |
D018833
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| MeSH Number(s) |
D08.811.277.040.025.142 D12.776.580.216.210
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chaperonins".
Below are MeSH descriptors whose meaning is more specific than "Chaperonins".
This graph shows the total number of publications written about "Chaperonins" by people in this website by year, and whether "Chaperonins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chaperonins" by people in Profiles.
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Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle. EMBO J. 2012 Feb 01; 31(3):720-30.
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Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT. Nat Struct Mol Biol. 2008 Jul; 15(7):746-53.
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Validation of the MycoAlign system for Mycobacterium spp. identification. Diagn Microbiol Infect Dis. 2007 Sep; 59(1):105-8.
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Clinical and molecular analysis of macrolide resistance in Mycobacterium avium complex lung disease. Am J Respir Crit Care Med. 2006 Oct 15; 174(8):928-34.
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Pulsed-field gel electrophoresis study of Mycobacterium abscessus isolates previously affected by DNA degradation. J Clin Microbiol. 2004 Dec; 42(12):5582-7.
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Construction, expression and identification of a recombinant BCG vaccine encoding human Mycobacterium tuberculosis heat shock protein 65. J Huazhong Univ Sci Technolog Med Sci. 2004; 24(2):107-11, 123.
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Perspectives on the origin of microfilaments, microtubules, the relevant chaperonin system and cytoskeletal motors--a commentary on the spirochaete origin of flagella. Cell Res. 2003 Aug; 13(4):219-27.
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The beta 2-adrenergic agonist salbutamol potentiates oral induction of tolerance, suppressing adjuvant arthritis and antigen-specific immunity. J Immunol. 2002 Nov 01; 169(9):5028-35.
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Dynamics of mycobacterial HSP65-induced T-cell cytokine expression during oral tolerance induction in adjuvant arthritis. Rheumatology (Oxford). 2002 Jul; 41(7):775-9.
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Genes in a refined Smith-Magenis syndrome critical deletion interval on chromosome 17p11.2 and the syntenic region of the mouse. Genome Res. 2002 May; 12(5):713-28.