"DNA Helicases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening. In addition DNA helicases are DNA-dependent ATPases that harness the free energy of ATP hydrolysis to translocate DNA strands.
| Descriptor ID |
D004265
|
| MeSH Number(s) |
D08.811.277.040.025.159 D08.811.399.340
|
| Concept/Terms |
DNA Helicases- DNA Helicases
- Helicases, DNA
- DNA Unwinding Proteins
- Unwinding Proteins, DNA
ATP-Dependent DNA Helicases- ATP-Dependent DNA Helicases
- ATP Dependent DNA Helicases
- DNA Helicases, ATP-Dependent
- Helicases, ATP-Dependent DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA Helicases".
Below are MeSH descriptors whose meaning is more specific than "DNA Helicases".
This graph shows the total number of publications written about "DNA Helicases" by people in this website by year, and whether "DNA Helicases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1996 | 1 | 0 | 1 |
| 1997 | 3 | 0 | 3 |
| 1998 | 1 | 0 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 8 | 0 | 8 |
| 2003 | 6 | 1 | 7 |
| 2004 | 0 | 1 | 1 |
| 2005 | 3 | 5 | 8 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 3 | 4 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 3 | 3 | 6 |
| 2011 | 4 | 1 | 5 |
| 2012 | 2 | 3 | 5 |
| 2013 | 3 | 4 | 7 |
| 2014 | 0 | 4 | 4 |
| 2015 | 1 | 3 | 4 |
| 2016 | 5 | 3 | 8 |
| 2017 | 5 | 5 | 10 |
| 2018 | 1 | 2 | 3 |
| 2019 | 2 | 3 | 5 |
| 2020 | 0 | 3 | 3 |
| 2021 | 0 | 2 | 2 |
| 2022 | 4 | 6 | 10 |
| 2023 | 0 | 8 | 8 |
| 2024 | 2 | 3 | 5 |
| 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "DNA Helicases" by people in Profiles.
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Conformational switching of Arp5 subunit regulates INO80 chromatin remodeling. Nucleic Acids Res. 2025 Jan 11; 53(2).
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Frontal lobe intra-axial schwannoma harboring a CHD7::VGLL3 fusion and heterozygous TSC2 p.F1510del mutation in a young child. Mol Biol Rep. 2025 Jan 10; 52(1):112.
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ATRX silences Cartpt expression in osteoblastic cells during skeletal development. J Clin Invest. 2025 Jan 02; 135(1).
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Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences. Nat Genet. 2024 Sep; 56(9):1832-1840.
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BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or menin inhibitor. Blood. 2024 05 16; 143(20):2059-2072.
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Enhancer switching in cell lineage priming is linked to eRNA, Brg1's AT-hook, and SWI/SNF recruitment. Mol Cell. 2024 May 16; 84(10):1855-1869.e5.
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SMARCA4 is a haploinsufficient B cell lymphoma tumor suppressor that fine-tunes centrocyte cell fate decisions. Cancer Cell. 2024 Apr 08; 42(4):605-622.e11.
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High Clinical Exome Sequencing Diagnostic Rates and Novel Phenotypic Expansions for Nonisolated Microphthalmia, Anophthalmia, and Coloboma. Invest Ophthalmol Vis Sci. 2024 Mar 05; 65(3):25.
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Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nat Commun. 2024 Feb 08; 15(1):1203.
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Life, the genome and everything. J Bacteriol. 2023 12 19; 205(12):e0027223.