"DNA Helicases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening. In addition DNA helicases are DNA-dependent ATPases that harness the free energy of ATP hydrolysis to translocate DNA strands.
| Descriptor ID |
D004265
|
| MeSH Number(s) |
D08.811.277.040.025.159 D08.811.399.340
|
| Concept/Terms |
DNA Helicases- DNA Helicases
- Helicases, DNA
- DNA Unwinding Proteins
- Unwinding Proteins, DNA
ATP-Dependent DNA Helicases- ATP-Dependent DNA Helicases
- ATP Dependent DNA Helicases
- DNA Helicases, ATP-Dependent
- Helicases, ATP-Dependent DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA Helicases".
Below are MeSH descriptors whose meaning is more specific than "DNA Helicases".
This graph shows the total number of publications written about "DNA Helicases" by people in this website by year, and whether "DNA Helicases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 3 | 0 | 3 |
| 1998 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 6 | 0 | 6 |
| 2003 | 6 | 1 | 7 |
| 2004 | 0 | 1 | 1 |
| 2005 | 3 | 5 | 8 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 3 | 4 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 4 | 3 | 7 |
| 2011 | 5 | 0 | 5 |
| 2012 | 2 | 3 | 5 |
| 2013 | 3 | 4 | 7 |
| 2014 | 0 | 4 | 4 |
| 2015 | 1 | 4 | 5 |
| 2016 | 6 | 3 | 9 |
| 2017 | 7 | 6 | 13 |
| 2018 | 3 | 2 | 5 |
| 2019 | 2 | 3 | 5 |
| 2020 | 0 | 3 | 3 |
| 2021 | 0 | 2 | 2 |
| 2022 | 5 | 6 | 11 |
| 2023 | 0 | 9 | 9 |
| 2024 | 2 | 3 | 5 |
| 2025 | 4 | 1 | 5 |
| 2026 | 4 | 3 | 7 |
To return to the timeline,
click here.
Below are the most recent publications written about "DNA Helicases" by people in Profiles.
-
PARP1 hyperactivity stalls translation and triggers stress granule formation following DNA damage. J Cell Biol. 2026 Aug 03; 225(8).
-
CST complex promotes second-strand synthesis in break-induced replication. Nat Struct Mol Biol. 2026 Jul; 33(7):1075-1085.
-
Divergent roles of SPOP and CHD1 in ACSL4 regulation reveal context-dependent vulnerabilities for targeting ferroptosis. Nat Commun. 2026 Jun 30; 17(1).
-
CHD1L maintains genome integrity by facilitating okazaki fragment maturation. Nucleic Acids Res. 2026 Jun 22; 54(12).
-
Overcoming menin inhibitor resistance in AML cells with combinations including BET proteins and a dual BRG1/BRM inhibitor. Blood. 2026 06 04; 147(23):2809-2820.
-
SMARCAL1 is a new osteosarcoma predisposition gene. J Natl Cancer Inst. 2026 Jun 01; 118(6):1120-1125.
-
Frequent synaptophysin expression in SMARCA4-deficient undifferentiated carcinoma of the oesophagus: a diagnostic pitfall with therapeutic implications. J Clin Pathol. 2026 Mar 19; 79(4):229-237.
-
Paediatric Therapeutic Development Workshop on rhabdoid tumours. Br J Cancer. 2026 Jun; 134(11):1510-1528.
-
A novel cardiomyopathy phenotype linked to a CHD7 missense variant. Sci Rep. 2025 Jun 03; 15(1):19429.
-
CHD1 loss reprograms SREBP2-driven cholesterol synthesis to fuel androgen-responsive growth and castration resistance in SPOP-mutated prostate tumors. Nat Cancer. 2025 May; 6(5):854-873.