"DNA Topoisomerases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that regulate the topology of DNA by actions such as breaking, relaxing, passing, and rejoining strands of DNA in cells. These enzymes are important components of the DNA replication system. They are classified by their substrate specificities. DNA TOPOISOMERASE I enzymes act on a single strand of DNA. DNA TOPOISOMERASE II enzymes act on double strands of DNA.
Descriptor ID |
D026942
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MeSH Number(s) |
D08.811.399.403
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "DNA Topoisomerases".
Below are MeSH descriptors whose meaning is more specific than "DNA Topoisomerases".
This graph shows the total number of publications written about "DNA Topoisomerases" by people in this website by year, and whether "DNA Topoisomerases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2007 | 1 | 0 | 1 |
2011 | 2 | 0 | 2 |
2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Topoisomerases" by people in Profiles.
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Nanoblinker: Brownian motion powered bio-nanomachine for FRET detection of phagocytic phase of apoptosis. PLoS One. 2014; 9(9):e108734.
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Fluorescent probes detecting the phagocytic phase of apoptosis: enzyme-substrate complexes of topoisomerase and DNA. Molecules. 2011 Jun 03; 16(6):4599-614.
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5'OH DNA breaks in apoptosis and their labeling by topoisomerase-based approach. Methods Mol Biol. 2011; 682:77-87.
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Contributions of the combined effects of topoisomerase mutations toward fluoroquinolone resistance in Escherichia coli. Antimicrob Agents Chemother. 2007 Nov; 51(11):4205-8.