"RecQ Helicases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging.
| Descriptor ID |
D053484
|
| MeSH Number(s) |
D08.811.277.040.025.159.249 D08.811.399.340.249
|
| Concept/Terms |
RecQ Helicases- RecQ Helicases
- Helicases, RecQ
- RecQ Protein
- RecQ Family of DNA Helicases
RecQL Helicase- RecQL Helicase
- Helicase, RecQL
- RECQL1 Helicase
- Helicase, RECQL1
- DNA Helicase RecQL
- DNA-Dependent ATPase Q1
- DNA Dependent ATPase Q1
- ATP-Dependent DNA Helicase Q1
- ATP Dependent DNA Helicase Q1
- DNA Helicase Q1
RecQ4 Helicase- RecQ4 Helicase
- RTS Helicase
- Helicase, RTS
- RecQL4 Helicase
- Helicase, RecQL4
- ATP-Dependent DNA Helicase Q4
- ATP Dependent DNA Helicase Q4
- DNA Helicase RecQL4
RecQ5 Helicase- RecQ5 Helicase
- Helicase, RecQ5
- RecQ5L Helicase
- Helicase, RecQ5L
- ATP-Dependent DNA Helicase Q5
- ATP Dependent DNA Helicase Q5
RecQ2 Helicase- RecQ2 Helicase
- Helicase, RecQ2
- RecQL3 Helicase
- Helicase, RecQL3
- DNA Helicase, RecQ-like type 2
- DNA Helicase, RecQ like type 2
RecQ3 Helicase- RecQ3 Helicase
- Helicase, RecQ3
- RecQL2 Helicase
- Helicase, RecQL2
|
Below are MeSH descriptors whose meaning is more general than "RecQ Helicases".
Below are MeSH descriptors whose meaning is more specific than "RecQ Helicases".
This graph shows the total number of publications written about "RecQ Helicases" by people in this website by year, and whether "RecQ Helicases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 3 | 3 |
| 2005 | 0 | 6 | 6 |
| 2006 | 1 | 5 | 6 |
| 2007 | 2 | 1 | 3 |
| 2008 | 3 | 1 | 4 |
| 2009 | 0 | 1 | 1 |
| 2010 | 6 | 1 | 7 |
| 2011 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 3 | 0 | 3 |
| 2014 | 1 | 1 | 2 |
| 2015 | 3 | 0 | 3 |
| 2016 | 3 | 0 | 3 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 2 | 4 |
| 2022 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "RecQ Helicases" by people in Profiles.
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Cancer risk among RECQL4 heterozygotes. Cancer Genet. 2022 04; 262-263:107-110.
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Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome. PLoS Genet. 2021 12; 17(12):e1009971.
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EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart. Mol Cell. 2021 07 15; 81(14):2989-3006.e9.
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Bloom syndrome in a Mexican American family with rhabdomyosarcoma: evidence of a Mexican founder mutation. Cold Spring Harb Mol Case Stud. 2021 04; 7(2).
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CARM1 regulates replication fork speed and stress response by stimulating PARP1. Mol Cell. 2021 02 18; 81(4):784-800.e8.
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RECQ DNA Helicases and Osteosarcoma. Adv Exp Med Biol. 2020; 1258:37-54.
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Enrichment of heterozygous germline RECQL4 loss-of-function variants in pediatric osteosarcoma. Cold Spring Harb Mol Case Stud. 2019 10; 5(5).
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Rad52 Restrains Resection at DNA Double-Strand Break Ends in Yeast. Mol Cell. 2019 12 05; 76(5):699-711.e6.
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Tools To Live By: Bacterial DNA Structures Illuminate Cancer. Trends Genet. 2019 05; 35(5):383-395.
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Generation of an induced pluripotent stem cell line from an individual with a heterozygous RECQL4 mutation. Stem Cell Res. 2018 12; 33:36-40.