"DNA Repair" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.
Descriptor ID |
D004260
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MeSH Number(s) |
G02.111.222 G05.219
|
Concept/Terms |
Base Excision Repair- Base Excision Repair
- Base Excision Repairs
- Excision Repair, Base
- Repair, Base Excision
- Repairs, Base Excision
|
Below are MeSH descriptors whose meaning is more general than "DNA Repair".
Below are MeSH descriptors whose meaning is more specific than "DNA Repair".
This graph shows the total number of publications written about "DNA Repair" by people in this website by year, and whether "DNA Repair" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 18 | 6 | 24 |
1995 | 19 | 7 | 26 |
1996 | 12 | 6 | 18 |
1997 | 24 | 8 | 32 |
1998 | 14 | 10 | 24 |
1999 | 24 | 12 | 36 |
2000 | 27 | 15 | 42 |
2001 | 17 | 10 | 27 |
2002 | 18 | 16 | 34 |
2003 | 23 | 14 | 37 |
2004 | 21 | 32 | 53 |
2005 | 25 | 26 | 51 |
2006 | 26 | 16 | 42 |
2007 | 32 | 26 | 58 |
2008 | 22 | 24 | 46 |
2009 | 23 | 26 | 49 |
2010 | 41 | 22 | 63 |
2011 | 18 | 28 | 46 |
2012 | 27 | 28 | 55 |
2013 | 17 | 18 | 35 |
2014 | 20 | 20 | 40 |
2015 | 26 | 24 | 50 |
2016 | 6 | 22 | 28 |
2017 | 17 | 22 | 39 |
2018 | 11 | 18 | 29 |
2019 | 13 | 19 | 32 |
2020 | 11 | 15 | 26 |
2021 | 17 | 18 | 35 |
2022 | 7 | 14 | 21 |
2023 | 4 | 14 | 18 |
2024 | 6 | 10 | 16 |
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Below are the most recent publications written about "DNA Repair" by people in Profiles.
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Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair. Nat Commun. 2024 Oct 01; 15(1):8511.
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Gene discovery from microbial gene libraries I: protection against reactive oxygen species-driven DNA damage. Microbiol Spectr. 2024 Nov 05; 12(11):e0036524.
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The DNA repair pathway as a therapeutic target to synergize with trastuzumab deruxtecan in HER2-targeted antibody-drug conjugate-resistant HER2-overexpressing breast cancer. J Exp Clin Cancer Res. 2024 Aug 21; 43(1):236.
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Strategies for the prevention or reversal of PARP inhibitor resistance. Expert Rev Anticancer Ther. 2024 Oct; 24(10):959-975.
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DNA damage response in brain tumors: A Society for Neuro-Oncology consensus review on mechanisms and translational efforts in neuro-oncology. Neuro Oncol. 2024 Aug 05; 26(8):1367-1387.
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A comprehensive study evaluating germline FANCG variants in predisposition to breast and ovarian cancer. Cancer Med. 2024 Aug; 13(16):e70103.
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Insights into the radiation and oxidative stress mechanisms in genus Deinococcus. Comput Biol Chem. 2024 Oct; 112:108161.
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Olaparib for childhood tumors harboring defects in DNA damage repair genes: arm H of the NCI-COG Pediatric MATCH trial. Oncologist. 2024 Jul 05; 29(7):638-e952.
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Ubiquitin-induced RNF168 condensation promotes DNA double-strand break repair. Proc Natl Acad Sci U S A. 2024 Jul 09; 121(28):e2322972121.
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Loss of the DNA Repair Gene RNase H2 Identifies a Unique Subset of DDR-Deficient Leiomyosarcomas. Mol Cancer Ther. 2024 Jul 02; 23(7):1057-1065.