"DNA Mismatch Repair" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA repair pathway involved in correction of errors introduced during DNA replication when an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. Excinucleases recognize the BASE PAIR MISMATCH and cause a segment of polynucleotide chain to be excised from the daughter strand, thereby removing the mismatched base. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)
Descriptor ID |
D053843
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MeSH Number(s) |
G02.111.222.220 G05.219.220
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Concept/Terms |
DNA Mismatch Repair- DNA Mismatch Repair
- Mismatch Repair, DNA
- Repair, DNA Mismatch
- Mismatch Repair
- Repair, Mismatch
|
Below are MeSH descriptors whose meaning is more general than "DNA Mismatch Repair".
Below are MeSH descriptors whose meaning is more specific than "DNA Mismatch Repair".
This graph shows the total number of publications written about "DNA Mismatch Repair" by people in this website by year, and whether "DNA Mismatch Repair" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2007 | 2 | 1 | 3 |
2008 | 1 | 1 | 2 |
2009 | 5 | 6 | 11 |
2010 | 2 | 5 | 7 |
2011 | 5 | 2 | 7 |
2012 | 2 | 3 | 5 |
2013 | 7 | 2 | 9 |
2014 | 1 | 2 | 3 |
2015 | 2 | 0 | 2 |
2016 | 4 | 4 | 8 |
2017 | 7 | 1 | 8 |
2018 | 1 | 8 | 9 |
2019 | 7 | 4 | 11 |
2020 | 3 | 1 | 4 |
2021 | 4 | 3 | 7 |
2022 | 4 | 12 | 16 |
2023 | 1 | 10 | 11 |
2024 | 3 | 10 | 13 |
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Below are the most recent publications written about "DNA Mismatch Repair" by people in Profiles.
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Genomic Alterations in DNA Mismatch Repair Genes Across Different Cancer Types. JCO Precis Oncol. 2024 Nov; 8:e2400419.
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Duration of immunotherapy in dMMR/MSI-H metastatic colorectal cancer patients. Eur J Cancer. 2024 Nov; 212:114336.
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Clinical Updates and Surveillance Recommendations for DNA Replication Repair Deficiency Syndromes in Children and Young Adults. Clin Cancer Res. 2024 Aug 15; 30(16):3378-3387.
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DNA mismatch repair defect and intratumor heterogeneous deficiency differently impact immune responses in diffuse large B-cell lymphoma. Oncoimmunology. 2024; 13(1):2384667.
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Nivolumab plus relatlimab in patients with previously treated microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer: the phase II CheckMate 142 study. J Immunother Cancer. 2024 May 31; 12(5).
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Immune checkpoint inhibitors for POLE or POLD1 proofreading-deficient metastatic colorectal cancer. Ann Oncol. 2024 Jul; 35(7):643-655.
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In?vitro data suggest a role for PMS2 Kozak sequence mutations in Lynch syndrome risk. HGG Adv. 2024 Jul 18; 5(3):100298.
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Pembrolizumab Plus Binimetinib With or Without Chemotherapy for MSS/pMMR Metastatic Colorectal Cancer: Outcomes From KEYNOTE-651 Cohorts A, C, and E. Clin Colorectal Cancer. 2024 Jun; 23(2):183-193.
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Pembrolizumab Plus mFOLFOX7 or FOLFIRI for Microsatellite Stable/Mismatch Repair-Proficient Metastatic Colorectal Cancer: KEYNOTE-651 Cohorts B and D. Clin Colorectal Cancer. 2024 Jun; 23(2):118-127.e6.
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Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study. Lancet Oncol. 2024 May; 25(5):668-682.