"Protein Stability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The ability of a protein to retain its structural conformation or its activity when subjected to physical or chemical manipulations.
| Descriptor ID |
D055550
|
| MeSH Number(s) |
G02.111.700
|
| Concept/Terms |
Protein Stability- Protein Stability
- Protein Stabilities
- Stabilities, Protein
- Stability, Protein
|
Below are MeSH descriptors whose meaning is more general than "Protein Stability".
Below are MeSH descriptors whose meaning is more specific than "Protein Stability".
This graph shows the total number of publications written about "Protein Stability" by people in this website by year, and whether "Protein Stability" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 4 | 4 |
| 2009 | 0 | 5 | 5 |
| 2010 | 0 | 6 | 6 |
| 2011 | 0 | 7 | 7 |
| 2012 | 0 | 3 | 3 |
| 2013 | 1 | 8 | 9 |
| 2014 | 1 | 6 | 7 |
| 2015 | 0 | 8 | 8 |
| 2016 | 0 | 4 | 4 |
| 2017 | 0 | 12 | 12 |
| 2018 | 0 | 7 | 7 |
| 2019 | 1 | 6 | 7 |
| 2020 | 0 | 6 | 6 |
| 2021 | 0 | 8 | 8 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 3 | 3 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Stability" by people in Profiles.
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TFEB degradation is regulated by an IKK/?-TrCP2 phosphorylation-ubiquitination cascade. Nat Commun. 2026 04 01; 17(1).
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Assessing the predicted impact of single amino acid substitutions in calmodulin for CAGI6 challenges. Hum Genet. 2025 Mar; 144(2-3):113-125.
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PKC-mediated phosphorylation governs the stability and function of CELF1 as a driver of EMT in breast epithelial cells. J Biol Chem. 2024 11; 300(11):107826.
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Stereospecific NANOG PEST Stabilization by Pin1. Biochemistry. 2024 05 07; 63(9):1067-1074.
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Mechanisms of MCL-1 Protein Stability Induced by MCL-1 Antagonists in B-Cell Malignancies. Clin Cancer Res. 2023 01 17; 29(2):446-457.
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Suppression of toxicity of the mutant huntingtin protein by its interacting compound, desonide. Proc Natl Acad Sci U S A. 2022 03 08; 119(10):e2114303119.
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Engineering a Hyperstable Yersinia pestis Outer Membrane Protein Ail Using Thermodynamic Design. J Am Chem Soc. 2022 02 02; 144(4):1545-1555.
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A previously unappreciated polymorphism in the beta chain of I-As expressed in autoimmunity-prone SJL mice: Combined impact on antibody, CD4 T cell recognition and MHC class II dimer structural stability. Mol Immunol. 2022 03; 143:17-26.
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A Structural Study of the Cytoplasmic Chaperone Effect of 14-3-3 Proteins on Ataxin-1. J Mol Biol. 2021 09 17; 433(19):167174.
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Comparison of potential inhibitors and targeting fat mass and obesity-associated protein causing diabesity through docking and molecular dynamics strategies. J Cell Biochem. 2021 11; 122(11):1625-1638.