"VDJ Recombinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recombinases involved in the rearrangement of immunity-related GENES such as IMMUNOGLOBULIN GENES and T-CELL RECEPTOR GENES.
| Descriptor ID |
D045567
|
| MeSH Number(s) |
D08.811.739.900 D08.811.913.696.445.950
|
| Concept/Terms |
VDJ Recombinases- VDJ Recombinases
- V-(D)-J Recombinase
- VDJ Recombinase
- Recombinase, VDJ
- V(D)J Recombinase
- V-D-J Recombinase
- Recombinase, V-D-J
- V D J Recombinase
Immunoglobulin Recombinases- Immunoglobulin Recombinases
- Recombinases, Immunoglobulin
- Immunoglobulin Recombinase
- Recombinase, Immunoglobulin
|
Below are MeSH descriptors whose meaning is more general than "VDJ Recombinases".
Below are MeSH descriptors whose meaning is more specific than "VDJ Recombinases".
This graph shows the total number of publications written about "VDJ Recombinases" by people in this website by year, and whether "VDJ Recombinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 3 | 3 |
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "VDJ Recombinases" by people in Profiles.
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Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia. J Exp Med. 2011 Jun 06; 208(6):1135-49.
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Understanding how the V(D)J recombinase catalyzes transesterification: distinctions between DNA cleavage and transposition. Nucleic Acids Res. 2008 May; 36(9):2864-73.
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Regulation of T-cell receptor beta-chain gene assembly by recombination signals: the beyond 12/23 restriction. Immunol Rev. 2004 Aug; 200:36-43.
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Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice. J Exp Med. 2003 Nov 03; 198(9):1439-50.
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Cutting edge: targeting of V beta to D beta rearrangement by RSSs can be mediated by the V(D)J recombinase in the absence of additional lymphoid-specific factors. J Immunol. 2003 Jan 01; 170(1):5-9.
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Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice. Mol Cell. 2002 Dec; 10(6):1379-90.
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Unequal access: regulating V(D)J recombination through chromatin remodeling. Cell. 2000 Nov 22; 103(5):699-702.
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The kappaB and V(D)J recombination signal sequence binding protein KRC regulates transcription of the mouse metastasis-associated gene S100A4/mts1. J Biol Chem. 2000 Jan 14; 275(2):913-20.
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Catalytic subunit of DNA-dependent protein kinase: impact on lymphocyte development and tumorigenesis. Proc Natl Acad Sci U S A. 1999 Feb 16; 96(4):1403-8.
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Immunoglobulin gene hypermutation in germinal centers is independent of the RAG-1 V(D)J recombinase. Immunol Rev. 1998 Apr; 162:133-41.