"Enzyme Stability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The extent to which an enzyme retains its structural conformation or its activity when subjected to storage, isolation, and purification or various other physical or chemical manipulations, including proteolytic enzymes and heat.
| Descriptor ID |
D004795
|
| MeSH Number(s) |
E05.916.360 G02.111.700.500
|
| Concept/Terms |
Enzyme Stability- Enzyme Stability
- Enzyme Stabilities
- Stabilities, Enzyme
- Stability, Enzyme
|
Below are MeSH descriptors whose meaning is more general than "Enzyme Stability".
Below are MeSH descriptors whose meaning is more specific than "Enzyme Stability".
This graph shows the total number of publications written about "Enzyme Stability" by people in this website by year, and whether "Enzyme Stability" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 0 | 2 | 2 |
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Below are the most recent publications written about "Enzyme Stability" by people in Profiles.
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Synergistic effects of functionally distinct substitutions in ?-lactamase variants shed light on the evolution of bacterial drug resistance. J Biol Chem. 2018 11 16; 293(46):17971-17984.
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A novel NAA10 variant with impaired acetyltransferase activity causes developmental delay, intellectual disability, and hypertrophic cardiomyopathy. Eur J Hum Genet. 2018 09; 26(9):1294-1305.
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Biochemical and structural characterization of a thermostable ?-glucosidase from Halothermothrix orenii for galacto-oligosaccharide synthesis. Appl Microbiol Biotechnol. 2015 Feb; 99(4):1731-44.
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Benzothiophene carboxylate derivatives as novel allosteric inhibitors of branched-chain a-ketoacid dehydrogenase kinase. J Biol Chem. 2014 Jul 25; 289(30):20583-93.
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JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis. J Cell Biol. 2013 Sep 02; 202(5):747-63.
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The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions. J Mol Biol. 2013 Jul 10; 425(13):2359-71.
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GSK3? mediates muscle pathology in myotonic dystrophy. J Clin Invest. 2012 Dec; 122(12):4461-72.
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Effect of membranes with various hydrophobic/hydrophilic properties on lipase immobilized activity and stability. J Biosci Bioeng. 2012 Feb; 113(2):166-72.
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CryoEM structure of Hsp104 and its mechanistic implication for protein disaggregation. Proc Natl Acad Sci U S A. 2010 May 04; 107(18):8135-40.
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Expression and purification of recombinant human alpha1-proteinase inhibitor and its single amino acid substituted variants in Escherichia coli for enhanced stability and biological activity. J Biotechnol. 2010 May 03; 147(1):64-72.