"Carbapenems" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of beta-lactam antibiotics in which the sulfur atom in the thiazolidine ring of the penicillin molecule is replaced by a carbon atom. THIENAMYCINS are a subgroup of carbapenems which have a sulfur atom as the first constituent of the side chain.
Descriptor ID |
D015780
|
MeSH Number(s) |
D02.065.589.099.124 D03.633.100.300.124
|
Concept/Terms |
Carbapenems- Carbapenems
- Antibiotics, Carbapenem
- Carbapenem Antibiotics
|
Below are MeSH descriptors whose meaning is more general than "Carbapenems".
Below are MeSH descriptors whose meaning is more specific than "Carbapenems".
This graph shows the total number of publications written about "Carbapenems" by people in this website by year, and whether "Carbapenems" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2005 | 0 | 2 | 2 |
2007 | 1 | 3 | 4 |
2011 | 2 | 1 | 3 |
2012 | 2 | 1 | 3 |
2013 | 0 | 1 | 1 |
2014 | 1 | 2 | 3 |
2015 | 1 | 1 | 2 |
2016 | 1 | 2 | 3 |
2017 | 1 | 1 | 2 |
2018 | 1 | 1 | 2 |
2019 | 1 | 0 | 1 |
2020 | 0 | 2 | 2 |
2021 | 2 | 2 | 4 |
2022 | 1 | 5 | 6 |
2023 | 1 | 0 | 1 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Carbapenems" by people in Profiles.
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In vitro evaluation of using ceftazidime/avibactam against carbapenem-resistant Acinetobacter baumannii. J Glob Antimicrob Resist. 2024 Sep; 38:252-255.
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Unveiling the structural features that regulate carbapenem deacylation in KPC-2 through QM/MM and interpretable machine learning. Phys Chem Chem Phys. 2023 Jan 04; 25(2):1349-1362.
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Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease. Cell. 2022 09 29; 185(20):3705-3719.e14.
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Systematic Analysis of Mobile Genetic Elements Mediating ?-Lactamase Gene Amplification in Noncarbapenemase-Producing Carbapenem-Resistant Enterobacterales Bloodstream Infections. mSystems. 2022 10 26; 7(5):e0047622.
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Evaluation of the inoculum effect of new antibiotics against carbapenem-resistant enterobacterales. Clin Microbiol Infect. 2022 Nov; 28(11):1503.e1-1503.e3.
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Evaluation of Tebipenem Hydrolysis by ?-Lactamases Prevalent in Complicated Urinary Tract Infections. Antimicrob Agents Chemother. 2022 05 17; 66(5):e0239621.
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Accessory Genomes Drive Independent Spread of Carbapenem-Resistant Klebsiella pneumoniae Clonal Groups 258 and 307 in Houston, TX. mBio. 2022 04 26; 13(2):e0049722.
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In vitro activity of imipenem/releactam and comparator agents against clinical bacterial isolates from patients with cancer. J Glob Antimicrob Resist. 2022 06; 29:1-6.
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Antibiotic Resistance Pattern Of Acinetobacter Baumannii Isolated From Bacteremia Patients In Pakistan. J Ayub Med Coll Abbottabad. 2022 Jan-Mar; 34(1):95-100.
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Local interactions with the Glu166 base and the conformation of an active site loop play key roles in carbapenem hydrolysis by the KPC-2 ?-lactamase. J Biol Chem. 2021 Jan-Jun; 296:100799.