"Lipogenesis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
De novo fat synthesis in the body. This includes the synthetic processes of FATTY ACIDS and subsequent TRIGLYCERIDES in the LIVER and the ADIPOSE TISSUE. Lipogenesis is regulated by numerous factors, including nutritional, hormonal, and genetic elements.
| Descriptor ID |
D050155
|
| MeSH Number(s) |
G02.111.528 G03.458.249
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lipogenesis".
Below are MeSH descriptors whose meaning is more specific than "Lipogenesis".
This graph shows the total number of publications written about "Lipogenesis" by people in this website by year, and whether "Lipogenesis" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 3 | 3 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 1 | 3 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 4 | 4 |
| 2017 | 2 | 1 | 3 |
| 2018 | 2 | 2 | 4 |
| 2019 | 1 | 0 | 1 |
| 2020 | 2 | 3 | 5 |
| 2021 | 0 | 4 | 4 |
| 2022 | 2 | 1 | 3 |
| 2023 | 1 | 0 | 1 |
| 2025 | 4 | 0 | 4 |
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Below are the most recent publications written about "Lipogenesis" by people in Profiles.
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Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice. J Biol Chem. 2022 10; 298(10):102401.
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Insulin action, type 2 diabetes, and branched-chain amino acids: A two-way street. Mol Metab. 2021 10; 52:101261.
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Metabolic liver disease - what's in a name? Nat Rev Endocrinol. 2021 02; 17(2):79-80.
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Leptin decreases de novo lipogenesis in patients with lipodystrophy. JCI Insight. 2020 07 23; 5(14).
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Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies. PLoS Med. 2020 06; 17(6):e1003102.
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Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Contributes to Hepatic Steatosis. Hepatology. 2019 07; 70(1):84-97.
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The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase. Cell Metab. 2018 Jun 05; 27(6):1281-1293.e7.
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Intestinal, but not hepatic, ChREBP is required for fructose tolerance. JCI Insight. 2017 12 21; 2(24).
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The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORa/?. Genes Dev. 2017 06 15; 31(12):1202-1211.
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Microbial metabolites regulate host lipid metabolism through NR5A-Hedgehog signalling. Nat Cell Biol. 2017 May; 19(5):550-557.