"Citric Acid Cycle" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A series of oxidative reactions in the breakdown of acetyl units derived from GLUCOSE; FATTY ACIDS; or AMINO ACIDS by means of tricarboxylic acid intermediates. The end products are CARBON DIOXIDE, water, and energy in the form of phosphate bonds.
| Descriptor ID |
D002952
|
| MeSH Number(s) |
G02.111.165 G03.295.342 G03.493.170
|
| Concept/Terms |
Citric Acid Cycle- Citric Acid Cycle
- Citric Acid Cycles
- Cycle, Citric Acid
- Cycles, Citric Acid
- Tricarboxylic Acid Cycle
- Cycle, Tricarboxylic Acid
- Cycles, Tricarboxylic Acid
- Tricarboxylic Acid Cycles
- Krebs Cycle
- Cycle, Krebs
|
Below are MeSH descriptors whose meaning is more general than "Citric Acid Cycle".
Below are MeSH descriptors whose meaning is more specific than "Citric Acid Cycle".
This graph shows the total number of publications written about "Citric Acid Cycle" by people in this website by year, and whether "Citric Acid Cycle" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 3 | 0 | 3 |
| 2018 | 1 | 3 | 4 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 3 | 3 |
| 2024 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Citric Acid Cycle" by people in Profiles.
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TCA metabolism regulates DNA hypermethylation in LPS and Mycobacterium tuberculosis-induced immune tolerance. Proc Natl Acad Sci U S A. 2024 10 08; 121(41):e2404841121.
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The intestine is a major contributor to circulating succinate in mice. FASEB J. 2022 10; 36(10):e22546.
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Biochemical assays of TCA cycle and ?-oxidation metabolites. Methods Cell Biol. 2020; 155:83-120.
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Serine synthesis through PHGDH coordinates nucleotide levels by maintaining central carbon metabolism. Nat Commun. 2018 12 21; 9(1):5442.
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Serine Availability Influences Mitochondrial Dynamics and Function through Lipid Metabolism. Cell Rep. 2018 03 27; 22(13):3507-3520.
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Exo-MFA - A 13C metabolic flux analysis framework to dissect tumor microenvironment-secreted exosome contributions towards cancer cell metabolism. Metab Eng. 2017 09; 43(Pt B):156-172.
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Anaplerotic Accumulation of Tricarboxylic Acid Cycle Intermediates as Well as Changes in Other Key Metabolites During Heterotopic Ossification. J Cell Biochem. 2016 Apr; 117(4):1044-53.
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Nitric oxide is a positive regulator of the Warburg effect in ovarian cancer cells. Cell Death Dis. 2014 Jun 26; 5:e1302.
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Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature. 2013 Jul 04; 499(7456):43-9.
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Real-time molecular imaging of tricarboxylic acid cycle metabolism in vivo by hyperpolarized 1-(13)C diethyl succinate. J Am Chem Soc. 2012 Jan 18; 134(2):934-43.