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JUAN MARINI

TitleAssociate Professor Emeritus
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
AddressOne Baylor Plaza
Houston, TX 77030
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    Collapse Research 
    Collapse research activities and funding
    R01GM108940     (BURRIN, DOUGLAS G)Aug 1, 2014 - Jun 30, 2024
    NIH
    Therapeutic and Metabolic Responses of Citrulline vs. Arginine Supplementation
    Role: Principal Investigator
    R03HD078447     (MARINI, JUAN)Sep 25, 2013 - Aug 31, 2015
    NIH
    Comparative Efficacy of Phenylbutyrate vs. Benzoate in Urea Cycle Disorders
    Role: Principal Investigator
    K01RR024173     (MARINI, JUAN)Jul 6, 2007 - Jun 30, 2012
    NIH
    Mouse models for studying citrulline recycling for sustaining NO production
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nguyen TC, Marini JC, Guillory B, Valladolid-Brown C, Martinez-Vargas M, Subramanyam D, Cohen D, Cirlos SC, Lam F, Stoll B, Didelija IC, Vonderohe C, Orellana R, Saini A, Pradhan S, Bashir D, Desai MS, Flores S, Virk M, Tcharmtchi H, Navaei A, Kaplan S, Lamberth L, Hulten KG, Scull BP, Allen CE, Akcan-Arikan A, Vijayan KV, Cruz MA. Pediatric Swine Model of Methicillin-Resistant Staphylococcus aureus Sepsis-Induced Coagulopathy, Disseminated Microvascular Thrombosis, and Organ Injuries. Crit Care Explor. 2023 Jun; 5(6):e0916. PMID: 37255626; PMCID: PMC10226618.
      Citations:    
    2. Gannon AL, Chacko SK, Didelija IC, Marini JC, Blesson CS. Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model. J Vis Exp. 2022 03 05; (181). PMID: 35312673.
      Citations:    Fields:    Translation:Animals
    3. Nagamani SCS, Agarwal U, Tam A, Azamian M, McMeans A, Didelija IC, Mohammad MA, Marini JC. Correction: A randomized trial to study the comparative efficacy of phenylbutyrate and benzoate on nitrogen excretion and ureagenesis in healthy volunteers. Genet Med. 2021 Nov; 23(11):2227. PMID: 33958751.
      Citations:    Fields:    
    4. Paulsen SJ, Kinstlinger IS, Marini JC, Didelija IC, Yoeli D, Grigoryan B, Miller JS, Galv?n NTN. Blood Flow Within Bioengineered 3D Printed Vascular Constructs Using the Porcine Model. Front Cardiovasc Med. 2021; 8:629313. PMID: 34164438; PMCID: PMC8215112.
      Citations:    
    5. Mohammad MA, Didelija IC, Stoll B, Nguyen TC, Marini JC. Pegylated arginine deiminase depletes plasma arginine but maintains tissue arginine availability in young pigs. Am J Physiol Endocrinol Metab. 2021 03 01; 320(3):E641-E652. PMID: 33427052; PMCID: PMC7988784.
      Citations:    Fields:    Translation:Animals
    6. Mohammad MA, Didelija IC, Marini JC. Arginase II Plays a Central Role in the Sexual Dimorphism of Arginine Metabolism in C57BL/6 Mice. J Nutr. 2020 12 10; 150(12):3133-3140. PMID: 33188387; PMCID: PMC7726119.
      Citations: 1     Fields:    Translation:Animals
    7. Mohammad MA, Didelija IC, Stoll B, Burrin DG, Marini JC. Modeling age-dependent developmental changes in the expression of genes involved in citrulline synthesis using pig enteroids. Physiol Rep. 2020 11; 8(21):e14565. PMID: 33181004; PMCID: PMC7660678.
      Citations: 1     Fields:    Translation:Animals
    8. Navaei AH, Shekerdemian LS, Mohammad MA, Coss-Bu JA, Bastero P, Ettinger NA, Orellana R, Fernandes CJ, Marini JC. Derangement of Arginine and Related Amino Acids in Children Undergoing Surgery for Congenital Heart Disease With Cardiopulmonary Bypass. Crit Care Explor. 2020 Jul; 2(7):e0150. PMID: 32766551; PMCID: PMC7368881.
      Citations: 3     
    9. Marini JC. Channeling of Citrulline for the Renal Synthesis of Guanidino Acetate. J Nutr. 2020 03 01; 150(3):423-424. PMID: 31868220.
      Citations: 1     Fields:    Translation:Animals
    10. Burrage LC, Madan S, Li X, Ali S, Mohammad M, Stroup BM, Jiang MM, Cela R, Bertin T, Jin Z, Dai J, Guffey D, Finegold M, Members of the Urea Cycle Disorders Consortium (UCDC), Nagamani S, Minard CG, Marini J, Masand P, Schady D, Shneider BL, Leung DH, Bali D, Lee B. Chronic liver disease and impaired hepatic glycogen metabolism in argininosuccinate lyase deficiency. JCI Insight. 2020 02 27; 5(4). PMID: 31990680; PMCID: PMC7101134.
      Citations: 2     Fields:    Translation:HumansAnimals
    11. Burrin D, Sangild PT, Stoll B, Thymann T, Buddington R, Marini J, Olutoye O, Shulman RJ. Translational Advances in Pediatric Nutrition and Gastroenterology: New Insights from Pig Models. Annu Rev Anim Biosci. 2020 02 15; 8:321-354. PMID: 32069436.
      Citations: 15     Fields:    Translation:HumansAnimals
    12. Mohammad MA, Didelija IC, Wang X, Stoll B, Burrin DG, Marini JC. Developmental changes in the utilization of citrulline by neonatal pigs. Am J Physiol Renal Physiol. 2020 01 01; 318(1):F175-F182. PMID: 31760772; PMCID: PMC6985816.
      Citations: 2     Fields:    Translation:Animals
    13. Blesson CS, Schutt A, Chacko S, Marini JC, Mathew PR, Tanchico D, Balakrishnan M, Yallampalli C. Sex Dependent Dysregulation of Hepatic Glucose Production in Lean Type 2 Diabetic Rats. Front Endocrinol (Lausanne). 2019; 10:538. PMID: 31447783; PMCID: PMC6691354.
      Citations: 4     Fields:    
    14. Donelson J, Wang Q, Monroe TO, Jiang X, Zhou J, Yu H, Mo Q, Sun Q, Marini JC, Wang X, Nakata PA, Hirschi KD, Wang J, Rodney GG, Wehrens XHT, Cheng N. Cardiac-specific ablation of glutaredoxin 3 leads to cardiac hypertrophy and heart failure. Physiol Rep. 2019 04; 7(8):e14071. PMID: 31033205; PMCID: PMC6487472.
      Citations: 6     Fields:    Translation:AnimalsCells
    15. Lin S, Stoll B, Robinson J, Marini JC, Hartmann B, Holst JJ, Cruz S, Lau P, Olutoye O, Fang Z, Burrin DG, Pastor JJ, Ipharraguerre IR. Differential action of TGR5 agonists on GLP-2 secretion and promotion of intestinal adaptation in a piglet short bowel model. Am J Physiol Gastrointest Liver Physiol. 2019 05 01; 316(5):G641-G652. PMID: 30920308; PMCID: PMC6580240.
      Citations:    Fields:    Translation:AnimalsCells
    16. Mohammad MA, Didelija IC, Stoll B, Marini JC. Citrulline Generation Test: What Does It Measure? JPEN J Parenter Enteral Nutr. 2019 08; 43(6):726-733. PMID: 30357864; PMCID: PMC6482105.
      Citations: 1     Fields:    Translation:Animals
    17. Wang X, Yuan Y, Didelija IC, Mohammad MA, Marini JC. Ex Vivo Enteroids Recapitulate In Vivo Citrulline Production in Mice. J Nutr. 2018 09 01; 148(9):1415-1420. PMID: 30184221; PMCID: PMC6669957.
      Citations: 2     Fields:    Translation:Animals
    18. Pankowicz FP, Barzi M, Kim KH, Legras X, Martins CS, Wooton-Kee CR, Lagor WR, Marini JC, Elsea SH, Bissig-Choisat B, Moore DD, Bissig KD. Rapid Disruption of Genes Specifically in Livers of Mice Using Multiplex CRISPR/Cas9 Editing. Gastroenterology. 2018 12; 155(6):1967-1970.e6. PMID: 30170115; PMCID: PMC6420307.
      Citations: 9     Fields:    Translation:AnimalsCells
    19. Robinson JL, Smith VA, Stoll B, Agarwal U, Premkumar MH, Lau P, Cruz SM, Manjarin R, Olutoye O, Burrin DG, Marini JC. Prematurity reduces citrulline-arginine-nitric oxide production and precedes the onset of necrotizing enterocolitis in piglets. Am J Physiol Gastrointest Liver Physiol. 2018 10 01; 315(4):G638-G649. PMID: 30048597; PMCID: PMC6415715.
      Citations: 9     Fields:    Translation:Animals
    20. Yuan Y, Mohammad MA, Betancourt A, Didelija IC, Yallampalli C, Marini JC. The Citrulline Recycling Pathway Sustains Cardiovascular Function in Arginine-Depleted Healthy Mice, but Cannot Sustain Nitric Oxide Production during Endotoxin Challenge. J Nutr. 2018 06 01; 148(6):844-850. PMID: 29878271; PMCID: PMC6670044.
      Citations: 2     Fields:    Translation:Animals
    21. Nagamani SCS, Agarwal U, Tam A, Azamian M, McMeans A, Didelija IC, Mohammad MA, Marini JC. A randomized trial to study the comparative efficacy of phenylbutyrate and benzoate on nitrogen excretion and ureagenesis in healthy volunteers. Genet Med. 2018 07; 20(7):708-716. PMID: 29693650; PMCID: PMC5924481.
      Citations: 4     Fields:    Translation:Humans
    22. Didelija IC, Mohammad MA, Marini JC. Ablation of Arginase II Spares Arginine and Abolishes the Arginine Requirement for Growth in Male Mice. J Nutr. 2017 08; 147(8):1510-1516. PMID: 28679627; PMCID: PMC5525112.
      Citations: 2     Fields:    Translation:Animals
    23. Marini JC, Agarwal U, Robinson JL, Yuan Y, Didelija IC, Stoll B, Burrin DG. The intestinal-renal axis for arginine synthesis is present and functional in the neonatal pig. Am J Physiol Endocrinol Metab. 2017 08 01; 313(2):E233-E242. PMID: 28611027; PMCID: PMC5582884.
      Citations: 13     Fields:    Translation:AnimalsCells
    24. Marini JC, Agarwal U, Didelija IC, Azamian M, Stoll B, Nagamani SC. Plasma Glutamine Is a Minor Precursor for the Synthesis of Citrulline: A Multispecies Study. J Nutr. 2017 04; 147(4):549-555. PMID: 28275102; PMCID: PMC5368584.
      Citations: 9     Fields:    Translation:HumansAnimals
    25. Agarwal U, Didelija IC, Yuan Y, Wang X, Marini JC. Supplemental Citrulline Is More Efficient Than Arginine in Increasing Systemic Arginine Availability in Mice. J Nutr. 2017 04; 147(4):596-602. PMID: 28179487; PMCID: PMC5368575.
      Citations: 20     Fields:    Translation:Animals
    26. Achreja A, Zhao H, Yang L, Yun TH, Marini J, Nagrath D. Exo-MFA - A 13C metabolic flux analysis framework to dissect tumor microenvironment-secreted exosome contributions towards cancer cell metabolism. Metab Eng. 2017 09; 43(Pt B):156-172. PMID: 28087332; PMCID: PMC7393794.
      Citations: 33     Fields:    Translation:HumansCells
    27. Pham K, Dong J, Jiang X, Qu Y, Yu H, Yang Y, Olea W, Marini JC, Chan L, Wang J, Wehrens XH, Cui X, Li Y, Hadsell DL, Cheng N. Loss of glutaredoxin 3 impedes mammary lobuloalveolar development during pregnancy and lactation. Am J Physiol Endocrinol Metab. 2017 03 01; 312(3):E136-E149. PMID: 27894063; PMCID: PMC5374299.
      Citations: 4     Fields:    Translation:AnimalsCells
    28. Yang L, Achreja A, Yeung TL, Mangala LS, Jiang D, Han C, Baddour J, Marini JC, Ni J, Nakahara R, Wahlig S, Chiba L, Kim SH, Morse J, Pradeep S, Nagaraja AS, Haemmerle M, Kyunghee N, Derichsweiler M, Plackemeier T, Mercado-Uribe I, Lopez-Berestein G, Moss T, Ram PT, Liu J, Lu X, Mok SC, Sood AK, Nagrath D. Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth. Cell Metab. 2016 11 08; 24(5):685-700. PMID: 27829138; PMCID: PMC7329194.
      Citations: 146     Fields:    Translation:HumansAnimalsCells
    29. Zhao H, Yang L, Baddour J, Achreja A, Bernard V, Moss T, Marini JC, Tudawe T, Seviour EG, San Lucas FA, Alvarez H, Gupta S, Maiti SN, Cooper L, Peehl D, Ram PT, Maitra A, Nagrath D. Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism. Elife. 2016 Feb 27; 5:e10250. PMID: 26920219; PMCID: PMC4841778.
      Citations: 356     Fields:    Translation:Cells
    30. Blesson CS, Schutt AK, Balakrishnan MP, Pautler RG, Pedersen SE, Sarkar P, Gonzales D, Zhu G, Marini JC, Chacko SK, Yallampalli U, Yallampalli C. Novel lean type 2 diabetic rat model using gestational low-protein programming. Am J Obstet Gynecol. 2016 Apr; 214(4):540.e1-540.e7. PMID: 26874300; PMCID: PMC4808600.
      Citations: 7     Fields:    Translation:Animals
    31. Marini JC. Interrelationships between glutamine and citrulline metabolism. Curr Opin Clin Nutr Metab Care. 2016 Jan; 19(1):62-6. PMID: 26560519; PMCID: PMC4712452.
      Citations: 10     Fields:    Translation:HumansAnimals
    32. Marini JC, Agarwal U, Didelija IC. Dietary arginine requirements for growth are dependent on the rate of citrulline production in mice. J Nutr. 2015 Jun; 145(6):1227-31. PMID: 25855119; PMCID: PMC4442117.
      Citations: 9     Fields:    Translation:Animals
    33. Ligthart-Melis GC, Marini JC, Engelen MP, Deutz NE. Glutamine supplementation, citrulline production, and de novo arginine synthesis: is there a relation? Am J Clin Nutr. 2015 Apr; 101(4):890-2. PMID: 25833987.
      Citations: 3     Fields:    Translation:Humans
    34. Marini JC, Didelija IC. Arginine depletion by arginine deiminase does not affect whole protein metabolism or muscle fractional protein synthesis rate in mice. PLoS One. 2015; 10(3):e0119801. PMID: 25775142; PMCID: PMC4361593.
      Citations: 8     Fields:    Translation:Animals
    35. Ng K, Stoll B, Chacko S, Saenz de Pipaon M, Lauridsen C, Gray M, Squires EJ, Marini J, Zamora IJ, Olutoye OO, Burrin DG. Vitamin E in New-Generation Lipid Emulsions Protects Against Parenteral Nutrition-Associated Liver Disease in Parenteral Nutrition-Fed Preterm Pigs. JPEN J Parenter Enteral Nutr. 2016 07; 40(5):656-71. PMID: 25596209; PMCID: PMC4504844.
      Citations: 32     Fields:    Translation:HumansAnimals
    36. . The effect of Fentanyl administration on plasma agmatine concentration in critically ill patients. J. Pediatr. Neonatal Care. 2015; (3):00118.
    37. Marini JC. Protein requirements: are we ready for new recommendations? J Nutr. 2015 Jan; 145(1):5-6. PMID: 25342701; PMCID: PMC6584165.
      Citations: 1     Fields:    Translation:Humans
    38. Marini JC, Didelija IC, Fiorotto ML. Extrarenal citrulline disposal in mice with impaired renal function. Am J Physiol Renal Physiol. 2014 Sep 15; 307(6):F660-5. PMID: 25056350; PMCID: PMC4166726.
      Citations: 12     Fields:    Translation:Animals
    39. Caneba CA, Yang L, Baddour J, Curtis R, Win J, Hartig S, Marini J, Nagrath D. Nitric oxide is a positive regulator of the Warburg effect in ovarian cancer cells. Cell Death Dis. 2014 Jun 26; 5:e1302. PMID: 24967964; PMCID: PMC4611736.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    40. Yang L, Moss T, Mangala LS, Marini J, Zhao H, Wahlig S, Armaiz-Pena G, Jiang D, Achreja A, Win J, Roopaimoole R, Rodriguez-Aguayo C, Mercado-Uribe I, Lopez-Berestein G, Liu J, Tsukamoto T, Sood AK, Ram PT, Nagrath D. Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer. Mol Syst Biol. 2014 May 05; 10:728. PMID: 24799285; PMCID: PMC4188042.
      Citations: 131     Fields:    Translation:HumansCells
    41. Radley-Crabb HG, Marini JC, Sosa HA, Castillo LI, Grounds MD, Fiorotto ML. Dystropathology increases energy expenditure and protein turnover in the mdx mouse model of duchenne muscular dystrophy. PLoS One. 2014; 9(2):e89277. PMID: 24586653; PMCID: PMC3929705.
      Citations: 26     Fields:    Translation:AnimalsCells
    42. Stoll B, Didelija IC, Burrin DG, Marini JC. De novo synthesis is the main source of ornithine for citrulline production in neonatal pigs. Am J Physiol Endocrinol Metab. 2012 Dec 01; 303(11):E1348-53. PMID: 23074237; PMCID: PMC3774079.
      Citations: 13     Fields:    Translation:AnimalsCells
    43. Nagamani SC, Shchelochkov OA, Mullins MA, Carter S, Lanpher BC, Sun Q, Kleppe S, Erez A, O'Brian Smith E, Marini JC, Members of the Urea Cycle Disorders Consortium, Lee B. A randomized controlled trial to evaluate the effects of high-dose versus low-dose of arginine therapy on hepatic function tests in argininosuccinic aciduria. Mol Genet Metab. 2012 Nov; 107(3):315-21. PMID: 23040521; PMCID: PMC3483446.
      Citations: 12     Fields:    Translation:Humans
    44. Benight NM, Stoll B, Marini JC, Burrin DG. Preventative oral methylthioadenosine is anti-inflammatory and reduces DSS-induced colitis in mice. Am J Physiol Gastrointest Liver Physiol. 2012 Jul; 303(1):G71-82. PMID: 22556140; PMCID: PMC3404577.
      Citations: 8     Fields:    Translation:Animals
    45. Nagamani SC, Campeau PM, Shchelochkov OA, Premkumar MH, Guse K, Brunetti-Pierri N, Chen Y, Sun Q, Tang Y, Palmer D, Reddy AK, Li L, Slesnick TC, Feig DI, Caudle S, Harrison D, Salviati L, Marini JC, Bryan NS, Erez A, Lee B. Nitric-oxide supplementation for treatment of long-term complications in argininosuccinic aciduria. Am J Hum Genet. 2012 May 04; 90(5):836-46. PMID: 22541557; PMCID: PMC3376491.
      Citations: 19     Fields:    Translation:HumansAnimals
    46. Haymond MW, Sun Y, Marini JC, Sauer PJ, Ma X, Sunehag AL, Chacko SK. Effect of ghrelin on glucose regulation in mice. Am J Physiol Endocrinol Metab. 2012 May 15; 302(9):E1055-62. PMID: 22338071.
      Citations: 14     Fields:    Translation:AnimalsCells
    47. Marini JC. Arginine and ornithine are the main precursors for citrulline synthesis in mice. J Nutr. 2012 Mar; 142(3):572-80. PMID: 22323761; PMCID: PMC3278269.
      Citations: 21     Fields:    Translation:Animals
    48. Erez A, Nagamani SC, Shchelochkov OA, Premkumar MH, Campeau PM, Chen Y, Garg HK, Li L, Mian A, Bertin TK, Black JO, Zeng H, Tang Y, Reddy AK, Summar M, O'Brien WE, Harrison DG, Mitch WE, Marini JC, Aschner JL, Bryan NS, Lee B. Requirement of argininosuccinate lyase for systemic nitric oxide production. Nat Med. 2011 Nov 13; 17(12):1619-26. PMID: 22081021; PMCID: PMC3348956.
      Citations: 85     Fields:    Translation:HumansAnimalsCells
    49. Benight NM, Stoll B, Chacko S, da Silva VR, Marini JC, Gregory JF, Stabler SP, Burrin DG. B-vitamin deficiency is protective against DSS-induced colitis in mice. Am J Physiol Gastrointest Liver Physiol. 2011 Aug; 301(2):G249-59. PMID: 21596995; PMCID: PMC3154603.
      Citations: 12     Fields:    Translation:Animals
    50. Marini JC. Quantitative analysis of 15N-labeled positional isomers of glutamine and citrulline via electrospray ionization tandem mass spectrometry of their dansyl derivatives. Rapid Commun Mass Spectrom. 2011 May 15; 25(9):1291-6. PMID: 21491530.
      Citations: 20     Fields:    Translation:Animals
    51. Marini JC, Lanpher BC, Scaglia F, O'Brien WE, Sun Q, Garlick PJ, Jahoor F, Lee B. Phenylbutyrate improves nitrogen disposal via an alternative pathway without eliciting an increase in protein breakdown and catabolism in control and ornithine transcarbamylase-deficient patients. Am J Clin Nutr. 2011 Jun; 93(6):1248-54. PMID: 21490144; PMCID: PMC3095500.
      Citations: 4     Fields:    Translation:Humans
    52. Brunetti-Pierri N, Lanpher B, Erez A, Ananieva EA, Islam M, Marini JC, Sun Q, Yu C, Hegde M, Li J, Wynn RM, Chuang DT, Hutson S, Lee B. Phenylbutyrate therapy for maple syrup urine disease. Hum Mol Genet. 2011 Feb 15; 20(4):631-40. PMID: 21098507; PMCID: PMC3024040.
      Citations: 33     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    53. Thame MM, Fletcher HM, Baker TM, Marini JC, Kao CC, Jahoor F. Arginine flux, but not nitric oxide synthesis, decreases in adolescent girls compared with adult women during pregnancy. J Nutr. 2011 Jan; 141(1):71-4. PMID: 21084652.
      Citations: 3     Fields:    Translation:Humans
    54. Marini JC, Keller B, Didelija IC, Castillo L, Lee B. Enteral arginase II provides ornithine for citrulline synthesis. Am J Physiol Endocrinol Metab. 2011 Jan; 300(1):E188-94. PMID: 20978229; PMCID: PMC3023202.
      Citations: 13     Fields:    Translation:Animals
    55. Marini JC, Didelija IC, Castillo L, Lee B. Plasma arginine and ornithine are the main citrulline precursors in mice infused with arginine-free diets. J Nutr. 2010 Aug; 140(8):1432-7. PMID: 20573946; PMCID: PMC2903302.
      Citations: 10     Fields:    Translation:Animals
    56. Marini JC, Didelija IC, Castillo L, Lee B. Glutamine: precursor or nitrogen donor for citrulline synthesis? Am J Physiol Endocrinol Metab. 2010 Jul; 299(1):E69-79. PMID: 20407005; PMCID: PMC2904050.
      Citations: 25     Fields:    Translation:Animals
    57. Nichols BL, Quezada-Calvillo R, Robayo-Torres CC, Ao Z, Hamaker BR, Butte NF, Marini J, Jahoor F, Sterchi EE. Mucosal maltase-glucoamylase plays a crucial role in starch digestion and prandial glucose homeostasis of mice. J Nutr. 2009 Apr; 139(4):684-90. PMID: 19193815; PMCID: PMC2666363.
      Citations: 6     Fields:    Translation:Animals
    58. Marini JC, Fox DG, Murphy MR. Nitrogen transactions along the gastrointestinal tract of cattle: A meta-analytical approach. J Anim Sci. 2008 Mar; 86(3):660-79. PMID: 18073282.
      Citations: 2     Fields:    Translation:AnimalsCells
    59. Marini JC, Erez A, Castillo L, Lee B. Interaction between murine spf-ash mutation and genetic background yields different metabolic phenotypes. Am J Physiol Endocrinol Metab. 2007 Dec; 293(6):E1764-71. PMID: 17925451.
      Citations: 10     Fields:    Translation:Animals
    60. Chowdhury SR, King DE, Willing BP, Band MR, Beever JE, Lane AB, Loor JJ, Marini JC, Rund LA, Schook LB, Van Kessel AG, Gaskins HR. Transcriptome profiling of the small intestinal epithelium in germfree versus conventional piglets. BMC Genomics. 2007 Jul 05; 8:215. PMID: 17615075; PMCID: PMC1949829.
      Citations: 50     Fields:    Translation:AnimalsCells
    61. Marini JC, Lee B, Garlick PJ. Ornithine restores ureagenesis capacity and mitigates hyperammonemia in Otc(spf-ash) mice. J Nutr. 2006 Jul; 136(7):1834-8. PMID: 16772445.
      Citations: 6     Fields:    Translation:Animals
    62. Imoberdorf R, Garlick PJ, McNurlan MA, Casella GA, Marini JC, Turgay M, Ballmer PE, B?rtsch P. Skeletal muscle protein synthesis after active or passive ascent to high altitude. Med Sci Sports Exerc. 2006 Jun; 38(6):1082-7. PMID: 16775549.
      Citations: 7     Fields:    Translation:HumansPHPublic Health
    63. Marini JC, Lee B, Garlick PJ. Reduced ornithine transcarbamylase activity does not impair ureagenesis in Otc(spf-ash) mice. J Nutr. 2006 Apr; 136(4):1017-20. PMID: 16549467.
      Citations: 4     Fields:    Translation:Animals
    64. Marini JC, Broussard SR. Hyperammonemia increases sensitivity to LPS. Mol Genet Metab. 2006 Jun; 88(2):131-7. PMID: 16497529.
      Citations: 14     Fields:    Translation:Animals
    65. Marini JC, Attene-Ramos MS. An improved analytical method for the determination of urea nitrogen isotopomers in biological samples utilizing continuous flow isotope ratio mass spectrometry. Rapid Commun Mass Spectrom. 2006; 20(24):3736-40. PMID: 17099932.
      Citations:    Fields:    Translation:Animals
    66. Marini JC, Lee B, Garlick PJ. In vivo urea kinetic studies in conscious mice. J Nutr. 2006 Jan; 136(1):202-6. PMID: 16365083.
      Citations: 5     Fields:    Translation:Animals
    67. MARINI JC, Lee B, Garlick PJ. Non-surgical alternatives to surgical procedures in mice. Lab Animals. 2006; 40:275-281.
    68. Marini JC, Van Amburgh ME. Partition of nitrogen excretion in urine and the feces of holstein replacement heifers. J Dairy Sci. 2005 May; 88(5):1778-84. PMID: 15829671.
      Citations: 8     Fields:    Translation:AnimalsPHPublic Health
    69. Scaglia F, Brunetti-Pierri N, Kleppe S, Marini J, Carter S, Garlick P, Jahoor F, O'Brien W, Lee B. Clinical consequences of urea cycle enzyme deficiencies and potential links to arginine and nitric oxide metabolism. J Nutr. 2004 10; 134(10 Suppl):2775S-2782S; discussion 2796S-2797S. PMID: 15465784.
      Citations: 21     Fields:    Translation:HumansAnimals
    70. Marini JC, Klein JD, Sands JM, Van Amburgh ME. Effect of nitrogen intake on nitrogen recycling and urea transporter abundance in lambs. J Anim Sci. 2004 Apr; 82(4):1157-64. PMID: 15080338.
      Citations: 22     Fields:    Translation:Animals
    71. Scaglia F, Marini J, Rosenberger J, Henry J, Garlick P, Lee B, Reeds P. Differential utilization of systemic and enteral ammonia for urea synthesis in control subjects and ornithine transcarbamylase deficiency carriers. Am J Clin Nutr. 2003 Oct; 78(4):749-55. PMID: 14522733.
      Citations: 1     Fields:    Translation:Humans
    72. Marini JC, Van Amburgh ME. Nitrogen metabolism and recycling in Holstein heifers. J Anim Sci. 2003 Feb; 81(2):545-52. PMID: 12643500.
      Citations: 29     Fields:    Translation:Animals
    73. MARINI JC, Simpson KW, Gerold A, Van Amburgh ME. The effect of immunization with Jackbean urease on antibody response and nitrogen recycling in mature sheep. Livest Prod Sci. 2003; (81):283-292.
    74. Ruiz R, Tedeschl LO, Marini JC, Fox DG, Pell AN, Jarvis G, Russell JB. The effect of a ruminal nitrogen (N) deficiency in dairy cows: evaluation of the cornell net carbohydrate and protein system ruminal N deficiency adjustment. J Dairy Sci. 2002 Nov; 85(11):2986-99. PMID: 12487464.
      Citations: 2     Fields:    Translation:Animals
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