"Mitochondria" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)
| Descriptor ID |
D008928
|
| MeSH Number(s) |
A11.284.430.214.190.875.564 A11.284.835.626
|
| Concept/Terms |
Mitochondrial Contraction- Mitochondrial Contraction
- Contraction, Mitochondrial
- Contractions, Mitochondrial
- Mitochondrial Contractions
|
Below are MeSH descriptors whose meaning is more general than "Mitochondria".
Below are MeSH descriptors whose meaning is more specific than "Mitochondria".
This graph shows the total number of publications written about "Mitochondria" by people in this website by year, and whether "Mitochondria" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1996 | 3 | 0 | 3 |
| 1997 | 2 | 0 | 2 |
| 1998 | 1 | 2 | 3 |
| 1999 | 4 | 5 | 9 |
| 2000 | 3 | 2 | 5 |
| 2001 | 2 | 1 | 3 |
| 2002 | 3 | 4 | 7 |
| 2003 | 5 | 4 | 9 |
| 2004 | 8 | 5 | 13 |
| 2005 | 7 | 3 | 10 |
| 2006 | 5 | 7 | 12 |
| 2007 | 1 | 12 | 13 |
| 2008 | 3 | 4 | 7 |
| 2009 | 8 | 5 | 13 |
| 2010 | 11 | 6 | 17 |
| 2011 | 11 | 7 | 18 |
| 2012 | 11 | 9 | 20 |
| 2013 | 7 | 11 | 18 |
| 2014 | 14 | 9 | 23 |
| 2015 | 20 | 6 | 26 |
| 2016 | 19 | 13 | 32 |
| 2017 | 11 | 11 | 22 |
| 2018 | 13 | 16 | 29 |
| 2019 | 11 | 10 | 21 |
| 2020 | 21 | 17 | 38 |
| 2021 | 17 | 18 | 35 |
| 2022 | 2 | 12 | 14 |
| 2023 | 10 | 15 | 25 |
| 2024 | 7 | 15 | 22 |
| 2025 | 13 | 8 | 21 |
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Below are the most recent publications written about "Mitochondria" by people in Profiles.
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Autoimmune disease risk gene ANKRD55 promotes TH17 effector function through metabolic modulation. J Exp Med. 2025 Nov 03; 222(11).
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Dissecting the effect of mitochondrial BCAT inhibition in methylmalonic acidemia. JCI Insight. 2025 Sep 09; 10(17).
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ADSL deficiency is a secondary mitochondrial disease affecting organelle homeostasis and ERK2/AKT signaling in a linear genotype-phenotype relation. Cell Rep. 2025 Sep 23; 44(9):116230.
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Dominant negative ATP5F1A variants disrupt oxidative phosphorylation causing neurological disorders. EMBO Mol Med. 2025 Oct; 17(10):2562-2585.
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Hide-and-Seek genome editing reveals that Gephyrin is required for axo-axonic synapse assembly. Proc Natl Acad Sci U S A. 2025 Aug 12; 122(32):e2500726122.
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Protection against vancomycin-associated nephrotoxicity by zileuton: role of mitochondria revealed by electron microscopic study. Ultrastruct Pathol. 2025; 49(5):414-420.
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Cell type-specific purifying selection of synonymous mitochondrial DNA variation. Proc Natl Acad Sci U S A. 2025 Jul 29; 122(30):e2505704122.
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Phase 2a/b randomised placebo-controlled dose-escalation trial of triheptanoin for ataxia-telangiectasia: treating mitochondrial dysfunction with anaplerosis. EBioMedicine. 2025 Aug; 118:105840.
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Immature Acta2R179C/+ smooth muscle cells cause moyamoya-like cerebrovascular lesions in mice prevented by boosting OXPHOS. Nat Commun. 2025 Jul 02; 16(1):6105.
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Deficits in mitochondrial dynamics and iron balance result in templated insertions. Nat Commun. 2025 Jul 01; 16(1):5454.