"Synaptosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Pinched-off nerve endings and their contents of vesicles and cytoplasm together with the attached subsynaptic area of the membrane of the post-synaptic cell. They are largely artificial structures produced by fractionation after selective centrifugation of nervous tissue homogenates.
| Descriptor ID |
D013574
|
| MeSH Number(s) |
A11.284.835.859
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Synaptosomes".
Below are MeSH descriptors whose meaning is more specific than "Synaptosomes".
This graph shows the total number of publications written about "Synaptosomes" by people in this website by year, and whether "Synaptosomes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Synaptosomes" by people in Profiles.
-
From high-throughput transcriptome characterization of individual synaptosomes to constructing the whole-brain connectome. Neuropsychopharmacology. 2024 01; 49(1):325-326.
-
Droplet-based transcriptome profiling of individual synapses. Nat Biotechnol. 2023 09; 41(9):1332-1344.
-
Molecular basis of immunogenicity to botulinum neurotoxins and uses of the defined antigenic regions. Toxicon. 2015 Dec 01; 107(Pt A):50-8.
-
The C-terminal heavy-chain domain of botulinum neurotoxin a is not the only site that binds neurons, as the N-terminal heavy-chain domain also plays a very active role in toxin-cell binding and interactions. Infect Immun. 2015 Apr; 83(4):1465-76.
-
Reduction of established antibody responses against botulinum neurotoxin A by synthetic monomethoxypolyethylene glycol peptide conjugates. J Neuroimmunol. 2014 Jul 15; 272(1-2):29-34.
-
Release, neuronal effects and removal of extracellular ?-nicotinamide adenine dinucleotide (?-NAD?) in the rat brain. Eur J Neurosci. 2012 Feb; 35(3):423-35.
-
Location of the synaptosome-binding regions on botulinum neurotoxin B. Biochemistry. 2012 Jan 10; 51(1):316-28.
-
Inhibition of botulinum neurotoxin a toxic action in vivo by synthetic synaptosome- and blocking antibody-binding regions. Protein J. 2010 Jul; 29(5):320-7.
-
Immune recognition of BoNTs A and B: how anti-toxin antibodies that bind to the heavy chain obstruct toxin action. Toxicon. 2009 Oct; 54(5):600-13.
-
Altered phosphorylation and localization of the A-type channel, Kv4.2 in status epilepticus. J Neurochem. 2008 Aug; 106(4):1929-40.