"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
| Descriptor ID |
D013569
|
| MeSH Number(s) |
A08.850 A11.284.149.165.420.780
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 2 | 4 |
| 1996 | 2 | 2 | 4 |
| 1997 | 2 | 1 | 3 |
| 1998 | 0 | 2 | 2 |
| 1999 | 3 | 6 | 9 |
| 2000 | 3 | 2 | 5 |
| 2001 | 2 | 6 | 8 |
| 2002 | 1 | 7 | 8 |
| 2003 | 8 | 3 | 11 |
| 2004 | 6 | 8 | 14 |
| 2005 | 5 | 10 | 15 |
| 2006 | 7 | 3 | 10 |
| 2007 | 7 | 4 | 11 |
| 2008 | 7 | 8 | 15 |
| 2009 | 10 | 3 | 13 |
| 2010 | 7 | 3 | 10 |
| 2011 | 11 | 2 | 13 |
| 2012 | 8 | 4 | 12 |
| 2013 | 8 | 6 | 14 |
| 2014 | 10 | 5 | 15 |
| 2015 | 7 | 7 | 14 |
| 2016 | 7 | 4 | 11 |
| 2017 | 8 | 0 | 8 |
| 2018 | 8 | 5 | 13 |
| 2019 | 3 | 5 | 8 |
| 2020 | 10 | 4 | 14 |
| 2021 | 7 | 5 | 12 |
| 2022 | 1 | 9 | 10 |
| 2023 | 1 | 7 | 8 |
| 2024 | 6 | 4 | 10 |
| 2025 | 3 | 3 | 6 |
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Below are the most recent publications written about "Synapses" by people in Profiles.
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Inferring synaptic transmission from the stochastic dynamics of the quantal content: An analytical approach. PLoS Comput Biol. 2025 May; 21(5):e1013067.
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Minding the synapse: A multi-omic approach reveals hidden regulators of neurodevelopment. Cell Syst. 2025 Apr 16; 16(4):101263.
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Inhibitory specificity from a connectomic census of mouse visual cortex. Nature. 2025 Apr; 640(8058):448-458.
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Functional connectomics reveals general wiring rule in mouse visual cortex. Nature. 2025 Apr; 640(8058):459-469.
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a2d-2 regulates synaptic GluK1 kainate receptors in Purkinje cells and motor coordination. Brain. 2025 Apr 03; 148(4):1271-1285.
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Targeting Tiam1 Enhances Hippocampal-Dependent Learning and Memory in the Adult Brain and Promotes NMDA Receptor-Mediated Synaptic Plasticity and Function. J Neurosci. 2025 Feb 05; 45(6).
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Sex-specific astrocyte regulation of spinal motor circuits by Nkx6.1. Cell Rep. 2025 01 28; 44(1):115121.
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In vivo hyperphosphorylation of tau is associated with synaptic loss and behavioral abnormalities in the absence of tau seeds. Nat Neurosci. 2025 Feb; 28(2):293-307.
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Mechanisms of memory-supporting neuronal dynamics in hippocampal area CA3. Cell. 2024 Nov 27; 187(24):6804-6819.e21.
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Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity. Hum Mol Genet. 2024 10 07; 33(20):1815-1832.