"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
| Descriptor ID |
D013569
|
| MeSH Number(s) |
A08.850 A11.284.149.165.420.780
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 2 | 4 |
| 1996 | 2 | 2 | 4 |
| 1997 | 2 | 1 | 3 |
| 1998 | 0 | 2 | 2 |
| 1999 | 3 | 6 | 9 |
| 2000 | 3 | 2 | 5 |
| 2001 | 2 | 6 | 8 |
| 2002 | 1 | 7 | 8 |
| 2003 | 8 | 3 | 11 |
| 2004 | 6 | 8 | 14 |
| 2005 | 5 | 10 | 15 |
| 2006 | 7 | 3 | 10 |
| 2007 | 7 | 4 | 11 |
| 2008 | 7 | 8 | 15 |
| 2009 | 10 | 3 | 13 |
| 2010 | 7 | 4 | 11 |
| 2011 | 11 | 2 | 13 |
| 2012 | 8 | 4 | 12 |
| 2013 | 8 | 7 | 15 |
| 2014 | 10 | 5 | 15 |
| 2015 | 9 | 7 | 16 |
| 2016 | 7 | 3 | 10 |
| 2017 | 8 | 0 | 8 |
| 2018 | 8 | 5 | 13 |
| 2019 | 3 | 5 | 8 |
| 2020 | 11 | 5 | 16 |
| 2021 | 8 | 5 | 13 |
| 2022 | 1 | 10 | 11 |
| 2023 | 2 | 7 | 9 |
| 2024 | 6 | 5 | 11 |
| 2025 | 6 | 4 | 10 |
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Below are the most recent publications written about "Synapses" by people in Profiles.
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Adaptive filters at the first olfactory synapse. PLoS Biol. 2025 Sep; 23(9):e3003405.
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Hide-and-Seek genome editing reveals that Gephyrin is required for axo-axonic synapse assembly. Proc Natl Acad Sci U S A. 2025 Aug 12; 122(32):e2500726122.
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The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex. Nat Neurosci. 2025 Aug; 28(8):1704-1715.
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Inferring synaptic transmission from the stochastic dynamics of the quantal content: An analytical approach. PLoS Comput Biol. 2025 May; 21(5):e1013067.
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Subcellular functions of tau mediate repair response and synaptic homeostasis in injury. Mol Psychiatry. 2025 Oct; 30(10):4460-4472.
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Minding the synapse: A multi-omic approach reveals hidden regulators of neurodevelopment. Cell Syst. 2025 Apr 16; 16(4):101263.
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Inhibitory specificity from a connectomic census of mouse visual cortex. Nature. 2025 Apr; 640(8058):448-458.
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Functional connectomics reveals general wiring rule in mouse visual cortex. Nature. 2025 Apr; 640(8058):459-469.
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a2d-2 regulates synaptic GluK1 kainate receptors in Purkinje cells and motor coordination. Brain. 2025 Apr 03; 148(4):1271-1285.
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Targeting Tiam1 Enhances Hippocampal-Dependent Learning and Memory in the Adult Brain and Promotes NMDA Receptor-Mediated Synaptic Plasticity and Function. J Neurosci. 2025 Feb 05; 45(6).